“may be significant”

Given the prevalence of chronic gastroesophageal reflux in this cohort, we believe the association between this acidity and GAW may be significant.

Hemorrhage may be significant in the cerebellum, brainstem, rhombencephalon, and mesencephalon and may result in fatal infarcts ( Jacoby et al., 1987 ).

thaliana , and species-specific differences in the response of photosynthesis genes may be significant, even between grass species ( Kümpers et al., 2017 ).

The biological function of these microRNAs in ASD pathogenesis remains little known, and there remains a question as to which miRNAs may be significant specific signatures as personalized biomarkers or therapeutic targets.

In silico analysis of POR amino acid variants Multiple sequence alignments of dog POR with homologs from other species showed that the 315 glutamate residue was largely conserved, indicating that this residue may be significant to the structure or function of the protein ( Fig 1A ).

These drinking‐related changes in nociceptive sensitivity may be significant for binge drinkers and individuals with AUD.

The impact of this mutation on Kawasaki disease remains unclear, though its role in this patient’s refractory course, sequelae, and early calcification may be significant.

MiR-181a's modulation of the PDCD4-BID apoptotic pathway during ischemia and anoxic conditions may be significant in reducing the effect of pathological damage to the heart after MI.

Additionally, there may be significant correlations between Eaton-Glickel radiographic stage and PROMs that we were unable to detect with our sample sizes.

However, that study had a significant methodological limitation in that we had allowed a 30-day interval between the CE study and FC measurement [ 7 ]; while relatively short, this time-gap may be significant due to subtle and spontaneous changes in the degree of active SB inflammation [ 18 ].

Our results show that STV-Na reduced the area of colonic erosion, a finding that may be significant with regard to iron metabolism or ferroptosis homeostasis.

These findings suggest that the regulatory mechanism of ceRNA may be significant in the upregulation of Acin1 and possibly contribute to its fine-tuned regulation.

The overlap between malnutrition and sarcopenia may be significant [ 23 , 24 ]; for example, in a recent meta-analysis of pooled data from 7 studies of hospitalized older adults, the odds ratio (OR) for malnutrition among sarcopenic patients was 4.06 (95% CI: 2.43, 6.80) [ 25 ].

KIR genes display extraordinary level of polymorphism and diversity among different populations because of which there may be significant differences in ligand affinity or signal transduction.

29 ) The presence of both non-phosphorylated (NAD + and NADH) and phosphorylated (NADP + and NADPH) forms may be significant in making it possible for several kinds of redox reactions to co-exist in a cell and/or to control traffic of metabolic pathways. 30 ) NAD kinase is the sole NADP + biosynthetic enzyme and catalyzes the phosphorylation of NAD + to NADP + in the presence of ATP (ATP-NAD kinase: NAD + + ATP → NADP + + ADP) (Fig. 1 A).

Lower concentrations may be significant in chronic infections or in females.

Recent investigations into the echeneid-host association also suggest that there may be significant costs incurred by the host, such as persistent damage and scarring from the adhesive disc by which the remoras attach themselves to their hosts, as well as deforming injuries when smaller-sized remoras force themselves through the gill slits and other body openings of their mobulid host [ 15 , 23 , 59 ].

This data may be significant for future comparative studies.

Abstract Background Work organization and psychosocial factors influencing sleep patterns may be significant risk factors for developing obesity and metabolic syndrome (MetS).

Discussion This risk assessment found that some e-cigarettes may be significant sources of metal exposures, capable of increasing the risk of cancer and non-cancer respiratory and CNS health effects.

In addition, there may be significant inter-individual variation in the accepted thresholds for stroke prevention at the cost of additional bleeding events.

Therefore, in addition to these reported mechanisms by which estradiol and testosterone may play a prognostic role for peri- and post-menopausal women, the current findings suggest that the abrupt loss of estradiol at menopause and the potential increase in total testosterone may be significant contributors to left atrioventricular coupling.

Due to the different living environments, tissue aging rate, and health status of individuals, there may be significant differences in the aging status group of individuals with the same actual age.

Clarifying the state of SMID patients in this study may be significant.

Inactivation of Notch signaling and expression of ASCL1 may be significant for SCLC carcinogenesis.