“highly significant”

The interaction between plasma treatment and salinity was highly significant ( P < 0.0001) across all GP parameters, highlighting the complex relationship between these two factors.

Interestingly, we recently showed that IL2 stimulation in vitro also leads to a highly significant ( p > 0.0001) hyperproliferation of ID lymphocytes compared to the lymphocytes of control cows [ 5 ], which also highlights the importance of this axis for the immune deviant phenotype.

3 a): A one-way ANOVA showed a highly significant between-groups difference ( F (4,55) = 10.32; p = 0.0001).

This starkly contrasted with the control group, which exhibited a much higher activity level of 152.33±12.71 U/mg protein, with a highly significant difference ( P <0.0001).

The mean change from baseline was 0.97 ± 0.40 to 0.39 across all follow-ups with a highly significant P- value of < 0.0001, indicating a sustained and statistically significant enhancement in contrast sensitivity over the 12 months [ Fig. 2 ].

A highly significant inter‐patient variation in annual progression rate was detected (variance of β r 0.893; p < 0.0001).

Kaplan–Meier analysis demonstrated a highly significant survival difference, with high-risk patients showing markedly worse overall survival than those in the low-risk group ( p < 0.0001; Supplementary Figure S4b ).

This observation was confirmed by two-way ANOVA, which crossed bivalve species with sampling month , revealing highly significant differences between summer and winter ( p -value < 0.0001).

Combined ANOVA results revealed that variations among the RILs of both populations were highly significant ( p < 0.0001 or p < 0.05) for all six traits ( Table S2a,b ).

Highly significant negative associations between DAS28 at the start of treatment and remission at 12 months were also found by logistic regression ( p < 0.0001) for both types of remission.

The non-parametric one way ANOVA of prediction scores distribution among categories was highly significant for all three metapredictors ( p < 0.0001 for all predictors with VEST3 Kruskal-Wallis statistic K = 156.1, REVEL Kruskal-Wallis statistic K = 113, ClinPred Kruskal-Wallis statistic K = 168).

There was a highly significant increase in BMS scores for drug‐treated mice versus vehicle beginning at week 1 (4.2 ± 1.2 versus 0.2 ± 0.1; p < 0.0001).

Our findings uncovered a highly significant effect of MS ( p < 0.0001).

We found a highly significant increase in synaptic abnormalities in oocytes from BPA-exposed females (16.0% versus 52.0% of cells in placebo and BPA, respectively; χ 2 = 134.8; p < 0.0001; Figure 1 A), largely attributable to increases in two categories of abnormality: “incomplete synapsis,” in which a single chromosome pair remained unsynapsed in an otherwise normal pachytene cell (0.5% in placebo versus 11.0% in BPA; Figure 1 C), and cells with end-to-end associations between nonhomologous SCs (7.7% in placebo versus 25.6% in BPA; Figure 1 D).

However, the “Day Post-Injury” is a highly significant factor (two-way ANOVA, α = 0.05, p < 0.0001), and in general demonstrates that the bluest shifted myelin (Day 21, Adult) was significantly different in PI than the most red-shifted myelin (Day 27,30). 3.1.2.

The decline in mortality was much steeper in the younger age group, and the interaction between age group and calendar year was highly significant ( p < 0.0001; Supplementary Table S21 ).

Correlation of these two cytokines regarding the whole study group (n = 48) was highly significant (p < 0.0001, Spearmans rank correlation) upon stimulation with Penicillium chrysogenum (r s = 0.82) and Aspergillus fumigatus (r s = 0.80) and after stimulation with 10 pg/mL endotoxin (r s = 0.55).

As expected, we found a highly significant trend for increased concentrations of leptin with increasing levels of overweight or obesity ( P < 0.0001).

All correlation coefficients were highly significant (p < 0.0001).

For all interactions, the global null hypothesis test was highly significant ( P ‐value < .0001).

The log-likelihood ratio tests indicated that both group and kin effects were highly significant (p < 0.0001).

This difference is statistically highly significant (P = 0,0001 Student’s t test).

We found a highly significant difference between intra- and inter-subject mean durations (Student’s t -test, t (18) = 13.926, p < 0.0001; Fig. 5 B, upper-right inset).

A total of 210/337 genes demonstrated negative correlation coefficients with all metallothioneins (F, G, H, M and X), giving a highly significant P value ( P <0.0001).

An analysis of variance, with sense of closeness as the dependent variable and all nine variables as factors, was highly significant (F 11,17 = 25.89, p < 0.0001).