“highly significant”

The difference between values for the TEVGs and PTFE grafts was highly significant ( p < 0.0001).

Furthermore, Tukey’s post hoc test confirmed a highly significant difference ( p < 0.0001) between these groups.

The measured 2.4–2.6% CO 2 concentration translates into a highly significant increase in CO 2 with a KN95 respirator and a valved respirator at the nasolabial fold (p < 0.0001), which is much greater than the NIOSH 8h threshold limit value [ 57 ].

TNFR1 expression significantly increased in all HIFU-treated Hep3B cells at both 24 and 72 h ( p < 0.0001) as compared to control, and there was also a highly significant difference in the expression between standalone HIFU and ethanol + HIFU treatment groups ( p < 0.0001).

Thoracolumbar muscle hypotrophy also showed a highly significant time effect [ F (1.922, 34.60) = 22.33, p < 0.0001], although post-hoc comparisons did not identify specific time points that differed significantly from baseline in either group ( Figure 10 ).

Thus, during the transition from pole to brain control in task 1, the average correlated firing between pairs of cortical neurons, measured in terms of correlation coefficient (mean ± SEM), increased from 0.02 ± 1 × 10 −4 to 0.06 ± 2 × 10 −4 , a 3-fold rise that was highly significant (Wilcoxon signed rank test, p < 0.0001).

The level of SC5b-9 increased significantly at T2 in the normothermic group, and the differences between T1 and T2 and between T1 and T3 were both highly significant (P<0.0001, Fig 2B ).

Parameter estimate for t-1 was 0.74, and this relationship was highly significant (p < 0.0001).

coluzzii populations An overall highly significant elevated levels of AChE (F 2, 237 = 55.93, P < 0.0001) and β-esterase (F 2, 237 = 159.0, P < 0.0001) activities were observed in both indoor and outdoor mosquito populations compared to the susceptible reference strain, Kisumu (Figs. 3 a–d).

The ANOVA outcomes inferred a highly significant difference (P < 0.0001) among rice accessions for grain size/weight trait variation despite significant environmental (years and geographical locations) and block replication effects on these traits ( Table S3 ).

All three factors had highly significant effects ( p < 0.0001), and signal intensity levels were compared between the species using Student’s t -test on residuals after the effects of Dye and Subarray had been removed.

We found that the associated SNPs rs950169 and rs2135551 showed a highly significant correlation with the use of an alternative splice acceptor site, resulting in a truncated PLAC (protease and lacunin) domain in the ADAMTSL3 protein (p<0.0001, Figure S2 ).

Highly significant interactions were observed between a MDD status and alcohol frequency (all p values ≤ 0.0001).

The latter was highly significant compared to the values of the WT littermates (mixed effects analysis, genotype p < 0.0001, age p < 0.0001, interaction p < 0.0001; Sidak’s post-hoc test 12 m, p = 0.0001).

All tests yielded highly significant results, with p -values < 0.0001, providing strong confidence in our findings (Supplementary Table 4).

Following gentamicin intervention, Caspase-3 fluorescence signals significantly increased, with mean fluorescence intensity showing a highly significant difference compared to the control group ( p < 0.0001), demonstrating that gentamicin effectively induces vestibular hair cell apoptosis.

In particular the difference in terms of the exosome number between PCa patients and CTR was highly significant (p<0.0001).

A highly significant correlation between lactose and fructose malabsorption could also be noted (6.8% LI vs. 0.2% non-LI; P<0.0001; OR 31.06) ( Table 2 ).

However, the performance gap between the leading model (DeepSeek) and the baseline model (ChatGPT-3.5 Turbo) was highly significant ( p < 0.0001), confirming substantial advancements in newer models.

This was supported by highly significant group × trial interactions (path lengths: F 160,3360 = 1.69, p < 0.0001; search preference: F 40,840 = 2.28, p < 0.0001).

All group comparisons were highly significant ( p <0.0001).

In addition, a highly significant association ( p <0.0001) was observed between weight gain and the number of cigarette-free days.

Overall, these highly significant (p < 0.0001) associations between epithelial and stromal marker proteins KRT19, CDH1, VCAN, and FAP with LMD-enriched tumor epithelium and stroma, respectively, were observed using the proteomic data from the additional 9 HGSOC cases assessed ( Figure 3 B).

Results: Baseline pre-injection mean PRTEE score was 72.8 ± 6.97 which decreased to a mean PRTEE score of 40.93 ± 5.94 after 2 weeks of injection which was highly significant ( P < 0.0001).

Concerning SIRT1 SNP rs3758391, a highly significant statistical difference was observed in the T allele frequency and TT genotype distribution between the normal control and breast cancer groups (p < 0.0001).