“highly significant”

Using RT–qPCR primers that distinguish wild type (WT) and KCNQ2 ∆E5 , we found a highly significant difference, with KCNQ2 ∆E5 detected exclusively in patient samples ( P < 0.0001 adjusting for age, sex and RNA integrity number (RIN); Supplementary Table 2 ), while the levels of WT KCNQ2 transcript were not different ( P = 0.9947 adjusting for age, sex and RIN; Supplementary Table 2 ) (Fig. 2f,g ).

The ANOVA revealed that the model was highly significant due to the low probability value ( p < 0.0001).

The effects of the target plant and the interaction between the experimental regime and the target plant were highly significant (Wald χ 2 = 1066.5, df = 2, p < 0.0001, Wald χ 2 = 167.0, df = 6, p < 0.0001, respectively).

Modest yet highly significant association was identified through Spearman's rank‐order correlation ( r s = 0.37, p < 0.0001; Figure 5 ).

The analysis of blood loss showed that the median (IQR) total blood loss was 575 mL (375, 875) in the NTA group compared to 450 mL (325, 675) in the TA group, a highly significant difference (p < 0.0001 Mann-Whitney test).

Overall, there was a highly significant difference ( P < .0001) in the number of platelets in equivalent volumes of the liver tissue between naive and refractory animals ( Figure 3 B).

0.41‐0.53; p < 0.001) and there was a highly significant overall association between morphological categories and molecular subgroups for each of the nine observers ( p < 0.0001).

The enrichment is highly significant when compared to the frequency of such chromatin for all 23,393 genes we assayed (P <0.0001, chi-square test).

We found an increased frequency of heterozygous genotype and minor allele of the TLR4 rs4986790 SNP in women with OC compared with healthy controls, and this result remained highly significant after Bonferroni’s correction for multiple testing ( p < 0.0001).

The SQUID is responsive, exhibiting highly significant (p < 0.0001) increases during a major QI initiative, and its internal consistency is excellent (Cronbach's alpha = 0.93).

At 35 days after MCAO, a highly significant tissue loss of the IL neocortex and striatum was present in both MCAO groups (P < 0.0001; Figure 4(c) ), however to a lesser extent for the CCA-MCAO group.

Results We find a highly significant positive correlation between Pfirrmann grades and the gene expression of MMP1 (r=0.67, p=0.0001), MMP3 (r=0.61, p=0.0002), MMP10 (r=0.6701, p=0.0001), MMP13 (r=0.48, p=0.004), ADAMTS1 (r=0.67, p=0.0001), and ADAMTS5 (r=0.53, p=0.0017).

Although, the fit for regression equation was poor for maize (R 2 = 0.14) and rice (R 2 = 0.16), and was moderate for soybean (R 2 = 0.35), these regressions were highly significant ( P < 0.0001) and indicate that the predictor variables still provide information about the response even though data points fall further from the regression line.

The mean age at death for animals unaffected was 614 days (SEM ± 20) compared to 741 days (SEM ± 18) for animals with pathology; a difference which is highly significant ( p < 0.0001, two-tailed unpaired t test).

Statistical analyses revealed that this elevation was small (14.5 μg/g) but highly significant ( p -value < 0.0001).

In this comparison, the difference found between the four haploidized strains and the haploid-at-all-times and diploid-at-all-times strains remains highly significant ( t -tests; p < 0.0001).

Moreover, vaccine product and DMT class were highly significant predictors of antibody responses ( p ≤ 0.0001) for both assays and age was a significant predictor on Elecsys ( p = 0.0003) and MBI ( p = 0.026) assays.

Results We observed a highly significant correlation between the storage time of pRBC units and a drop in pH, as well as an increase in potassium and lactate of stored red cells ( p < 0.0001).

The data presented in Figures 1(a) and 1(b) demonstrates that there was a highly significant increase in the expression of miR-181a-5p (4.56 ± 0.92-fold change, p < 0.0001) and miR-125b-2-3p (6.39 ± 0.68-fold change, p < 0.0001) in maternal peripheral blood of the RH-HDFN group compared with the control group.

At the Lönnstorp site, genotypic variance was highly significant ( p < 0.0001) for all traits except NS and SL ( Supplementary Table S2 ).

All p -values were highly significant ( p < 0.0001).

For adult life "body weight change" a heritability of 0.15 (highly significant, p < 0.0001) was estimated.

This showed that Ca 2+ -dependent trafficking was highly significant (Mann-Whitney test: p<0.0001; Figure 3C ).

A secondary analysis for risk score categories expressed a highly significant detrimental effect on OS and RFS for higher RS ( P < 0.0001) as in Fig. 2 .

Whereas the original data analysis reported a highly significant effect ( P < 0.0001), generalized mixed-effects models with a random effect for name indicates that the effect is not robust, neither with the data from the general public (b = −0.108 [log odd units], z = −1.712, P = 0.087) nor with the data from elected officials (b = −0.065, z = −1.432, P = 0.155). * While this does not mean that we should accept the null hypothesis, it shows that the study is underpowered.