“likely to be significant”

DNA thietanes are therefore likely to be significant contributors to the particular S 4 dT/UVA sensitivity of NER-deficient XPA cells [24] , [62] .

It is a key step in RA, helping determine if the potential harm from a substance is likely to be significant.

The χ 2 value is more likely to be significant when the sample size is large for assessing the model’s goodness of fit [ 45 ].

As features at a very fine scale are less likely to be significant, we ignore features with a very low scale (a scale-space value of 1.1 was empirically selected as a good cut-off) and weight the contribution (see w n above) of matching keypoint pairs based on their absolute and relative scales: where f i ∈ F i and f j ∈ F j are the candidate features in images I and J , is their mean scale, and a value of P = 0.10 yielded best results on an evaluation set.

The two large clusters found in our cortical thickness analysis are more likely to be significant, and true positive.

These differences are likely to be significant for metabolites with low concentrations, but irrelevant for metabolites with high concentrations, depending on the relative impact upon the difference from the corresponding concentration value.

For example, there are likely to be significant opportunities from the use of advancing remote sensing technologies on mangrove extent and subsequent carbon stock estimates will be key to ensure that estimates remain consistent in the long-term, and through the integration of various modelling processes.

However, based on the known effects of reactive oxygen species, ATP, and other purinergic effectors on the microbiome [ 24 ], vagus nerve [ 152 ], adrenal function [ 153 ], and even hypothalamic function [ 154 ] via circumventricular organs that lack a blood brain barrier [ 155 ], these synergistic multi-system effects are likely to be significant.

67 The effects of spatial heterogeneity in ion channel expression and in fibre organisation on the arrhythmogenic effects of EAD susceptibility induced by drug block are likely to be significant in the translation from single-cell EADs to tissue- and organ-level effects.

Accordingly, there is likely to be significant variation in the prescribing practices of anticoagulants nationally between different areas.

Indigenous peoples therefore hold a different worldview where the concept of self is collectivist and inseparable from land, family, and community, and this view is likely to be significant in their concept of aging well.

62 63 Also, we acknowledge that there may be substantial variation in opioid dose changes attempted by participants over the 12-week study period, and there is likely to be significant variation in participants’ satisfaction, engagement with and adherence to the ‘usual care’.

Therefore, the impact of such an assessment is likely to be significant.

Conclusions Shared familial factors, including genetics, are likely to be significant contributors to the response of several markers of body composition and cardiorespiratory fitness following PA.

The limited lifespan of these patients also influenced this as parameters related to limited skin perfusion and existing PU are likely to be significant only with longer duration of follow-up.

The clinical significance of this 2.6‐mm Hg reduction on a population level is likely to be significant.

Whilst we have named antidepressant groups based on trajectory at a population level there is likely to be significant heterogeneity in individual circumstances, whereby individuals are not experiencing the group level dynamic, e.g. co-morbidities and interactions with anxiolytic and anti-psychotic treatments might be driving antidepressant trend rather than the disease worsening.

The influence and cumulative effect of the many images of alcohol through reality TV and other forms of media are likely to be significant underlying influences on their perceptions of normal and acceptable drinking behaviours.

As the tumours in our study all regressed on chemotherapy, these studies all suggest that there are likely to be significant errors in the clinical measurements that will not lessen as the tumours shrink.

The impacts of lockdown measures on sun exposure levels are largely undescribed, although depending on their severity are likely to be significant.

Although the mental health of children does appear to be suffering due to the pandemic and the long-term sequelae are likely to be significant, family routines represent one resilience-promoting factor with the potential to mitigate these adverse influences.

19 Unfortunately, the mechanism of GC therapy slowing cardiac disease remains unclear and is likely complex; in addition, GC type and dosing regimen are likely to be significant confounding variables.

Automating patient-preferred virtual rehabilitation will undoubtedly yield health savings, which are likely to be significant given the burden of economic costs associated with these conditions.

Furthermore, the fact that the women in the sample have 2 children on average, followed by mothers with 1 child, is likely to be significant, making it easier to organise work-family activities than those in households with more children.

The impact of increased screening interval, particularly in high-risk women, is likely to be significant, and we hope further to evaluate this indirect effect of the COVID-19 pandemic.