“highly significant”

This PBC-associated delay in CCA growth was highly significant (P < 0.0001, mixed-effects model) compared with control and PSC mice, with some tumors that even failed to develop in several (five out of nine) cases ( Fig. 3, C and D ; and Fig.

The 6-OHDA lesioning ( n = 8) caused a near-complete and highly significant (96.8 ± 1.8%, Two-Sample t -test, p < 0.0001) abolishment of DAT at the level of the CPu ipsilateral to the lesion in experimental cohort 1.

Correlation between LCD and genetic affinity were highly significant for a period of 5950–15,950 BP (r = − 0.909, p < 0.0001).

The highly significant ( p < 0.0001) genotype × year interaction also indicated the major influence of environment on the traits ( Supplementary Table S4 ).

In contrast, longitudinal within-subject analysis revealed a highly significant upregulation in miR-146a-5p expression from T0 to T2 in both sexes ( p < 0.0001).

A highly significant correlation (r = 0.475, p <0.0001) was also found between the Ct values of the concordant positive saliva and NPS specimens.

The difference in OS between patients with the molecularly highly similar tumors A_IDH and A_IDH_HG tumors was highly significant (A_IDH_HG vs A_IDH: HR 2.43, 95% CI 1.73-3.40; P < .0001).

The difference of frequencies of hepatic SOS in 6-TG-containing elements compared to other treatment elements was highly significant ( P ≤ 0.0001).

A two-way ANOVA analysis showed that the ratio of activated carbon to AC-1 had a highly significant impact on the recovery rate of immobilized AC-1 strains over 120 days of storage ( F = 6.842, p < 0.0001), while the variance analysis results between the bacterial suspension and fermentation broth were significant ( F = 3.274, p < 0.01) ( Figure 1 ).

, 2019 ), the correlation between hangover frequency and severity was highly significant ( r = 0.710, P < 0.0001), suggesting reverse tolerance.

Preexisting hypertension, diabetes mellitus, coronary artery disease, chronic kidney disease and malignancy were all highly significant risk factors for 30-day hospital admission following initial ED discharge ( p < 0.0001).

The PADIT risk score was found to be highly significant ( P < 0.0001), with an estimated hazard ratio (HR) and corresponding 95% confidence interval (CI) of 1.28 (95% CI 1.22, 1.33) ( Table 3 ); thus, the relative risk of a major CIED infection increased by 28% for each one unit increase in PADIT risk score.

The results of the ELISA and the relative density of the ICT showed a highly significant correlation (rs:0.935; p < 0.0001).

The pairwise F ST values between populations ranged from 0.018 between Tensed and Thornton populations to 0.147 between Dayton2 and Parker Farm populations, although all F ST values were determined to be highly significant through bootstrapping ( P < 0.0001; see Supporting Information—Table S3 ).

Additionally, linear models assessing the importance of location in describing the canonical function generated from linear discriminant analysis were highly significant ( R 2 = 0.857, p < 0.0001). 3.2.

In contrast, the coefficient of skewness (γ skew ) is negative and highly significant (−0.0021, t = −4.0245, p = 0.0001).

The P for trend remained highly significant across all models ( p < 0.0001).

The Top ICH genes had highly significant and similar associations within the primary cluster that included intratumoral densities of CD45 + (r = 0.53–0.67, all p < 0.0001), CD8 + T cells (r = 0.48–0.71, all p < 0.0001, Fig. 3 B), CD20 + B cells (r = 0.47–0.56, all p < 0.0001), and CD138 + cells (0.37–0.5, all p < 0.0001, Additional file 1 : Table S1).

The overall survival difference was highly significant (p < 0.0001 for both pre- and post-operative subgroups).

This is not to suggest that the [ 38 ] outcomes are typical, although the percentage differences in amino acid digestibilities in wheat-based diets recorded in the same study were very similar to maize given the highly significant linear relationship ( r = 0.925; p < 0.0001).

Likewise, we were able to demonstrate the highly significant influence of lymph node status on patient survival, not only on disease-free but also on overall survival (log rank P < 0.0001, Cox P < 0.0001).

The Tukey post hoc test between minutes 00–15 revealed highly significant changes for all the populations ( p < 0.0001) (Figures 4A , 5 ).

There was a highly significant correlation between the coulter counter and blood gas analyzer methods of Hb measurement ( r 2 = 0.98, 95% confidence interval [CI] = 0.97–0.99; P < 0.0001).

There was a highly significant effect of time (F (5, 153) = 12.80, p < 0.0001) and treatment (F (1, 34) = 4.892, p = 0.0338), but no significant interaction (F (5, 153) = 1.584, p = 0.1677) over the 6-week period indicating that the animals learned the rules of the task, with anthocyanin-rich extract fed animals performing better than the control fed animals.

sylvestris was highly significant ( p < 0.0001: ****).