Barely Significant
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“may be significant”

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Two previous studies have also suggested that pain-symptom descriptors may be significant predictors of NeP severity. 28 , 29 In those studies, the presence of a higher number of descriptors, as well as specific descriptor qualities, had greater predictive value for more severe pain. 28 , 29 The range of descriptors constituting painDETECT overlaps with those descriptors that have shown predictive ability for pain severity.
Measurement properties of painDETECT by average pain severity.
Clinicoecon Outcomes Res · 2014 · PMC4226388
As non-coding RNAs have key biological roles (rRNA, tRNA etc), may be significant in terms of adaptive processes and are useful for genome annotation we also provide the unfiltered transcripts (includes those not passing ORF filters, but meeting support and expression thresholds and those with ORFs not meeting expression thresholds) in the associated data repository 13 .
4 , 5 Although a clear conclusion could not be drawn from this sequence of events, the temporal association between physical trauma and the onset of RA has been reported previously and may be significant. 6 The spontaneous spread of CRPS, without new trauma, is a well-known phenomenon possibly mediated by spinal or supraspinal mechanisms. 7 The spread of vasomotor symptoms occurred in most of the patients studied.
However, of importance for the implementation of control programmes in Africa, it has been suggested that analysis of gene variants of HLA-DRA and the HLA-DRA|HLA-DRB5 inter-region, which may be significant predictors of allergy to penicillin, should occur in African populations. 34 The role of genetic studies ARF and RHD are caused by a combination of immune, environmental and genetic factors.
Should this be a cause for concern, and how low must the maternal mtDNA carry-over be in order to consider these therapies successful? These questions will be difficult to address experimentally because current animal models of mtDNA disease do not closely resemble human disorders ( Nakada and Hayashi , 2011 ) and there may be significant differences in the mechanism of mtDNA transmission (i.e. the mtDNA bottleneck) between humans and mice ( Wonnapinij et al ., 2010 ).