Barely Significant
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“may be significant”

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In the literature

Relative high concentration metabolites of choline metabolism may imply a poor differentiation Impressively, the high correlation coefficient of choline groups in the pair-comparison of Panc-1 vs BxPC-3 and Panc-1 vs SW1990 implied that relatively high concentration of choline-like metabolites including phosphocholine (PC) and glycerolphosphocholine (GPC) may be significant metabolic features for poor differentiation of PDAC.
The models suggested a somewhat degenerated PxxP binding groove, which may suggest lack of binding ability to this type of sequence, as well as conservation of exposed surfaces of strands β2 and β3, which may be significant for binding paramyosin, as this region has been shown to bind α-helical motifs in Pex13p SH3 and p47 phox .