The burden of weekly intravenous therapy may be significant in some patients with very severe CNS disease.
← all phrases
“may be significant”
In the literature
This may be significant as discontinuations due to AEs seem to occur soon after commencing treatment [ 20 ].
In addition, high prevalences (such as 59.4%) may be significant. Clinicians should be aware that this condition may be encountered more frequently and health systems should be prepared for the increased need for treatments.
Other factors affecting PFOS BAFs, including the dependency of exposure concentration on bioaccumulation ( Liu et al., 2011 ), mixture effects ( Golosovskaia et al., 2024 ), and the biotransformation and metabolism of PFAS and precursor PFAS ( Kolanczyk et al., 2023 ; Mittal & Ng 2018 ), are more difficult to evaluate in BAF studies but may be significant sources of variability.
We believe that this study may be significant for investigations on the topological physics of Weyl semimetals.
atory drugs (NSAIDs) Unanticipated causes Amniotic embolism Fat embolism Pneumothorax Acid aspiration Anaphylaxis Mechanical During recovery from anaesthesia Breath holding Bucking Bronchospasm - possible neostigmine effect Interstitial edema due to improper intravenous fluids Biting the tube, this may be significant in pediatrics The various causes may be basically divided as mechanical and pathologic causes for the purpose of understanding the pathophysiology and their prevention.
Transmission lines Limited studies indicate that rising temperatures will reduce the transmission capacity of overhead lines: this risk is expected to be low in the UK (Cradden and Harrison 2013 ), but may be significant in the USA at times of peak summer demand with reductions of up to 5.8% (Bartos et al. 2016 ).
Many previous works exclude proteins with significant homology to drugged proteins from their undrugged sets [ 3 , 14 ], even though there may be significant differences between these proteins’ properties which alter their utility as drug targets.
However, in the case of systems with 3D architecture based on AAO, which provide a high aspect ratio of pore length to pore diameter, this effect may be significant.
Such a small deletion of the normal TEL gene in t(12;21)-positive ALL may be more frequent than observed in this FISH study, and may be significant for the progression of leukemia with t(12;21).
It may be significant that transcripts of two putative CO-sensing transcriptional factors (Crp/Fnr; WP_090948317.1 and WP_064552491.1 ) were up-regulated (cluster 7; Figure S3 ) only at 44 h relative to the three other time points.
Measurement of NETs can occur through more specific assays such as MPO-DNA complex enzyme-linked immunosorbent assay, especially in the context of sepsis where there may be significant contribution from cellular debris and bacterial DNA.
These findings may be significant to the field of EAS where low-level indicators of stress are difficult to ascertain yet could be contributing to problematic behaviors in horses.
Furthermore, the variety of avoidant (or “safety”) behaviours commonly associated with social anxiety [ 70 , 71 ] mean that affected individuals may struggle or be less able to function socially, and for young people at a time in their lives when relationships with others are particularly crucial [ 72 , 73 ], the consequences may be significant and lasting.
Such changes in patient contour may be significant when utilising SGRT for patient setup, particularly if the film is applied during a course of treatment and is not reflected in the SGRT reference surface, potentially leading to the introduction of systematic positioning errors.
The high-temperature resistance mechanism of insects may be significant for use in the prevention and control of insect pests.
Our past experience suggests there may be significant cross-ethnicity differences between MA and NHW with regard to their blood-based biomarker profiles [ 14 , 26 , 40 ].
Individuals with a complicated post-transplant clinical course may experience persisting myopathies and/or neuropathies, and not all critically ill survivors recover to the same extent as there may be significant differences in recovery of muscle function and rehabilitation potential[ 58 ].
However, the coefficient on exposure to AI loses statistical significance when controlling for 1 digit occupational dummies ( Table 5 , Column 5), which could stem from attenuation bias, as measurement errors may be significant relative to the variation in actual exposure within the 1 digit occupation groups 64 .
Although in the present study the upregulation of CD2 was not associated with survival, testing this antibody may be significant for the treatment of pancreatic cancer since it provides novel insights into immunotherapy.
Bias may be significant only for cells expressing CCR3, because basophils express CD123 in a bright manner.
While this increase may be significant due to the large sample size, it may not be clinically relevant.
DNA-based NGS, fluorescence in situ hybridization, RNA and IHC assays may be significant in detecting the ALK rearrangements.
There may be significant differences in the experience of moral distress depending on the environment and patient population [ 42 ].
The anterior urethral valve (AUV) and diverticulum are not common causes of distal urethral obstruction, which may be significant but difficult to diagnose in time.