In addition, not all purchased medicines are necessarily administered to a patient and there may be significant waste.
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In the literature
Together, these findings suggest that there may be significant value to a hybrid CSC delivery model being piloted by EPICENTER with funding from OhioMHAS, where some components of CSC for FEP are provided by the CMHC itself and others are administered by a centralized clinician team at a major medical center– linked by virtual team meetings.
The number of viruses in the atmosphere is uncertain but may be significant (Reche et al . 2018 ).
Discussion and Perspectives In sum, miRNA expression patterns in whole blood are mainly influenced by erythrocytes, and RBCs may be significant repositories of miRNAs in the circulatory system, playing potential roles in erythropoiesis and disease development.
It may be significant that both relative brain size and longevity are greater in the echidna than the platypus.
Considering the high incidence of vitamin D deficiency in subjects with TD, screening and proper interventions for VitD may be significant for TD.
This is, however, no major problem, as stochastic external factors associated with climatic and weather conditions in urban or rural environments may be significant for certain drone missions [ 28 ].
Nevertheless, this suggests that there may be significant differences in host preference among different B. abortus clades.
This approach is congruent with our intention to contextualise end-of-life experiences for the deceased and bereaved within a broad socio-cultural, political and historical context; for Māori, we anticipate the impact of cultural disenfranchisement, urbanisation, and discrimination may be significant here [ 23 ].
Whilst our data are based on observational findings in a relatively small number of samples, and take no account of possible partial- or non-adherence to medication, the higher clozapine concentrations and the higher clozapine:norclozapine ratio may be significant factors determining the increased incidence of weight gain and dysmetabolic profiles in females prescribed clozapine.
This suggests that there may be significant differences in baseline between age and menopausal status, potentially due to hormones such as estrogen, that require further investigation.
For breast cancer in mothers, baseline rates of any breastfeeding at 6 months after birth were used, as evidence suggests that the effect of breastfeeding on the incidence of breast cancer may be significant from 6 months of breastfeeding onwards [ 17 , 18 ].
This is also the first report to present an ABPA case with the relationship between serum CEA level and eosinophils count, and our findings may be significant for clinicians.
We hypothesized that there may be significant regional variations in imaging practice despite best-practice recommendations.
trachomatis infection may be significant cofactors associated with persistent HPV infections.
This finding may be significant in the pathogenesis of stromal ulceration, where the upregulation of matrix synthesis might occur in response to tissue destruction.
In line with this, lived experiences of individuals suffering from burnout reveal that "the significance of past, present, and future is changed," and that their intentional direction appeared to be pointing ‘backwards’ in time rather than ‘forwards’, which may be significant for the process of recovery (Engebretsen & Bjorbækmo 2020b , p. 1475).
Furthermore, the ability of RAP to bind Aβ and act independently of LRP1 is supported by previous animal studies showing RAP deficiency does not significantly affect the levels of LRP1 (Xu et al., 2008 ), suggesting that either a relatively modest change in LRP1 may be significant enough to cause changes in Aβ deposition or RAP possesses an ability to affect Aβ independently of LRP1 (Xu et al., 2008 ).
The fact that we found significant deficits in attention and problem solving suggests the possibility that even minor elevations in TSH may be significant.
The results presented in this study indicated that the anticancer effect of celecoxib is selective in colon cancer cells; celecoxib may target cancer cells via the SMO-independent modulation of GLI1 activity, and Hh signaling may be significant in maintaining the malignant state of LoVo cells.
Therefore, even though there may be significant contextual differences of constituting elements, home remains the locus of social and personal experience, formed by a special brand of interrelationship among people and places linked to them.
This possible communication channel may be significant for enhancement of differences between lineages and adaptation.
Therefore, whether or not AMIs are administered in a research context may be significant.
Serum contains a great number of proteins; the interaction of cucurbiturils with these proteins may be significant for hemolytic activity.
Development of intervention method on orexin system by different administration routes especially for injected opiate addicts at detoxification phase may be significant and was welcome. pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc-prop-has-pdf yes pmc-prop-has-supplement no pmc-prop-pdf-only no pmc-prop-suppress-copyright no pmc-prop-is-real-version no pmc-prop-is-scanned-article no pmc-prop-preprint no pmc-prop-in-epmc yes pmc-license-ref CC BY 1.