“may be significant”

Fever has been associated with improved survival rates during typical complications ( 2 ) and may be significant at early stages of infection as well.

The tissue-residential distribution and the proinflammatory property may be significant for making NKB cells and IL-18 unique targets in the development of immunotherapeutics for periodontitis.

However, the electrostatic effect may be significant if the linker was short as in the case of H 2 NCH 2 -γ-PNA whereby the duplex stability was higher than in the case of the amino-modified γPNA with longer linkers ( Table 5 ). 48,50,51 Interestingly, γPNA with the negatively charged –CH 2 SO 3 − substituent adopted a more extended conformation in the single-stranded form as shown by NMR and CD analyses which could be due to the intra-strand electrostatic and steric interactions among the sulfate groups.

By pushing speakers towards the media, a company’s influence over science communication may be significant and therefore should be fully disclosed ( 2 ) .

It has been suggested that genotoxic damage may also contribute to the formation of common, age-related cataracts and, in that regard, it may be significant that micronuclei, biomarkers of DNA damage, are present in epithelial cells from cataractous lenses. 35 Until recently, however, sequencing methods have lacked the sensitivity to determine directly whether somatic variants are present in the human lens.

Understanding the interactions between innate and adaptive immune responses may be significant for the development of an efficient prophylactic vaccine, which would stimulate protective immunity and limit transmission of infection [ 42 , 45 ].

Nevertheless, this study suggests, in general terms, that there may be significant benefits to carers from enhancing their choice on entry to a caring role.

In fact, if a spatial dataset is not big, there may be significant errors between the calculation results of Moran’s index and the I * values.

This skeletal involvement may be significant in the annotation of SD, metabolic bone diseases, dysostoses, and bones malformations, limb deficiencies. 2.

Font comparison A simple way of measuring font legibility by calculating unweighted averages of A i values is not a good solution in real situations, as the font distribution of actual texts differs significantly from the uniform one; in addition, there may be significant differences in each language.

This may be significant as recent critiques of intersectionality charge the theory with losing its critical potential [ 38 , 39 ].

11 This finding may be significant in cystic fibrosis, where nebulized hypertonic saline solution (0.6 – 0.7% w/v NaCl) is employed as a mucolytic agent to improve mucociliary clearance of sputum from the CF lung.

The high cost involved in the CO 2 capture, transportation, and storage may be significant enough to discourage investments, which can also result in elevated technical barriers for the implementation of BECCUS projects, especially in regions with limited access to resources [ 178 ].

This is in line with the statements that among individuals with a lack of genetic risk for hypertension, the protective role of psychological factors may be significant [ 28 ].

These levels of hemolysis suggest that these antibiotics could be administered intravenously at concentrations 10–20 times the MIC values without exhibiting significant hemolytic activity. Nevertheless, the greater hemolytic activity of the cyclohexylalanine analogues over d -Thr 5 -clovibactin suggests that both antibiotic activity and hemolytic activity increase with increased hydrophobicity and their nonspecific interactions with lipid bilayer membranes may be significant.

Moreover, there may be significant differences in text style and structure in different fields, which poses a challenge to the model's generalization ability.

The C2 dorsal listhesis while minimal in some cases may be significant in many cases and cannot reduce unless an additional ventral ‘push’ is provided to C2.

Some studies suggest that PFNET, which is originally developed to depict the salient network consisting of “concepts”, is more suited to knowledge structuring [ 24 , 25 , 26 ] because MST has the potential to eliminate links that may be significant.

By performing computer simulations, as well as experiments, Nell and Myers (7) determined that even if the focal spot is targeted more than 4 cm from bone, heating at the interface may be significant.

In older adults and individu- als (both young persons and older adults) with a compromised renal function due to illness, the half-life of domoic acid could increase sufficiently so that repeated expo- sure over 12 or 24 hr may be significant.

Consequently, there may be significant value to the implementation of intervention programs that recognize adults as parents and interactions with parenting stress and addictive processes.

Thus, more in-depth studies at a local level are required to complement aggregate statistics, particularly because there may be significant variation between areas.

As a result, it is anticipated that tumor-infiltrating immune/inflammatory cells may be significant hallmarks for immune monitoring of baseline peripheral blood in both treated and non-treated patients after resection ( 44 ).

However the findings of tumor-infiltrated Tph that do not secrete IL-21 but instead recruit Breg cells by providing TGF-β and PD-L1 challenges this unified view ( 138 ), these cells may not have the same origin with Tph in inflammary tissues, but it is also rational to reason that it is within the tumor microenvironment that Tph changes its state or become a new subset, and it could be valuable to compare this Tph with “bona-fide” Tph on the a larger panel of Tph signatures, tracking how Tph enter these pathogenic tissues may be significant in further illustrating Tfh and Tph relationship. 3.2.

Nonetheless, a modest impact on TNFα production may be significant, as positive feedback loops leading to enhanced TNFα production might amplify the impact of this SNP in vivo [33] .