“just failed to reach statistical significance”

In the full sample, the intervention was associated with a statistically significant improvement of insomnia symptoms at postintervention that was maintained at follow-up, although the latter just failed to reach statistical significance.

One was a well-conducted study that also showed a positive effect on caregiver strain, a trend that just failed to reach statistical significance.

In the whole cohort, the greatest loss of GFR was seen in patients with DSR at time point 2 ( Figure 2 a) and approximately 65% of patients with DSR at this time point appeared in the “deteriorating subgroup”; these relationships just failed to reach statistical significance.

Discussion Our results show that providing practices with access to an ICCD service led to an increase in the proportion of patients achieving targets for control as assessed by our primary outcome measure (control of HbA1c, BP and cholesterol), although this just failed to reach statistical significance.

For individuals with A1012G heterozygous status, a significantly lower odds ratio (OR: 0.046, 95% CI: 0.004–0.51, p=0.012) was observed for adolescent disease onset and sex (OR: 0.23, 95% CI: 0.047–1.14, p=0.07); a trend for females to have a higher likelihood of possessing the polymorphism being observed, although this association just failed to reach statistical significance.

The fairly small sample population may be the explanation for why this association just failed to reach statistical significance.

Isolation-induced down-regulation of Klf2 just failed to reach statistical significance during our qRT-PCR validation of RNA-Seq data, but Krüppel-like factor 2 (KLF2) activators have anti-inflammatory effects in vascular cells ( Xu et al., 2017 ; Lei et al., 2022 ) and any demonstration of similar properties in brain tissue would still be of potential interest.

The repeated-measures ANOVA revealed a significant effect for amplitude F (2,32) = 17.44, p < 0.001 and an effect for condition F (3,48) = 2.79, p = 0.050 that just failed to reach statistical significance.

The differences in analgesic effect just failed to reach statistical significance at T 30min , T 4 , T 8 , and T 12 .

There continued to be a difference in Scond between the heart failure nonsmokers and controls when the smokers were removed from the analysis, while LCI just failed to reach statistical significance most likely due to a loss of statistical power (see Figs. 1 – 3 ).

One of the most interesting and potentially clinically relevant finding from our study was that lower set‐shifting ability (percentage of perseverative errors) at baseline tended to be associated with a lower reduction in eating disorder pathology (EDE global score) until the 18‐month follow‐up, although this finding just failed to reach statistical significance, which may have been the case due to the low sample size.

For the moment, however, particularly since the association just failed to reach statistical significance and is inconsistent across the three cohorts, this observation remains of interest but requires replication in other populations.

Third, the task-dependent acceleration of the median latency of fixating heads at the very first fixation after scene onset just failed to reach statistical significance on a very conservatively corrected level in some post hoc analyses (i.e. the analysis of shift functions and the analysis for distinguishing task from practice effects in the electronic supplementary material, section S1 and table S1).

Moreover, a considerably higher proportion of GSD participants (77%) than PSD participants (60.7%) reported being recovered or improved on gambling symptom severity at the 24 month evaluation, a difference that only just failed to reach statistical significance.

Similarly, WMC was greater for the Strategy group than the Puzzle group but this just failed to reach statistical significance with a two-tailed test.

This approach was chosen in accordance to Hosmer and Lemeshow [ 94 ] who recommended to also consider variables that just failed to reach statistical significance in the univariate models as candidate for the multiple regression model to avoid loss of information.

4-FA also reduced spatial memory performance as compared to placebo, but this difference just failed to reach statistical significance.

The adjusted prevalence OR of bacterial vaginitis symptoms was just failed to reach statistical significance (95% CI = [0.998–2.084]), and the adjusted incidence OR was significant.

Quantification of the 6E10-positive deposits showed a slight increase in AM; Serf2 br −/− compared with AM, but this just failed to reach statistical significance in the Bonferroni corrected post-hoc comparison (two-way ANOVA: all 3m non-AM versus AM groups p bon < 0.0001; AM versus AM; Serf2 br −/− p bon = 0.063) ( Fig 5F , left panel).

Similar to the histological results, biochemical analysis appeared to demonstrate an association between histological microcalcification content and elastin concentration (Spearman ρ=0.38; P =0.052) although this just failed to reach statistical significance.

Results were similar when expanding the definition of dementia to first clinical or administrative code recorded in primary care records (N=39 028; HR 0.85, 95% CI: 0.72 to 1.01), although they just failed to reach statistical significance.

Additionally, a recently published analysis of this study group stratified by the modified version of the Charlson Comorbidity Index (mCCI) shows a similar trend towards a worse outcome of patients with high mCCI under medical rhythm control, which just failed to reach statistical significance due to being underpowered [ 24 ].

Similar to the addition of molasses, the addition of cassava meal to Napier grass resulted in increased lactic acid contents compared with the untreated silage but the difference just failed to reach statistical significance when cassava meal instead of molasses was used.

The reduction in total colorectal polyp number associated with EPA use in the seAFOod trial was modest and just failed to reach statistical significance ( 17–18 ).

50 In a third study with a different probiotic treatment, an improvement was observed in the composite score of IBS symptoms in the probiotic group vs the placebo group, but this just failed to reach statistical significance.