“highly significant”

This difference is highly significant ( t = −4.41, p < 0.0001) and depends on the fact that differences between motor patterns resulted very salient, whereas it was more difficult to distinguish hand postures.

At this stage, IQ was a highly significant positive predictor (B = 0.350, β = 0.497, t = 4.56, p < 0.0001), while sex was not significant ( p = 0.614).

We conducted a subgroup analysis excluding patients with CKD to compare high versus low calcification groups, and the results were highly significant with a P value <0.0001.

Statistical analysis for color strength (Two-Way ANOVA with interaction) Statistical analysis provided in the Table 5 confirm that (a) Fabric type has a significant effect on K/S ( p < 0.001), (b) Binder ratio (gelatine: alginate) has a very strong and highly significant effect ( p < 0.0001), (c) Dye concentration significantly affects K/S ( p < 0.0001), and d) There is also a significant interaction between fabric and ratio ( p < 0.001), meaning that the effect of the binder ratio depends on the fabric type.

There was a highly significant correlation between the amount of BECN1 and PIK3C3 ( Fig. 7D , R = 0.86, p<0.0001) in agreement with their combined role in forming the autophagy inducing PI3K complex.

A highly significant relationship was seen exclusively in the male group (R 2 = 0.58; linear regression; p < 0.0001) and not in females (R 2 = 0.009; p = 0.68) or in Turner patients (R 2 = 0.076; p = 0.36).

The third group (GR3) included GSTP-1, H-FABP, TNF-α, IL-1β, IL-6, IL-10, CXCL8 and CXCL10, for which the difference between stages was highly significant ( p <0.0001, Mann-Whitney U test) ( Figure S2 ).

However, these differences might be expected if the PH assumption is violated; each prognostic factor had highly significant tests for PH assumption violation based on Schoenfeld residuals in model (c) ( P <0.0001).

5b and D ) indicate that the HFS-fed rats and the rats in all of the treatment groups exhibited highly significant downregulation ( p < 0.0001) of adipose tissue PPARγ expression compared with that in the SD-fed rats.

mansoni cysteine peptidases, leading to consistent and highly significant ( P < 0.0001) 50–83% protection of outbred mice against S. mansoni challenge infection ( 15 ).

MAIN RESULTS AND THE ROLE OF CHANCE A highly significant correlation was found between transcriptional profiles of endometrial biopsies and pairwise UF-EV samples (Pearson’s r = 0.70 P < 0.0001; Spearman’s ρ = 0.65 P < 0.0001).

The differences between control and TIUKO CF rats was highly significant (p < 0.0001) Discussion The development of the TIUKO procedure permits the examination of mid-gestation developmentally required genes in the absence of both early lethality and compensatory mechanisms that ameliorate the final disease phenotype.

A one-way ANOVA revealed a highly significant effect of formulation on swelling (S w ) (F(7, 792) ≈ 43,176, p < 0.0001), with a very large effect size (η2 ≈ 0.997).

Comparison of normal mucosa, tumor-adjacent mucosa, and tumors disclosed a strong and highly significant (p < 0.0001) up-regulation of EpEX in tumors with median IHC scores of 220 versus 60 and 50 in tumor-adjacent and healthy mucosa, respectively (Fig. 1d ).

During perifusion of both the whole spinal cord and the cervico-trigeminal area, the interaction between the two factors of variation was found to be highly significant indeed (F 1-27 = 24.33 and F 1-22 = 30.17, respectively, p<0.0001; Table S1 ).

We therefore performed one-way MANOVAs which showed highly significant differences among vegetation types within the tropics ( F 2,67 = 27.33, P < 0.0001) and the temperate zone ( F 2,55 = 6.54, P = 0.003), and in the combined analysis ( F 5,122 = 14.5, P < 0.0001).

When conservation of N- acetylated CysLys pairs relative to non-acetylated CysLys pairs was plotted against the maximum lifespan of 52 mammal and bird species, there was a highly significant negative correlation (p < 0.0001) and no significant correlation for N- acetylated cytosolic SerLys pairs (p = 0.32; Figure S3 A).

Genetic differentiation among the sub-clusters was highly significant ( P < 0.0001).

The pair group comparisons of day 7 v/s day 15, day 45, and 6 months showed a highly significant difference of 0.64, 1.48, and 1.80, respectively, and P value = 0.0001.

By 12 months, however, a highly significant ( P <0.0001) increase in input resistance occurred.

For qPCR, the concordance correlation coefficients (CCC) for all pairs (A–B, A–C and B–C) exceeded 0.95, with highly significant Pearson correlations ( p < 0.0001), confirming strong concordance.

Not only are the correlations highly significant for infected implants in statistical terms (e.g., P <0.0001 for CCR5 + ITTP versus both Gag-p24 + ITTP and thymocyte viability), but the proportion of CCR5 + ITTP corresponds closely to that of infected ITTP ( Figure 4A ).

Analysis of extensive data pooled from three independent experiments revealed that on day 28 post-transmission, the neutrophil depleted, ALM+CpG-vaccinated mice showed a highly significant reduction in parasite load compared with neutrophil depleted, naïve mice (p<0.0001), as well as control treated, ALM+CpG vaccinated mice (p = 0.002), and indistinguishable from that in healed animals ( Figure 4D ).

The highest percentage of kidney pathology in PCR‐positive fish was detected in the 0+ fish age class (85%), this category shows a highly significant difference compared with age categories 1+, 2+ and 3+ ( p < 0.0001), whereas no significant differences were detected among the remaining groups (Table 1 ).

Most importantly, the LC3-II/LC3-I ratio, which measures autophagy activity, showed a highly significant increase in the iridocorneal region of the aging mice ( 4 months: 1.106 ± 0.21, n = 5; 18 months: 2.178 ± 0.10, n = 4; P < 0.0001, t -test) ( Fig. 2 C).