“likely to be significant”

There are of course likely to be significant structural changes on target DNA binding – as observed recently for the type I-C complex ( 9 ), but there is also scope for the Cas3 subunit to play a role in these processes.

Last, the strong relationship between age and HAdV status, and the increased odds of bacterial coinfection with HAdV in younger children, is likely to be significant.

Given the small effects, the lack of real biological replicates, and the failure to apply standards set out by MIQE, none of these changes in gene expression due to FBL knockdown or EV71 infection are likely to be significant or real.

The wider psychosocial impact is also likely to be significant with increases in child and caregiver mental health problems in an already vulnerable group.

The decision to utilize one or two plates is most likely to be significant for patients near their skeletal maturity and ultimately needs to be balanced with the cost of an additional plate.

It was estimated that the mean cost savings for patients using telemedicine rather than in-person medicine were between $147.40 and $186.10 per visit.[ 10 ] This study did not consider cost savings of caregivers, which was also likely to be significant, as it is common for cancer patients to be accompanied by caregivers at their appointments.

After multidisciplinary clinical discussion, it was believed that the complex BCA dissection and stenosis was likely to be significant enough to cause his symptoms.

Taken together, mutations in these three signature pathways are likely to be significant contributors to the global miRNA downregulation found in MPM.

Both procedures reduce the dataset to a series of pertinent discussions likely to be significant for intragroup relations and group decision-making.

pneumophila [ 21 , 22 ]; however, there is also likely to be significant under-reporting of clinical cases due to the diagnostic testing undertaken.

Because the χ 2 test depends on sample size and is likely to be significant as the sample becomes larger, the ratio between χ 2 statistics and respective degrees of freedom (χ 2 /df) was additionally used.

While not assessed in our small pilot evaluation, there are likely to be significant economic, environmental, and personal benefits to such a program.

Each test yielded a p value which allowed us to sort features from smallest (most likely to be significant) to largest (least likely).

Future work might integrate other labelled data during model training, from additional online delivery platforms such as Deliveroo or Uber Eats (although there is likely to be significant overlap in records contained), or from other countries, in order to increase the amount of data available for training and prediction of less common cuisine types.

In 2020, the impact of the latest and greatest Chinese virus, SARS-CoV-2 (coronavirus-19), has caused significant market disruptions and hardships worldwide, and its full effect on oil prices over the next year or two is likely to be significant.

reported the detection of respiratory viruses in asymptomatic individuals was as low as 4.3% from nasopharyngeal swabs suggesting that positive results in symptomatic individuals are likely to be significant [ 94 ].

( 2009 ) found that the replacement of hemlock overstory with hardwood species in the Great Smoky Mountains National Park will have a negligible effect on long-term stream conditions, but impacts from the transition period from hemlock to hardwoods are likely to be significant.

The parameters that tended to vary the most were the autoregressive effects, although this may be due to the general tendency for autoregressive effects to be stronger and, thus, more likely to be significant than cross-lagged effects.

The impact on industry partners is also likely to be significant, not just those supporting clinical trials, but those with whom institutions have master research agreements that support research, equipment purchases and many other related activities.

tobacco) as there are likely to be significant differences in the chemical contents (particularly acrylamide precursors) of the two different matrices.

In countries with a high incidence of infection like India there are likely to be significant number of window period donations that can be identified by NAT as in our study.

However, there is likely to be significant policy interest.

In this regard microorganisms within clouds and particulate dust plumes are likely to be significant.

The economic cost of reagents and deploying these machines to sub-Saharan Africa and Southeast Asia for use in malaria surveillance is likely to be significant and will necessarily need substantial bioinformatics expertise and special training for sequencing data analysis with existing software (e.g., HaplotypR, SeekDeep, and PASEC) ( 17 , 20 , 23 ), reagent supply, and equipment maintenance.

Results were less likely to be significant when the outcome was a continuous variable (e.g., number of hours of missed work) compared to a dichotomized variable (yes/no).