Barely Significant
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“may be significant”

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In the literature

However, in cases where children present with persistent microscopic haematuria often accompanied by episodes of visible blood in the urine (gross hematuria), there may be significant anxiety for both patients and their families, leading to a strong desire for a definitive diagnosis [ 28 ].
Alport Syndrome: A Comprehensive Review.
Cureus · 2023 · PMC10649250
Further investigation into the exact mechanisms through which concentrations of tacrolimus are impacted by the local microenvironment are needed, however, this preliminary evidence suggests that there may be significant benefit to determining optimal trough levels or potential targeted microbial repopulation to optimize recipient outcomes. 3.3.