While it is unlikely that this filtering could remove all of the false positives from this large source of error, the improvement is likely to be significant.
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There are likely to be significant challenges for FDA reviewers.
argued the importance of examining social-psychological processes, which are likely to be significant in the context of ED psychopathology [ 41 ].
, annotations assigned to genes that are strongly co-expressed are more likely to be significant ( Goeman and Buhlmann 2007 ; Gatti et al. 2010 ; Tamayo et al. 2016 )].
There are also likely to be significant temporal and generational variations in fitness which may have profound effects on vector-virus interactions and subsequent outcomes of infections.
More broadly, none of the existing models account for the temperature dependence of the coupling contribution, the role of surface chemistry in modifying the accommodation coefficient at the gas–solid interface, which is likely to be significant in real-world operating conditions.
Considering a statistical power of 80%, a correlation of 0.122 is likely to be significant with a sample size of 525 (female subsample size) and a correlation of 0.265 is likely to be significant with a sample size of 109 (male subsample size).
8 It may therefore be preferable to use nylon sutures in cases in which eye rubbing is likely to be significant and where multiple sutures are required to close corneal wounds.
The nature and configuration of the social and built environments therefore are likely to be significant covariates of infection risk, and consequently, the resulting geographical distribution of incidence.
In real applications to complex bio-molecular data, we suggest to apply both Bernstein -based and χ 2 -based procedures: structures discovered by both tests are likely to be significant, and Bernstein -based tests can discover potential structures not detectable with the more selective χ 2 -based test.
11) There are likely to be significant modifications of other residues such as disulfides, Trp and Tyr residues on the modified proteins.
While all analyses focused on direct medical costs, there are likely to be significant societal costs associated with treatment of DCIS.
Inter-annual RSL variability is also likely to be significant, into decimetres in places, in the near future (e.g., Palmer et al., 2020 ) and it may take decades for the signal of anthropogenically forced RSL change to be clearly detectable (Lyu et al., 2014 ) and influence shorelines (D’Anna et al., 2022 ).
The viability of this cell line was slightly lower after ablation of eEF1B than the other cell lines, but not to an extent that seems likely to be significant.
The current literature makes it possible to identify metabolic pathway disorders that are likely to be significant in the development of PE, including insulin resistance, disorders of energy metabolism, oxidation processes, lipid metabolism, and activation of inflammatory processes [ 11 , 13 ].
Mechanisms related to other QTLs for growth-response occurring at germination (in tomato [ 90 , 91 ], rice [ 92 ], barley [ 93 ] and wheat [ 89 ]) or during reproductive development (rice [ 94 ], barley [ 95 ] and tomato [ 96 ]) are likely to be significant for field pea and warrant further investigation.
Randomized controlled trials, with much larger patient numbers, are likely to be significant to establishing precision medicine protocols as a standard of care for prevention and treatment of cognitive decline.
Given the differing levels of resources and inequality in incomes which persist in the South African context ( May, 2000 ) and the transitory nature of SES within this setting ( May and Woolard, 2007 ), the possible ways in which SES may alter these relationships is likely to be significant.
7 , 8 The mechanisms that may be involved in Ps and AD itch are complex and multifactorial, 9 however, the role of inflammation is likely to be significant since several inflammatory mediators elevated in both conditions are known to cause itch and anti-inflammatory treatments can reduce inflammatory signs as well as itch. 8 , 10 Interleukins are cytokines which play key roles in pro-inflammatory and anti-inflammatory signaling pathways.
Most often, they are based on the results of atmospheric samples (metrology) taking into account only the respiratory route and excluding risks related to skin contact and ingestion, which are likely to be significant.
Any synthetic effects involving the ARK1 or the PRK1 genes are likely to be significant since ark1 Δ and prk1 Δ single-mutant cells are very similar to wild-type cells in terms of appearance and growth.
This is captured in Step 1a: Are there likely to be significant negative human or environmental impacts to farming the novel species?
Costs are likely to be significant once extrapolated to the wider NHS level.
As linear regression is considered robust to violations of the assumptions, we next explored whether sites that violated an assumption were more likely to be significant in a DNAm analysis using a linear regression model.
Abyssal demersal fish are typically large, mobile scavengers and predators, and are likely to be significant in the maintenance of ecosystem structure and function.