“may be significant”

While the relative amount of internal mediators is low, their biological effect may be significant as vesicles can deliver these mediators to the very vicinity of the target cells.

As exemplified above in α-cells, changes in other cell types within islets may be significant, and possibly primary, via their interactions with pancreatic β-cells.

Moreover, the prolonged incubation period in kuru (over 50 years in some cases) may be significant when attempting to estimate future numbers of vCJD.

In patients with large intrathoracic goiters, difficulty breathing on exertion and diaphragm elevation on chest X-ray may be significant findings predicting future respiratory failure.

Why Is Nodal Signalling Higher in Dorsal Positions? At 5 hpf, the expression of sqt and cyc is uniform throughout the margin of the zebrafish embryo [ 13 ], so what might cause the activation of Smad signalling to be higher in dorsal regions? Evidence suggests that the duration of signalling as well as the concentration of the morphogen may determine cell fate [ 17 , 33 , 34 ], and it may be significant that expression of sqt both commences on the dorsal side of the embryo and persists for longer in this region [ 13 ].

Significance of the pairwise t-tests is strongly dependent on the number of isolates of each species sampled, so the groupings shown in Table 5 do not simply change with the magnitude of the difference of the means; a large difference may not be significant if there are small sample sizes for both species while a smaller difference may be significant.

Our current and other previously published findings suggest that lobule VI is critical for motor tasks and altered structure and function may be significant predictors for DCD symptomology ( Zwicker et al., 2011 ; Biotteau et al., 2016 ; Debrabant et al., 2016 ).

The size of the SC in the nasal and temporal regions may be significant in our study.

The authors pointed out that psychological health, social support, and the degree of control prior to the intervention may be significant factors in determining those who benefit compared with those who do not. 82 Cognitive behavioral therapy (CBT) has been used successfully in patients with chronic neuropathic pain conditions. 84 – 86 In particular, a case series by Tichelaar and colleagues involving three patients with complex regi

Conclusion: Using this integrative approach, our study identified prominent transcriptional biomarkers which may be significant targets for OC therapy.

Although, in general, there is a major improvement between the age of 1 and 2 years, with only a minority still having feeding problems after the age of 2 years, as long as the feeding problems continue, the impact on the quality of life of both NS infants and their caregivers may be significant.

Considering that scientific information on physical activity determinants in rural populations are scarce, the study will naturally contribute to the literature; and (4) follow-up starting right after a public health crisis that has had considerable impact on various aspects of people’s lives worldwide, including lifestyle and work conditions, may be significant, given that recent studies have shown worsening indicators of both lifestyle and occupational health [ 21 , 22 ].

It is of interest to note that this particular reduction may be significant as several species belonging to this genus have shown to interfere in the growth of pathogenic bacteria in the upper respiratory tract [ 25 ].

The ISO 6603-2 low-velocity impact test methodology should be employed with caution for brittle materials since the kinetic energy of the specimen (and fragments thereof) as the specimen fails may be significant relative to the internal energy.

Our findings may be significant for the identification of PE in LC patients at an early stage.

The difference in surgical and medical management of type A aortic dissection among the 3 institutions may be significant.

In terms of changing behavior in skin cancer survivors, family members of melanoma survivors, and parents who suntan and put their children at elevated risk, there may be significant challenges in translating knowledge into behavior given social and media influences.

The changes involve both inducible NOS2 and endothelial NOS3, indicating that both enzymes may be significant sources of NO within the endometrial tissue.

The R-gene expression was up-regulated in the resistant genotype ZC108 compared to the susceptible host, which may be significant for effector-triggered immunity (ETI).

Therefore, there may be significant differences in the impact of fertility on the health of women whose households are registered in different regions.

It may be significant that LOX-1, with essentially no sequence similarity to SRECI associates with TLR2 after ligand binding and mediates immune responses in a similar way to SRECI (Jeannin et al., 2005 ).

Distances in PySSED come from different methods, not only parallaxes from Gaia, and even if distances came only from Gaia there may be significant errors or biases coming from the parallax uncertainties.

Although there are no significant differences between the three subgroups analyzed, may be significant differences between men and women.

Therefore, we hypothesize that the specific accumulation of these metabolites may be significant both biologically and evolutionarily in the differentiation of indica and japonica accessions, as well as their adaptation to environmental stresses.

If the model fits well, it indicates that there may be significant common method bias.