“highly significant”

The enrichment was highly significant and robust, and dependent on both the 33 genic and 38 intergenic insertion sites of the three species (1e-05< P <0.0006; Table 1 and Supplementary Data 3 ).

The first primary outcome variable tested, the difference between groups in TBUT, was in fact, highly significant (p=0.0006), and it is worth noting that the difference between groups for the second primary outcome, OSDI, did not approach statistical significance (p=0.9843).

The difference of resistance against starvation-induced cell death was highly significant with pIGFBP7 transfected Jurkat cells showing 85 % more proliferation measured by WST-1 signal on day four compared to the pCntrl cells ( P -value = 0.0006; Fig. 2b ).

In this context, among the associated modules, the dark grey module exhibited a moderate positive correlation with M-B- (r = 0.49, p = 0.05) and a strong, highly significant negative correlation with M+B+ (r = -0.76, p = 6×10 -4 ) ( Figure 5A ), reflecting a coherent and biologically meaningful inverse association with the transmission status.

This effect is statistically highly significant (γ = 95%, p = 0.0006).

The pooled estimate remained highly significant (RR = 0.45 [0.29–0.71], p = 0.0006, I 2 = 0%).

Our study was not designed to detect the correlation between HPDT and areas of secondary hyperalgesia; however, we find a highly significant result (P = 0.0006).

FHO/RP ratio did not present significant differences in yellow-green light conditions in between groups comparison, whereas in infrared light condition the comparison between groups showed a highly significant difference (p = 0.0006) with a larger ratio in Control Group (1.055) compared to TMD Group (0.967) ( Table 2 ).

The between-group comparison confirmed a highly significant difference ( p = 0.0006), suggesting a notable effect of CKDB-322 on leptin regulation.

While variation in hK7 expression levels was highly significant in male patients suffering from asthma either since birth (p = 0.0006) or for the last 1-10 years.

unrelated) were also highly significant ( p < 0.0006).

However, the interaction with radiotherapy was highly significant ( p = 0.0006).

2 g) revealed a highly significant increase in contact area between the rhBMP-2 (90.72% ± 4.12%) and the sEV-treated group (59.30% ± 12.46%; p = 0.0006).

Effect of treatment, landscape diversity, and prairie vegetation on the bee community Regression analyses with the presence or absence of prairie strips and Shannon landscape diversity as independent variables indicated that strip treatment had a highly significant effect on the abundance of all bees ( Fig 3a and S6 Table ; p = 0.0006), 8 common bees ( Fig 3b ; p = 0.0014), 9 common bees ( Fig 3c ; p = 0.0022), and uncommon bees ( Fig 3d ; p = 0.0002).

The differences in FLA value between alleles OsFLA6 AA and OsFLA6 GG were highly significant (Welch's t -test; P = 6.06E−04) ( Figure 3E ).

In addition, when Subtype 2 was compared with all other subtypes combined, a highly significant survival difference is still observed (log-rank test, P = 0.00061).

The difference between experimental conditions was highly significant (W = 88, p = 0.00061).

As shown in Table 6 , for CVMI, the p-values were highly significant in females ( p = 0.00061) and males ( p = 0.00371).

First, in our NSG study the difference between MmuPV1+DMBA and mock+DMBA groups was highly significant ( P = 0.00061), and no NSG mice treated with DMBA alone developed HSIL or cancer by the study endpoint.

Considering the polymorphic variants of SCN5A, rs1805124 (H558G), the G558 allele had similar frequencies in all studies (24.4%, 18.4% and 23.4%, respectively), with a highly significant association with the PR interval value ( p = 6.2 × 10 4 , heterogeneity of p = 0.09).

Plasma leptin levels follow the same pattern as body fat percent (AB interaction F 1,56 = 11.32, p = 1.39 × 10 -3 ), and fasting C-peptide levels also show a highly significant AB interaction term (AB interaction F 1,56 = 13.13, p = 6.29 × 10 -4 ) and a similar profile of dysregulation.

Even in the more challenging GSE59455 cohort, ICDRS still provided significant risk stratification ( P = 0.0089), and in GSE65904 the survival difference between high- and low-risk patients remained highly significant ( P = 0.00064).

The statistical comparability of the two clones revealed highly significant variations at all time points (day 1: p = 0.00064; day 2: p = 1.87E-06; day 3: 2.82E-17; day 6: 6.23E-06; n = 12) ( Fig. 1C ).

Additionally, Body Mass Index (BMI) categories demonstrated a highly significant association with readmission status (x 2 = 21.513, p = 6.4778 × 10 −4 ), characterized by a non-linear relationship where underweight patients exhibited the highest readmission rate (15.79%) and obese patients the lowest (11.49%). 4.2.

Using this approach, we found that a highly significant overrepresented upregulated pathway (p = 6.50E-04) was the Hsf1 ( heat shock factor 1 )-dependent transactivation pathway, with the following twenty upregulated transcripts supporting this pathway enrichment, including: Akt1s1 , Rptor , Tnfrsf21 , Serpinh1 , Hspa1b , Hspa1a , Col4a6 , Fkbp4 , Cryab , Mtor , Camk2b , Hsf1 , Ubb , Mlst8 , Hspb8 , Hspb1 , Hspb2 , Slc29a1 , Hspa2 , Dedd2 .