“highly significant”

Comparing all of these subjects, a highly significant correlation [ N = 34; R = (−)0.68; p < 0.0001] was found between RBC deformability and the level of HDPs.

Results We find a highly significant positive correlation between Pfirrmann grades and the gene expression of MMP1 (r=0.67, p=0.0001), MMP3 (r=0.61, p=0.0002), MMP10 (r=0.6701, p=0.0001), MMP13 (r=0.48, p=0.004), ADAMTS1 (r=0.67, p=0.0001), and ADAMTS5 (r=0.53, p=0.0017).

It is also plausible that these inconsistent results are due to the relatively small sample size in MRI studies, as a related clinical study from TREND with a much larger sample size ( N = 661) revealed a highly significant and slightly stronger correlation between TMT B-A and DT gait speed while subtracting ( p < 0.0001, r = 0.27) ( Hobert et al., 2017 ).

Statistical analyses revealed that this elevation was small (14.5 μg/g) but highly significant ( p -value < 0.0001).

This showed that Ca 2+ -dependent trafficking was highly significant (Mann-Whitney test: p<0.0001; Figure 3C ).

amylovora population values were smaller in R1 (of around 0.6 orders of magnitude) than in R2 (around 1.6 orders of magnitude) but highly significant in both experiment repeats ( p < 0.0001).

Treatment was highly significant for TMAO concentrations ( P < 0.0001) and yields ( P < 0.0001), where colostrum from both CHOL45 and CHOL30 cows had greater concentrations (both comparisons, P < 0.0001) and yields (both comparisons, P < 0.01) than CON.

Results We observed a highly significant correlation between the storage time of pRBC units and a drop in pH, as well as an increase in potassium and lactate of stored red cells ( p < 0.0001).

Abnormal renal function tests (higher levels of serum urea and creatinine) were reported in our study and the difference was found to be highly significant (urea (p<0.0001) and creatinine (p=0.0019)) between the controls and cases.

In patients treated with complete surgery, OS was 318 months, compared to 191 months in those who underwent partial surgery and only 19 months for those who underwent only one biopsy procedure; these differences were highly significant (p = 0.0001).

In the active rTMS group, the mean number of correct answers on the PRM test increased by 4.54 ± 2.98 from baseline to week 8, while the correct number in the sham group decreased slightly (-0.92 ± 2.72) and the difference between these changes was highly significant (mean 5.46 ± 0.92, 95%CI: 3.43–7.14, F = 33.3, df = 137, P < 0.0001, effect size = 0.474) (Table 2 ).

Lastly, analysis of the relative usage of pAs in 182 genes that displayed significant modulation of at least two alternative pAs ( Supplementary Table S7 ) highlighted a highly significant negative correlation between the abundance of the two APA isoforms for most genes (92.85%; r = –0.8936, P <0.0001, Pearson correlation; Figure 2F ), thus confirming the effect on transcript lengthening induced by HT.

We found a highly significant reduction in ovary mass (linear mixed model; t = − 4.37, df = 104, p < 0.0001) in failed queens across surveys (Supplementary Table S1 and Fig. 1 a), indicating that small ovaries are a widespread phenotype associated with poor fecundity, as described by beekeepers.

Moreover, vaccine product and DMT class were highly significant predictors of antibody responses ( p ≤ 0.0001) for both assays and age was a significant predictor on Elecsys ( p = 0.0003) and MBI ( p = 0.026) assays.

Highly significant differences in MICs and MBCs distribution between fluoroquinolones ( p < 0.0001) were observed, and pradofloxacin showed the lowest MICs and MBC ( p < 0.0001) when compared with the other FQs tested. 2.2.

The difference in SHM in the long prime (week 29) versus 10 week prime was highly significant ( P < 0.0001 by Mann–Whitney, Fig. 4b ; P < 0.0009, Fig. 4c ), and the difference in median mutations between weeks 10 and 29 was as great as that between weeks 4 and 10, indicative of robust GC functionality continuing through to at least week 29 (Fig. 4a–c ).

The results confirmed that the overall model was highly significant ( p < 0.0001) for all catalysts and both dyes, 45 indicating that the selected variables strongly influenced degradation efficiency.

In contrast, treatment with 10 μg mL −1 ASL resulted in a highly significant decrease in the proportion of the total scratch area covered in HT-29 (10%; p < 0.0001) and HT115 cells (22%; p < 0.0001) after 72 h (Fig. 2a ).

Especially the JFM average patterns attain a very strong and highly significant correlation of r = 0.98 ( p = 1.0 × 10 - 4 ).

To statistically assess the overlap between the two gene sets, we performed a Fisher’s Exact test, which demonstrated a highly significant concordance (P < 0.0001, two-sided), indicating that the shared transcriptional response is unlikely to occur by chance (Supplementary Table S1 ).

Comparative statistics (Friedman test) indicated that the differences between the groups are highly significant (P < 0.0001) ( Fig. 1 C) even after only the first 3 months of treatment with Alxoid.

Results There was a highly significant difference in respiratory aerosol concentrations between SARS-CoV-2 PCR-positive (median 1490.5/L) and -negative subjects (median 252.0/L; p < 0.0001).

In the regression analyses to adjust M (with M = 0 recorded as missing) for covariate effects, gender was highly significant ( F = 115, p < 0.0001).

Friedman's analysis of variance revealed that there was a highly significant variation at all frequencies (p = 0.0001).

In both the citalopram and pramipexole groups, the BDI score showed a highly significant decrease with a large effect size ( r ≥ 0.6) analyzed by a Wilcoxon signed-rank test ( Z = −4.018, P < 0.0001, and r = −0.877 for citalopram group and Z = −3.926, P < 0.0001, and r = −0.878 for pramipexole group).