The effect of Dam methylation on gut colonization and survival may be significant.
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The judicial arrangements may be significant.
Among the thousands of proteins and peptides present in a serum sample, which represent its proteome, few key signals may be significant markers of the pathological state, and their search within the proteome represents a still open field of research.
In such circumstances, there may be significant organisational pressure not to intervene, with individuals having insufficient power to raise concerns without some risk of negative personal consequences.
Linked to this, the spread of participants’ countries represents a diverse spread of healthcare systems and demands, and it is vital to recognise that there may be significant variations in the work experiences across countries [ 52 ].
Hence, increasing the number of respondents may be significant in multivariate analysis.
In conclusion, an increase in exposure time may be significant up to a threshold, in this case, at 100 minutes for 5 ppm and 50 minutes for 0.5 ppm and 2 ppm, after which increase in exposure time may not have any appreciable reduction in viability.
However, the bias may be significant but not sufficiently large so, in addition, we measured the proportion of obtained essential genes with a negative Aquilles-based score in each scenario, a point where the probability of the gene being essential is higher than being non-essential.
Thus, the contribution of 21q loss may be significant for the clinical findings, as well.
This indicates that the expression of sB7-H3 and sB7-H1 may be significant in the CSF, but not in the blood serum in patients with glioma.
Intense CAS may be significant enough to impede blood flow and cause myocardial ischemia.
Understanding the local-level context is important because local-level changes (e.g., deforestation or overgrown farmlands) may be significant as they affect an area’s scenic and recreational value but may not be relevant at the regional level.
Furthermore, the timing of impact assessment is an issue as there may be significant time lags to a policy change.
Considering the accumulated line of evidence on the associations of SB and PA with health benefits [ 20 , 21 , 22 , 45 , 46 , 47 , 48 , 49 ], differences in the time spent in SB and PA between drivers and non-drivers may be significant.
Its relevance may be significant, since interneurons migrate from specific progenitor domains to populate cortical and other regions during brain development.
In light of this conclusion, one implication is that the current estimates of cholera disease burden that are based on culture-confirmed cholera may be significant underestimates, and that a reassessment of past and recent cholera studies may be needed to guide public health policy on cholera control measures in countries affected by cholera.
Significant difference found between the study groups for procalcitonin and white blood cell count could suggest that simultaneous determination of these two parameters may be significant for the diagnosis of bacterial infection.
There may be significant differences in microbial composition between the intestinal mucosa and feces [ 46 , 47 ], which may allow for distinction in the microbial composition among fecal, fluid, and biopsy samples [ 46 ].
It may be significant that a proportion of patients with bad prognosis on the basis of their tumour histology showed consistently negative results.
From our current data, we speculate that there may be significant differences in the immune function of skin with different appendage types, and that the occurrence of spines may be an innovative physical protection for dorsal skin with relatively low immunity.
As a result, understanding study limitations may be significant in interpreting and applying the findings.
Thus, while the overlap among these databases in terms of peptide sequences may be significant, the overlap in terms of the published and derived metadata made accessible to the end-user is much smaller.
In particular, the prevalence of PH-HFpEF within the SSc population with PH (SSc-PH-HFpEF) may be significant, in the range of 20–45% in recent studies. 6 , 7 Several studies have previously shown that SSc-PAH is a distinctive entity within Group 1 diseases.
Moreover, as specified by miRDB: the microRNA database, BCL2, LMO3, PTEN, SNAI2, WIF1 are also molecular targets of miR-630 and may be significant in NSCLC progression [ 19 ].
The cooperative motions of the Site3 GlcNAc and the Phe410 side chain may be significant from the mechanistic viewpoint.