“likely to be significant”

In Figs 1H , 2A – 2C , 5 , S2 , S3 , S16A , and S19 , Bayesian statistics was applied to test the difference in mean synaptic efficacy and synaptic CV between two groups that follow normal distributions because the frequentist statistical tests with a large number of simulated results are likely to be significant.

These differences are likely to be significant since pilA has been linked to virulence of type B strains and is missing in the attenuated vaccine strain LVS.

Since all of these constructs show innate Xrn1 resistance, upstream and downstream sequences in the genomic RNA from which they originate, are less likely to be significant.

(1) coding regions-variants in coding regions are more likely to be significant.

A relatively low antibody prevalence (∼ 10%) in serological survey of these animals suggested them less likely to be significant reservoirs of RRV, BFV and JEV. 3.1.4 Bats Bats have been associated with several zoonotic pathogens including viruses causing Ebola (filo virus), Lassa fever (Lassa virus) and COVID-19 (SARS-CoV-2).

Although the prevalence and pattern of ADEs vary depending on the patient population, settings, ADE definitions, and methods [4] , the burden of ADEs is also likely to be significant in other geographical areas.

We therefore could not assess the degree to which COPD is underdiagnosed in the general population, although we know that this is likely to be significant. 34 , 35 The number of patients in Rotherham who have a diagnosis of COPD recorded on their primary care record can be determined from the Quality and Outcomes Framework (QOF) dataset.

Additionally, it is also important to consider that HRI is a multifactorial condition and that other factors, such as body condition score and age, are also likely to be significant factors in the development of HRI in addition to skull morphology.

Additionally, our findings confirm that adolescent-reported parent–child relationships are more likely to be significant family social resources, substantially facilitating learning engagement. 4.3 Implications The present study investigated the association between parent–child discrepancies in educational expectations and study engagement among adolescents from both the parents’ and adolescents’ perspectives.

These characteristics are likely to be significant in disfavoring recombination events between distinct chromosomes, but this remains to be experimentally tested.

Therefore the role of HSP72, 73 and 90 is likely to be significant in chondrosarcoma.

It is not clear to what extent these public attitudes have been shaped by veterinary advice; however, its influence is likely to be significant.

We observed other statistically significant associations between lifestyle variables and gene methylation that were significant for only one or two methylation cut points, making these associations more likely to be significant due to chance rather than genuine findings.

As S substantially reduces the solubility of Cl in silicate melts under oxidizing conditions 17 , and given the comparatively high oxygen fugacity and S contents of MSV magmas, the S effect in these magmas is likely to be significant.

A family-wise error (FWE) correction based on Gaussian random field (GRF) theory was applied to control for false positives resulting from multiple comparisons at the α = 0.05 level ( 56 ) and cluster-based inferences about findings for which there were likely to be significant activation effects ( 45 , 57 ).

As a result of this analysis, we concluded that changes in abundance are likely to be significant if they are greater than 6-fold.

Irrespective of this, it would seem conservative to state this relationship since that relationship is likely to be significant in a larger study (only n=15 patients with delirium means very limited statistical power). 9) Limitations of the study have been listed in the last paragraph of the discussion.

Practical considerations and recommendations for prostate cancer tumour molecular diagnostic testing Increased understanding of the link between molecular diagnostics and access to novel targeted therapies are likely to be significant motivating factors in implementing changes in the practice of tumour sample collection and processing.

Experimental and modelling evidence suggests that ecosystem recovery after pulse disturbances is likely to be significant but incomplete, and highly dependent on the type of impact and ecosystem 84 , 85 .

Besides identifying the pathogenic variant in the 11 albinism patients, the panel sequencing also made it possible to analyze the common variants of the entire cohort: a recent study suggested that TYR variants S192Y and R402Q are likely to be significant modifiers of other pigmentation gene variants.

The indirect costs are unknown but are likely to be significant, given the high prevalence of DSH in the community. 15 Guidelines for management of self-harm suggest that treatment should be tailored to individual need. 15 Associated conditions such as depression and anxiety disorders should be treated with psychological, pharmacological, and psychosocial interventions. 15 Psychological interventions that are specifically structured to reduce self-harm are recommended, but there is less evidence to support the use of drug treatment. 15 At the same time, psychiatric care of young people following DSH is hampered by low compliance.

In the subsequent analyses, we found that the predictive efficacy and stability of the model were good, which also suggested that emotional and sleep factors are likely to be significant factors independent of the condition, consistent with previous studies [ 10 , 27 , 28 ] but this requires further investigation.

Conversely, residues like C, L, and A exhibit lower scores across all serotypes, implying they are less likely to be significant epitopes.

Abstract The impacts of the COVID-19 pandemic on food and nutrition insecurity are likely to be significant for Small Island Developing States due to their high dependence on foreign tourism, reliance on imported foods and underdeveloped local food production systems.

By the age of 24 months, the cumulative risk of HIV infection among infants who received short antiretroviral prophylactic regimens and were uninfected at 1.5 months was 9.7% [ 17 ] This suggests that even with the proper application of sd-NVP there was likely to be significant continued vertical HIV transmission throughout the breast feeding period among our study population (unless the mother was taking HAART).