“may be significant”

Therefore, high short-term fluctuations in glucose levels, especially postprandial ones, may be significant in the occurrence of cardiovascular events by inducing endothelial dysfunction, inflammatory reactions, and oxidative stress which may lead to atherosclerosis [ 7 ].

The underreporting of this type of adverse event may be significant, given the fear or shame that may exist in reporting [ 15 , 32 , 33 ].

Differences in mesophase morphology may be significant for targeted application such as catalysis, separation, internal surface modification and bioimmobilization.

Urban mapping may be significant in promoting physical exercise and improving mental well-being by providing information for projects that increase park accessibility.

Thus far, it can be postulated that the reciprocal promotion among the breakdown of the inner BRB, infiltration of peripheral immune cells, and immune responses mediated by innate immune cells may be significant causes of the exacerbation of neuroinflammation early following acute glaucomatous injury.

If a very large sample is taken and it has a very small spread, even a minute difference between two groups may be significant, but it may not be practically relevant.

First, given that the VTA is located in close proximity to the Mn 2+ injection site, the amount of Mn 2+ transported along the myelin sheath of nerve tract via passive diffusion may be significant and independent of axonal integrity.

sikapusi is hunted and consumed as a source of protein, the risk of transmission to humans may be significant.

We also note that the presence of the zinc finger motif in SP1 may be significant in view of findings that the motif has been selected out from phage libraries to bind to quadruplex DNAs ( 29–31 ), and that transcription factors containing zinc fingers have been reported to bind to G-tract promoter sequences, notably the insulin promoter factor Pur-1/MAZ ( 32 ).

Similarly, the identification the loss of a gene cluster involved in polysaccharide synthesis may be significant but would need some minimal demonstration comparisons with patient sera and even API data that could support the presumption this might influence reduced virulence of the ST1005 isolate.

While the station effects may be significant as a whole for all rodent species, we also wanted to compare whether there was a fixed pattern to risk distribution each species associated with each station.

There are some compelling biological reasons why there may be significant sex-related differences in the therapeutic responsiveness of inhaled drugs in COPD.

Therefore, in the absence of any comparable quality of evidence on what makes psychiatric wards safer places, we recommend that the Safewards interventions are implemented on adult acute mental health wards, as the findings of this trial are that the gains for patients and staff may be significant.

This suggests that insufficient dietary folic acid intake and impaired MTHFR activity may be significant risk factors for the development of CVD.

After a longer period of time, there may be significant differences that are related to their self-discharge and different levels of charge resulting from uneven aging of the cells themselves.

These data support a model in which TLK1B alters the association of Asf1 with the H3–H4 dimer, which may be significant for the reformation of core tetramers, for example during reassembly of nucleosomes at the repaired junctions of a DSB [ 10 ], or in attenuation of transcription [ 21 ].

First, we cannot exclude that reporting bias on the outcome may be significant, for two reasons: (a) cancer diagnosis was self-reported rather than from cancer registries.

In addition, it should not be overlooked that BDNF levels are affected by lifestyle factors such as drug use, age, physical exercise, diet and stress, which may be significant for schizophrenia patients [ 38 ].

ELi corrects the calculation of EOA for the size of the ascending aorta, allowing for the phenomenon of pressure recovery, which may be significant in smaller-size patients [ 19 ].

We recognise there may be significant variation in experiences of nature-based pursuits depending on one’s degree of cognitive impairment which we did not seek to measure or control for.

The results of the current analysis suggest that there may be significant benefits with prompt initiation of agalsidase alfa after symptom onset and/or diagnosis of Fabry disease.

Second, due to the different doses of BBR, there may be significant heterogeneity here.

The association between COVID-19 and comorbidities such as obesity, diabetes and older age with outcomes suggests that metabolic disturbances may be significant [ 7 ].

This suggests that there may be significant scope for dementia risk reduction in this region.

Thus, even without the UTX mutations, anomalies affecting UTX expression levels such as haploinsufficiency and DNA methylation in the promoter region may be significant contributors to cancer formation 9 .