Barely Significant
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“may be significant”

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Need to define colonization – includes germination and establishment; also some of the “colonizers” that are first to appear on bare soil are not those with small spores but rather large spores – you might want to use During’s life cycle classifications when specifically explaining bryophyte colonization; the life span may be significant to ultimate community composition.
In a Swedish study, it was found that there may be significant socio-demographic differences between those misusing prescription analgesics, prescription sedatives, or both ( Abrahamsson & Hakansson, 2015 ), but there is still a lack of knowledge about NMUPD and different factors associated with it, especially in the Nordic countries.
Regarding the relative rate of divergence, it may be significant that the NCBI taxonomy lists only six species of Halobacterium ( https://www.ncbi.nlm.nih.gov/Taxonomy ) despite its ease of cultivation and decades of isolation studies, while more recently discovered genera with similar cultivability have far more described species ( Halorubrum , 46; Haloferax , 19; Haloarcula , 16), with new species reported frequently ( http://www.bacterio.net/halorubrum.html ).
48 At the same time, another group found that B cells and IL-10 were increased in human CC samples, which may be significant in cancer progression. 49 Most recently, B cells were proved to improve HPV-associated squamous CC, which may be activated by radiation and PD-1 blockade.
Cervical Cancer: Emerging Immune Landscape and Treatment.
Onco Targets Ther · 2020 · PMC7434518
For this reason, we carefully chose a benchmark system (a) with a good level of complexity, (b) with rich dynamic features, such as oscillations, which must not be distorted by the downscaling procedure, (c) in which the stiffness arises from pairs of reversible reactions, and (d) that is of practical interest to multidisciplinary fields. Regarding point (d), we also note that in biological systems, where the number of interacting molecules is typically low, stochastic effects may be significant for the evolution of the system. 32 , 33 Taking into consideration the above points, we have chosen a biological oscillator that mimics the cell cycle as our benchmark system.