“likely to be significant”

The cost implication is likely to be significant in light of the strain imposed on intensive-care and high-care wards.

Detrimental effects are most likely to be significant in children and adolescents, who are more vulnerable to certain infectious diseases and adverse experiences due to their immature physical, immunological, and mental development.

However, the chi-square statistic is sensitive to sample size, such that chi-square tests with larger samples are more likely to be significant (Schermelleh-Engel et al., 2003 ).

SNPs in 5'-untranslated region showed the largest difference and were 9.2 times more likely to be significant eQTLs.

Thus, there is likely to be significant bias in background factors in the comparison of outcomes between treatments.

However, these bald numbers are likely to be significant underestimates.

Intra- and inter-tumour heterogeneity in mutation burden are also likely to be significant determinants of treatment response, and are not routinely considered in current binary ‘wild-type/mutant’ tumour classifications.

However, this hypothesis is less likely to be significant, considering that the age of the female participants at baseline is mostly beyond the perimenopausal period.

Student pastoral and financial issues (likely to be significant for indigenous students given their socioeconomic and demographic profile), 40 psychological characteristics, 41 student learning styles 37 and relevant medical curricula or structural factors 39 may also play a role.

However, a significant proportion of this difference in health burden remains unexplained, such as in cardio-vascular disease, diabetes, obesity and many cancers where environmental factors are likely to be significant [ 13 - 19 ].

A 7-point change in severity score is likely to be clinically significant because this magnitude of change (1) is consistent with the resolution of 1 “very bothersome” symptom plus a 1-point change in severity of 2 symptoms and likely to be significant to patients (where “very bothersome” symptom equals 5 points), and (2) is approximately 1 SE of the mean based on our pilot data (SD 30, n = 18) and consistent with distribution-based methods.

On the other hand, the terms that fall between the Bonferroni limit and the t -value limit are considered likely to be significant, while the coefficients below the t -value limit are insignificant [ 24 ].

Various authors have also identified the importance of contextual issues that are likely to be significant for clinical and health networks, including the particular health issue, the disciplines and specialisms involved ( 39 , 41 ) and the local context of participants ( 42 , 43 ).

However, there is likely to be significant sub-national variation.

Additionally, we were unable to incorporate dynamic laboratory trends, microbiological data such as the history of multi-drug-resistant organism (MDRO) colonization, or social determinants of health, all of which are likely to be significant predictors, particularly in contexts with limited resources.

population compromised by MetS, the health impact of oxidant and particulate air pollutants in this sensitive population is likely to be significant.

Table 2 shows a list of disorders associated with primary or secondary myelofibrosis; Table 3 shows conditions where the fibrosis is likely to be significant and, in some cases, may be associated with deposition of collagen) [ 8 , 9 ].

The WA Police Force recruit injury database also had some missing demographic data (10.2%) and some injuries that were not accurately described which were subsequently assigned as ‘unspecified.’ This may have influenced the results, however given these data should be missing at random we do not think the influence is likely to be significant.

This may show how an emphasis on literacy skills at the school level during certain ages may positively influence within-subjects data or make between-groups comparisons less likely to be significant when studying literacy during this developmental stage.

These differences were broadly and bilaterally distributed over frontal, temporal, and parietal regions, and were more likely to be significant over the right hemisphere.

In mismatched years without precise estimates of the distribution of type B lineages, the available descriptions suggest that all of the mismatches were likely to be significant or complete. 4 DISCUSSION The evidence we reviewed from the published literature indicates that influenza is an important cause of morbidity in the Asia‐Pacific region and affects all age groups.

There is likely to be significant variation in passenger experience of individual airlines depending on other personal health‐related factors, such as grade of obesity, presence of medical comorbidities such as osteoarthritis and obstructive sleep apnea in passengers with higher grades of obesity, and passenger mobility.

Comorbidity with epilepsy and cerebral palsy are likely to be significant modifiers of the relationship between intellectual disability and respiratory mortality.

It is therefore imperative to consider unintentional weight loss, patients' levels of physical activity and diet composition in ageing populations, as these factors are likely to be significant contributors to the onset of risk factors and frailty [ 31 ].

Thus, does TXA 2 signaling condition the metastatic niche to create a more nurturing environment? The effects of TP on cancer-associated fibroblasts have not been investigated; however, they are likely to be significant given the emerging role of these cells and TXA 2 signaling in tumor progression.