“may be significant”

Once osteoporosis is present, there may be significant pain and deformities, which also increase morbidity and mortality ( Lin and Lane, 2004 ; Uzzan et al., 2007 ; Pisani et al., 2016 ).

However, since the levels of proteolytically active KLK3 in extracellular fluid in the prostate can be as high as 2 μM [ 22 ] even a low activity may be significant.

Pro-oxidant activity may be important in vivo if free transition metal ions take part in oxidation processes and may be significant for certain metal excess diseases [ 252 ].

The scores of responses RSE 6, i.e., “I certainly feel useless at times” in the age range of 10–15 years may be significant due to the reason that many a time the UCLP patients may have a feeling of worthlessness.

This observation indicates that genetic factors may be significant in the occurrence of oesophageal cancer; however, the molecular basis for susceptibility to this disease remains unclear.

This suggests there may be significant interspecies differences in the organization, and perhaps the function, of the EVS.

This anti-inflammatory effect may be significant for the prevention and improvement of metabolic diseases such as obesity and diabetes.

Yet, if particle-attached NCD N 2 fixation is light independent, these low putative cell-specific rates and abundances may be significant when depth-integrated, considering the large expanse of the dark ocean 37 , 60 – 62 .

Since the most economical heat-recovery systems require high-temperature carrier fluids, the thermal shocks may be significant.

When the BWE in maize is at its peak of 7 mm, a 0.5–2 mm addition of intercepted water may be significant and detectable within the overall noise.

On top, the intangible costs for victims may be significant, encompassing emotional distress, social consequences, and stigmatization.

The balance between host methylation of dopamine to form 3MT and bacterial O ‐demethylation of 3MT to form dopamine may be significant to the regulation of dopamine levels outside the brain.

The epigenetics and epigenomics may be significant for crop adaptability and pliability to ambient alterations, directing to the creation of stout climate-resilient elegant crop cultivars.

Predictors of anti-TB ALF Univariate logistic regression analysis suggested that laboratory values at the time of DILI recognition, including transaminases, TBL, direct bilirubin, ALP, hemoglobin, platelets, albumin, and white blood cell count (WBC), as well as pre-existing hepatitis, symptoms (abdominal distension, nausea, vomiting, itching), ascites, and jaundice may be significant risk factors for the development of ALF during anti-TB treatment ( Table 3 ).

In the particular case of ferroelectrics, differences between local and long-range ordering may be significant.

However, only a small fraction of the present cohort reported recent contact with standing water or rodents, which suggests that less overt exposure routes may be significant, or indirect means of exposure to the pathogen may be ignored or go unnoticed.

Therefore, the result in Figure 2B may be significant, since the Tm-shift was observed only when the CA-polymerization could occur.

Nonetheless, small mammals, toads and lizards also feed on adult butterflies, and there may be significant predation by a variety of invertebrates (Londt, 1999 ).

In this case, the knowledge of this rare mutation may be significant in guiding a therapeutic decision and to explain potential resistance to anti-EGFR antibodies.

While the averaging effect over a number of fractions counteracts the interplay-effect and produces a comparably good PTV coverage in total, the dose difference between single fractions may be significant [24] , [39] ; whether this is biologically equivalent to a treatment plan with identical fractions is uncertain.

rary oral surgical practice and requires much planning and surgical skill, during both preoperative diagnosis and postoperative management.[ 1 ] Although the overall complication rate is low and most complications are minor; this procedure is so common that the population morbidity of complications may be significant.[ 2 ] It is important that a paradigm for factors associated with third molar extraction difficulty be developed to serve patients more effectively, to plan operations, and to educate students and residents.[ 1 ] Wharfe, Winters lines, and Pell and Gregory classification are the well-known classifi

Risk Factors for Infection Chemotherapy and/or radiation therapy may be significant factors contributing to the development of post-operative infections in this group of patients.

Psychiatric institutions may be significant contributors to the local economies of isolated communities, as is the case in former Soviet Republics, which means closing or downsizing them would dim the employment prospects of staff and instigate other negative consequences on the local economy [ 88 , 164 ].

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shedding through the gastrointestinal tract leads to epithelial barrier damage, immune activation, changes in microbiota composition, dysregulation of the serotonin pathway, and intestinal neuropathy, which may be significant factors contributing to the high incidence of IBS in patients during acute infection and postrecovery [ 42 ].

It is not known whether there may be significant clinical differences in the vascular effects of different ARB or BB drugs in this situation, or whether any benefit is a class effect.