Barely Significant
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“markedly significant”

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In the literature

When low doses of rasagiline and idebenone were administered in combination, we observed that their joint effect on the neuroprotection and inhibition of the robustness of the signaling cascade was markedly significant and included a significant restoration of retinal thickness, enhancement of RGCs survival, amelioration of cell apoptosis in GCLs, and improvement in visual function.
10 The long-term psychological and occupational effects were also reported to be markedly significant. 5 Evidence from systematic review on the impact of epidemics and pandemics to Middle East respiratory syndrome (MERS), Ebola and COVID-19 indicated that depressive symptoms were reported among 27.5%–50.7% and severe anxiety symptoms in 45% of the HCWs.
Intranigral injection of AAV-hα-syn resulted in a markedly significant reduction of dopaminergic fibers, evidenced by a reduction of TH (Fig. 1a and f , Additional file 5 : Figure S1a) and DAT (Fig. 1b and f , Additional file 5 : Figure S1b) immunostaining, beginning at 1 week and reaching a plateau at 4 weeks, associated with progressive dopamine neuron death ranging from 50 % at 1 week to approximately 80 % at 16 weeks after surgery (Fig. 1d and f , Additional file 5 : Figure S1c).