tion of nitric oxide (NO) and TNF-α.[ 13 ] This property affords antioxidant protection during I/R by both reducing the levels of NO and lowering the generation of peroxynitrite, another reactant easily capable of initiating lipid peroxidation.[ 30 , 32 ] These indirect antioxidant actions of α-MSH may be significant in affording protection against neuronal injury.[ 13 ] α-MSH is known to have the ability to modulate CNS inflammation.
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89 Though it is a small sample, the fact these critics were all men may be significant; research suggests that men feel less connection to the NHS and to matters of health more generally. 90 Finally, there were respondents who were aware of the anniversary but simply uninterested, explaining this on the basis that such celebrations were largely irrelevant to the real issue of protecting the service.
Yet there may be significant variation in the forms of transactional sex with main partners and transactional sex with casual partners.
For commercial re-use, please contact [email protected] Helix 42 of Domain II of Escherichia coli 23S ribosomal RNA underlies the L7/L12 stalk in the ribosome and may be significant in positioning this feature relative to the rest of the 50S ribosomal subunit.
Other vital signs and physiological status not included in NEWS such as frailty and mobility (Brabrand & Kellett, 2014 ) may be significant indicators of deterioration in the care home setting.
There may be significant differences among researchers in their outlooks regarding the substantial progress and future development of AI, among other enabling technologies.
In this context, we hypothesize that, although both phacoemulsification systems are safe and effective, there may be significant differences in intraoperative efficiency - particularly in terms of mean surgical time and ultrasound energy utilization - as well as postoperative outcomes.
cruzi in the lumen of the scent gland occurs without adhesion of the parasite and may be significant (involving up to 50% of the T. cruzi present), however the “vectorial” capacity of Didelphidae in natural conditions is still unknown ( Fig. 4 ) [ 23 ].
Increasing evidence has indicated that circRNAs modulate multiple physiological and pathological processes, including cell survival, proliferation, metastasis, tumorigenesis and tumor progression, and may be significant biomarkers in cancers ( 40 , 41 ).
The researchers suggested that the 5′ terminal conserved region of influenza A virus RNA segments may be significant in the study of potential drugs for preventing and controlling influenza virus infection [ 100 ].
Importantly, there may be significant overlap between existing medical conditions and POTS.[ 5 , 9 , 11 , 12 ] Discussion of various POTS associations and subtypes, along with current therapies and treatments, is the subject of this review.
The loss of VE Cadherin in baseline scleroderma and the reappearance of VE cadherin after HDIT/HCT may be significant in terms of the angiogenic potential of the skin, since the same 5 patients whose VE cadherin expression returned to normal also increased the numbers of capillaries present in their skin.
Depending on the application, this computational overhead may be significant enough.
Furthermore, the volume of reagents needed is small so that little absorbing antigen is re- quired. The degree of antigenic variation, noted to be greater with the first of the two antisera obtained from the human volunteer, may be significant.
Neuronal degeneration and activation of caspase 3 observed in this study supports this notion and indicates non-reversible neuronal injury may be significant to individuals suffering from PASC.
Given the different microarray platforms, analytic techniques, and reporting strategies employed in the different studies negative results from this comparison should be interpreted cautiously (the failure of a gene to be reported as being differentially expressed in multiple studies does not indicate that the gene is not in fact differentially expressed in RCC), but agreement across multiple papers may be significant – especially given the differences between the studies.
Previous studies have shown that distinguishing specific subtypes of IA is also a valuable research perspective, as predisposition factors may vary by IA types (e.g., there may be significant gender differences between online game addiction and social media addiction [ 75 , 76 ].
Local changes in small areas in metal levels in the feathers of raptors may be significant and not adequate 33 , while aquatic birds will rather reflect water pollution 27 , 34 , 35 , there are few studies on sedentary species leading a forest and field lifestyle.
On the other hand, a span of molecular weights of commercially available biopolymer samples, challenging chemistry, limited or lack of solubility in organic solvents, and, in some cases, slow enzymatic degradation may be significant drawbacks when considering polysaccharides as payload carriers.
Surgical microvascular decompression has been reported to offer long-term relief in up to 95% of treated patients ( Chung et al 2001 ), but there may be significant morbidity and mortality from invasive intracranial procedures.
While these problems may be significant in a linear, parametric modeling context, the approach outlined here is more robust to these types of problems due to the flexible way in which model covariates can interact and influence one another.
Furthermore, HACE1-depletion leads to enhanced cell migration, which may be significant for malignant conversion ( Castillo-Lluva et al., 2012 ).
Depending on drawing parameters, e.g., draw ratio and temperature, the increase in tensile strength and elastic modulus of PP fibers may be significant, i.e., from 2 to 10 times higher [ 2 , 3 ].
Each has a strong self-evaluative component as well as an “other” evaluative component; and for each there may be significant consequences related to performance failure.
First, the studied group was composed of female soccer player from both first (n = 22) and second division (n = 46) and there may be significant differences in reported physical abilities across levels of play for female soccer players, as has been recently reviewed [ 73 ].