“may be significant”

Further analysis should include other genetic factors besides APOE ε4 that may be significant to cognitive decline, and ADNI genetic data are now becoming available.

Secondly, there may be significant heterogeneity observed across studies.

Whole exome sequencing of this patient’s tumor identified missense mutations in the mTOR and FGFR2 genes, which may be significant due to nucleolin’s function in augmenting mTOR pathway activity through AKT1 mRNA translation.

The emergence of multiple drug resistance among Staphylococcus aureus isolates may be significant, though the exact prevalence and clinical implications remain to be known. 3.3.

Experiences in one’s family of origin in particular may be significant in shaping storage behaviors.

This may be significant, considering that it is more difficult to treat the symptoms of attention deficit in clinical practice and that symptom improvements are associated with functional improvement ( 27 ).

In this previous PM study, the nose was selected as one of the most useful features, but our study suggests that there may be significant changes to nasal tip shape due to pressure caused by a body bag.

Response to frontline treatments may be significant initially but short-lived with a dismal median overall survival below one year.

Conclusions Collectively, our findings are consistent with the view that gene fusions and other SVs may be significant factors in the onset and progression of ovarian cancer.

E-cigarettes and hookah are often marketed as safer alternatives to traditional cigarettes [ 2 ], but emerging evidence suggests that their health risks, particularly among young and impressionable populations, may be significant [ 13 , 14 ].

It may be significant that the glutamine residue at position 6 would be the first residue of the coiled coil, following the disruption caused by the preceding proline and charged residues.

Conclusion The restorative benefits of tDCS can be critical to understanding the cause-effect relationship between certain neural circuits and behavioral outcomes, which may be significant in illuminating the early pathophysiology of AD and PD.

Since there may be significant differences in data sharing among enterprises in different industries, the research results may still have some deviations.

Furthermore, only a small subset of patients had no sleep concerns—there may be significant differences in sleep architecture between sleep diagnostic groups that this sample size could not detect.

If SWS is reduced because of the conditions of spaceflight or displaced by REM recovery over long‐term chronic sleep loss, there may be significant consequences for those who live and work in space for long periods; for example, such sleep losses have been correlated with an increased risk of dementia (Nedergaard & Goldman, 2020 ).

Later results suggest that fatigue resistance and muscle stiffness of the hamstring muscles may be significant risk factors for sustaining an ACL injury [ 18 ].

While the denitrification enzymes are also important for detoxification [ 126 ], the use of nitrogen compounds as electron acceptor may be significant in methane oxidation [ 127 ].

The main finding of our study was that the antibacterial effect of fluoride may be significant both in preventing initial carious lesions and in enhancing the remineralisation capacity. 16 Comparison of caries status based on changes in caries risk scores proved that more favourable findings were obtained for children who received FV than for those who received FMR or no fluoride application.

The impact of utilization of local reference ranges may be significant in reducing screening to enrollment ratios in clinical trials.

In addition, there may be significant differences in metabolomic characteristics between ethnic groups, which may be due to differences in genetics, diet, culture, or gut microbes.

As seen in the selected GeneGo network, our overlapping Gene2MeSH candidates anchor the network and provide a means of identifying interactions that may be significant in disease, but other genes in the network are also viable candidates.

Altogether the cynic may consider these issues as semantics – these seemingly minor technical points may be significant in terms of reported epidemiology of AKI, as well as coding practices for reimbursement.

Based on the reports mentioned above, there may be significant maternal and reciprocal effects for root biomass allocation and other traits of interest in wheat.

Nevertheless, the findings may be significant for the practical implementation of compression garments.

Naturally, we suspect that there may be significant heterogeneity in Npas4 expression dynamics across the POMC population as well.