“may be significant”

The inverse relationship between myosin IIB and P-cadherin may be significant and strategic to the melanoma cell's deeper migration into the stroma in metastasis.

Regarding the rSO 2 -based indices of CVR, this study has indicated that there may be significant promise in their role as a prognostic tool.

Although it is widely accepted that there may be significant differences between temperatures experienced at the death scene and those collected retrospectively from weather stations [ 10 , 11 ], unfortunately no data loggers were placed on site and, therefore, no regression relationship was derived between ambient temperatures at site and weather station to make a retrospective correction.

Studies have shown that there may be significant underreporting and overreporting of adverse events 70 , 71 .

This information may be significant in the further development of clinical applications for GNs.

Even if early detection does not allow potentially curative resection of recurrent liver metastases, there may be significant clinical benefit to the earlier commencement of systemic chemotherapy or the use of radiofrequency ablation ( Elias et al , 2004 ; Gillams and Lees, 2005 ).

This also allowed us to investigate if a given association was sex-driven (the association may be significant for only one genetic sex, or have significantly different effect sizes between the two sex-separated GWAS).

Density of potential mosquito vectors with an extended breeding season, warm climate and abundance of microfilaremic canines may be significant factors in determining the density of human dirofilarial infections in a region ( 6 ).

However, in mine locations like that of Abbadia, particulate Hg may be significant due the presence of mine waste next to the town center, where particulate Hg can be rapidly dispersed by local winds to the surroundings.

detected no correlation between CXCR4 expression and tumor extension; therefore, this chemokine receptor may be significant for tumor invasiveness, as exhibited by hearing disability ( 53 ).

The possible impact of sex, in particular, on late effects may be significant.

Molecular coancestry Strong population structure, familial relatedness, or both, may be significant in a core collection and would negatively impact AM.

However, given the increasing number of individuals undergoing CT scans and especially the number of repeated CT scans per person, the potential public health risk may be significant.

Implications for cellular XPF–ERCC1 substrates It is unclear what role sequence preferences displayed here by XPF–ERCC1 might play in NER as filling in of the excised patch replaces lost bases, but it may be significant for other processes that XPF–ERCC1 is involved with in the cell.

96 Therefore, inadequate descending inhibition and descending facilitation may be significant causes of central sensitization and chronic pain states. 83 Downward pain inhibition is assessed psychophysically using the conditioned pain modulation (CPM) paradigm. 97 The CPM is a quantitative sensory test commonly used to assess the functionality of endogenous pain inhibition in the central ne

These findings may be significant because the qAnti-HBc level can assist in recognising at-risk patients in the early stages of CHB, as these mutations are linked with faster progression of liver injury and risk of HCC development [ 73 ].

These disparities, though small, may be significant as a single mismatch in the RNA–RNA-binding site of an sRNA-mRNA pair can abolish function of the sRNA (Hao et al., 2011 ).

The contribution of the additional transport on the values of a and rp may be significant in cells with a low water permeability, such as the squid axon (34), in which the time required to measure osmotically induced volume changes is of the order of seconds.

Thus, it can be postulated that IL-6 polymorphisms may be significant in severely affected patients, but not in low-grade obesity. 5.

It has been previously reported that AT-rich interaction domain 3A promotes the development of colorectal cancer by upregulating Aurora A ( Tang et al., 2021 ), and the expression and prognostic values of Aurora A may be significant for CRC diagnosis ( Fadaka et al., 2021 ).

Impaired formation of a GK/BAD complex proposed to associate with mitochondria and to enhance glucose oxidation may be significant for the molecular pathogenesis of the functional beta-cell defect and apoptotic beta-cell loss known to cause T2DM.

Thus, differences in dose and duration of treatment with SS-31 in these models may be significant factors in the observed differences in outcome.

It may be significant that these two enzymes modify residues 46 and 48 of the extra loop of tRNA U U U L y s , implying a functional interaction between the two modifications in this region.

The frequent co-occurrence of PIK3CA variations may be significant in determining targeted treatment strategies for NSCLC.

Hypothesis 2: There may be significant associations between common psychological health disorders .