“highly significant”

Clinical Pharmacology disease management patient‐generated online data Pharmacometrics Psychopharmacology For major depression, the same relationship was even more pronounced, with an average loss of 0.4 rating points out of 10 per decade since the FDA approval (corresponding to a Pearson's R of between −0.56), highly significant for all drugs with at least five reviews ( P ≤ 0.0001), at least 10 reviews ( P ≤ 0.0001), or at least 20 reviews ( P = 0.0002) (Table 2 ).

One-way ANOVA revealed a highly significant effect of the nanohybrid loading on TPC (F(3,8) = 784.5, p < 0.0001).

Notably, Rad-scores derived from wavelet, LoG, and combined feature classes all demonstrated highly significant p ( p < 0.0001), indicating a stronger association between Rad-scores and OS in GBM patients.

3B1 and 3B2 indicated highly significant effects of gabazine ( p < 0.0001) and behavior ( p = 0.0002), and further indicated a significant interaction ( p = 0.0314).

This was highly significant (Fishers exact test, P = 0.0001) (Table I).

A highly significant positive correlation was observed between IL-15 and IL-22 (r = 0.606, p ≤ 0.0001).

The prevalence of LBP was highly significant (p < .0001) among girls (confidence interval [CI]: 1.5 to 3.2; OR: 2.2), those who felt their school satchel was heavy (CI: 1.7 to 3.5; OR: 2.4) and those who watched television (TV; CI: 0.03 to 0.28; OR: 0.09).

total and stage I+II ovarian cancer is highly significant (P<0.0001) but negligible for healthy vs. stages III+IV cancer (P = 0.043); in contrast for the more important differentiation between benign vs. ovarian cancer, the difference between CA125 and the panel is missing for benign vs. total and stage I+II ovarian cancer and rather better for benign vs. stage III+IV ovarian cancer (P = 0.045).

( 11 ) and the analysis of variance in Table 4 , the model shows a highly significant fit with P < 0.0001, the lack-of-fit is not significant (P = 0.8173 > 0.05), indicating no lack-of-fit exists.

Statistical analysis (one-way ANOVA) confirmed that the differences in healing rates between the larva-treated groups and the infected control were highly significant (F = 31.842, p < 0.0001) ( Fig. 4 ). 3.3 Microbiological analysis Bacterial load, measured as CFU/swab of P. aeruginosa , decreased significantly in all treatment groups compared to the infected control (B) ( p < 0.05).

Our quantitative Z-scores showed a strong and highly significant correlation with the expert's clinical ratings (Spearman's ρ = 0.866, P < 0.0001).

Statistical significance (P < 0.05) was achieved for 222 spots being differentially expressed in inflamed versus non-inflamed mucosa, and of these 39 spots were highly significant (P < 0.0001).

There was a highly significant progression towards more complexity, with lower Bloom's scores in Cycle 1 relative to Cycle 2 (mean difference = 0.42, Wilcoxon rank sum test W = 2044567, P < .0001), and lower in Cycle 2 compared to Cycle 3 (mean difference = 0.84, W = 120920, P < .0001).

The results of Experiment 1 are highly significant ( p < 0.0001), and suggest that the difficulty in perceptually synthesizing a coherent amodally completed surface impaired the ability to detect depth differences in the display containing the alternating red and blue cycles.

Blood elevation of GST-π, DJ-1, NT-proBNP, NDKA and IL6 in stroke patients were highly significant ( p<.0001 ).

As a cross-check, calculated (via DIC and TA) and directly measured pH values were compared and showed a highly significant correlation and no outliers (pH (total scale) = 0.9176 pH (NBS) +0.5453; r 2 = 0.99; p<0.0001).

Moreover, comparing pre-intervention assessment to 12 month (during treatment) assessment yielded that the improvement in all of the assessed indices was highly significant (p < 0.0001) for Visual Acuity, BUT, and Schirmer test for both eyes.

A highly significant increase in area under the ROC curve from ∼0.944 to >0.97 (p<0.0001) was noted upon addition of the ‘new’ tests and thereby established their positive impact on TBM diagnosis ( Figure 4 ).

This difference was highly significant ( P <0.0001).

The superior performance of SHuffle strains ( Fig 1 ), supported by highly significant ANOVA results (F (11,24) = 45.32, p < 0.0001), validates recent emphasis on engineered redox systems for disulfide-rich proteins [ 44 ].

agulhensis had a negative and highly significant Fu's F S test (−22.82, P<0.0001); C. sinicus was also negative and significant (−7.29, P = 0.008).

Results Variation in Cocoa Butter Fat Levels and FA Composition Extensive variation was found in the progeny of the MP01 population: The effect of genotype was highly significant in the MANOVA ( p < 0.0001) with Wilk’s λ = 0.01 and in the univariate case and was found to be significant in all the FAs and percentage of fat content ( Table 1 ).

One-factor ANOVA revealed a highly significant effect of orientation, F (3, 51) = 85.06; p < .0001.

Actual renal clearance during subnormothermic machine perfusion, however, yielded a much closer and highly significant correlation ( r 2 = 0·82; P = 0·0001) with ulterior kidney function upon reperfusion.

According to the ANOVA results, quadratic regression models with response values of TPC, TFC, and DPPH were subjected and the findings revealed that the three models were highly significant ( p < 0.0001).