Barely Significant
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“may be significant”

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In the literature

It should be cautioned, however, that these comparisons to synthetic model complexes fail to take into account the effects of electrostatic and hydrogen bonding interactions present in the protein, which may be significant. 3.7 Probing Electrostatic and Hydrogen Bonding Effects through Small Molecule TDDFT Calculations In order to quantitatively estimate the effects of hydrogen bonding on the Se XAS spectrum, we turned to TDDFT calculations of a fictitious [Fe 2 Se 2 ] n+ series in which one of the selenide bridges is hydrogen bonding with a bis-urea small molecule to simulate the interactions of the Se3A position with the neighboring protein residues ( Figure 9 and Table 4 ).
Sensitivity Analyses While previous research has shown that most police-related fatalities occur in metropolitan areas [ 3 ], there may be significant sociodemographic, economic, and other contextual differences within MSAs that are relevant to the association between police violence and preterm birth.
The majority of transplant referrals originate at dialysis clinics; thus, the dialysis facility processes and performance may be significant factors contributing to waitlisting.Whereas substantial variation in transplant rates exists at the dialysis facility level, 4 it is currently unknown how much the likelihood of waitlisting varies across dialysis facilities.