“may be significant”

This level of uncertainty may be significant, as previous studies have shown that typical minimum clearance ranges from 11 to 15 mm 32 .

Specifically, the determination of amino acid profiles in patients with COVID-19 may be significant for developing different treatment strategies.

Therefore, research on PGM1 and whether it targets the PI3K/AKT pathway may be significant for the management of CRC.

Some recent reports have confirmed that contaminated vegetables may be significant contributors to the total dietary PTE intake, particularly in terms of Cd, As, and Pb 25 , 55 , 64 .

For microflow configurations, it is advisable to avoid transferring a single analyte plug from the trapping column with a strong solvent, as the volume of such a plug may be significant in comparison to the volume of the analytical column, potentially causing breakthrough.

Our results, as well as previous studies [ 41 ], support the hypothesis that SFA may be significant in the etiology of LC and deterministic in its development.

Therefore, it appears that the effect of chromosome 18 on differentiation of somatic cells during the developmental stage may be significant.

Conclusion The identification and characterization of the interaction of BRCA1 with PP1 and detection of changes in the expression of PP1 and genes encoding other BRCA1 associated proteins identifies important genetic pathways that may be significant to breast tumorigenesis.

For example, if 50% of care initiations are in the private sector but only 10% of case notifications come from the private sector, there may be significant dropout along the care-seeking pathway after care initiation in the private sector.

In the Hp ParAD41A–DNA– Hp ParBN10 complex, the corresponding residue of Arg19 is conserved Arg9 in Hp ParBN10, which interacts with Hp ParAD41A Phe52 through a novel cation–π interaction which may be significant for Hp ParA and Hp ParB interaction.

However, there may be significant discordance (25%) among radiologists when assessing small subsegmental contrast filling defects.

Second, while resolvers share the ability to reduce the expression of many typical fibrosis-associated genes in established myofibroblasts—such as α-SMA and ECM constituents—their complete spectrum of elicited transcriptomic and/or functional changes may differ in ways that may be significant.

Whereas undesired reductions in MHC variability may not directly impact productivity, long-term consequences for animal and human health may be significant ( Alexander, 2007 ).

The nodularity and lumpiness that accompany FCD may interfere with the correct detection of breast masses, and mastalgia may be significant enough to affect the patient’s activities and quality of life or cause concern and worry about breast health.

Gemcitabine, Paclitaxel, Carboplatin, Avastin etc.) and other treatment modalities such as radiation, radionuclide therapy and immunotherapy may be significant contribution to cancer research.

Quantitative Ca and N may be significant for the yield and biological activity of cultivated P . tenuifolia .

It has been suggested that the timing may be significant because the development of the fetal immune system is affected differently depending on gestational stage [ 25 ].

The frontier molecular orbitals are frequently thought of as constructs that define modifications in the valence electron occupations upon reduction; however, there may be significant rearrangement in the orbital structure, in part arising from the geometric changes, for example, the Fe···Fe distances and the ∠Fe‐N‐O bond angle.

florus emerges from orchard hosts, so there may be significant parasitoid mortality during this period because of the absence of appropriate hosts.

83 In mice and rats, circulating bands are uncommon, and the degree of the inflammatory response is less pronounced; even mild increases in neutrophils may be significant in these species. 64 Thus, in small mammals, the presence of immature cells like bands and toxic changes or a change in the neutrophil/lymphocyte ratio are more reliable indicators of inflammation than the total WBC and differential counts. 11 Illness, handling, or trauma may cause a leukocytosis characterized by a neutrophilia and lymphopenia due to endogenous glucocorticoid release. 17 This may occur simultaneously with a compensated inflammatory response, making interpretation difficult.

For example, although total fish production in an ecosystem may be maintained, there may be significant and unpredictable switches in the species contributing.

The computational burden of the bootstrap approach may be significant in some cases, especially in large-scale studies or when computational resources are limited.

In addition to the cessation of symptoms, this may be significant in the future if leads are to be removed or the pacing system is expanded.

The higher radiation exposure in this LL position may be significant for patients expected to require multiple ERCPs, particularly pediatric patients, but is also relevant for staff and their long-term exposure to radiation.

Thus, even without the UTX mutations, anomalies affecting UTX expression levels such as haploinsufficiency and DNA methylation in the promoter region may be significant contributors to cancer formation 9 .