Results We observed a highly significant decrease in the presence of the KIR2DS2 and KIR2DS4 genes (OR = 0.15, 95% CI = 0.05-0.41, P = 0.0001; OR = 0.06, 95% CI = 0.02-0.2, P = 0.000, respectively) and in the presence of the KIR2DL5A gene (OR = 0.05, 95% CI = 0.02-0.14, P = 0.0000) in the TC group compared to the HC group.
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Chi squared test showed that there is a highly significant temporal difference in the proportion of blood meals from American Robin and Northern Cardinal (p<0.0001).
officinalis extract alone displayed a highly significant ( P < 0.0001) increase in the catalase activity compared to the infected group, which highly decreased in comparison to the healthy group ( P < 0.0001), restoring CAT activity nearly to the levels observed in the normal control group, with no statistically significant difference ( P = 0.9).
The reliability between the 2 readers was highly significant ( P < 0.0001).
Our findings uncovered a highly significant effect of MS ( p < 0.0001).
On the contrary, in WB-irradiated mice, the average percentage of apoptosis was 14.5% ± 0.76, a highly significant value compared to the unirradiated group ( p < 0.0001; Figure 7 a–e).
This difference between cDNA and gDNA is highly significant for each replicate: (Family 1: ANOVA, F 1,6 = 443.36, p<0.0001; Family 2: F 1,6 = 39.60, p = 0.0007; Family 3: F 1,6 = 219.02, p<0.0001).
Among tortoises in the genus Chelonoidis ( Table 1 ), highly significant differences ( p < 0.0001) were found in overall positivity and for the detected virus types between the different species, with a remarkably high positivity rate in Argentine tortoises (28.57%, 90% of which were TeHV1) compared to all of the other Chelonoidis spp. tested.
One-way ANOVA ( Tables S1 and S3 ) further indicated that the overall model was highly significant ( p < 0.0001), with experimental data closely fitting the predictive model.
The genetic differentiation among the populations was high (F ST : 0.28) and found to be highly significant ( p < 0.0001).
Overall, the model was highly significant with an adjusted R 2 of 0.54 ( p -value <0.0001).
Three weeks post- Mtb challenge (week 11), the increase in body temperatures in unvaccinated animals was significant relative to BCG-vaccinated ( P <0.01) and highly significant relative to MtbΔ sigH -vaccinated animals ( P <0.0001; two-way ANOVA with Tukey's correction; Fig. 2b ).
Kaplan-Meier analysis showed highly significant retardation of progression for trametinib or the combination (p<0.0001 vs. vehicle), but not for single agent pazopanib ( Fig. 2C ).
A highly significant positive correlation existed between FDK and DON/NIV content ( R = 0.84, P < 0.0001).
The complement pathway consists of a cascade of protein activation, centered around C1q, the three components of which (C1qa, b, and c) are up-regulated at symptomatic and further at late-stages in our microarray of astrocytes with C1q and C4b showing the most highly significant differential expression ( p ≤ 0.0001) of all dysregulated genes at late stage disease.
This analysis showed highly significant ( P < 0.0001) effects for genotype, temperature, ploidy level, and for the three possible two-way interactions ( SI Appendix , Table S3 ).
It was found by flow analyses ( Figure 7B ) that NAV-duplexes were strongly recognized by IgG1-DS5 on biotin-labeled cells, with no such signals arising from NAV alone [highly significant by t -test analysis (Methods); p <0.0001].
The repeated measures analysis of feather brightness resulted in a final model that included highly significant effects of exposure time ( F 1,590.44 =26.09, P <0.0001) and pigment identity ( F 1,514.84 =4.06, P =0.044).
This difference was highly significant with a large effect size ( t (119) = –5.6, p < 0.0001, d = 0.98).
Statistical analysis of GRP78 expression confirmed a highly significant reduction (**** p < 0.0001) in GRP78 intensity in GFAP astrocytes (Fig. 10 D) and NeuN neurons (Fig. 10 E) of TG2 KO samples.
Myostatin inhibition had no significant effect on BMD from DEXA either on the ground or in flight; however, time following launch was highly significant (p < 0.0001) and time was interactive with spaceflight (p < 0.0001) but not myostatin inhibition treatment.
Discrimination of the morphs was highly significant (Wilks’ λ = 0.02, F 21, 73 = 9.02, p < 0.0001; Fig 3 ), and canonical variables 1 and 2 explained 60.8% and 30.9% of the variation in female throat colouration, respectively.
Accordingly, spearman correlations between p-S65-Ub and PRKN protein levels in WT, Prkn +/- , and prkn -/- brains were positive and highly significant ( r = 0.72, p < 0.0001) (Fig.
Interestingly, seven out of the 110 genes present in the four high-scoring sub-networks were from the 263 genes mapping to bands q11 and q12 on chromosome 22 ( Figure S31 ), which is a highly significant enrichment ( p < 0.0001).
Consequently, when in vivo and ex vivo periods were plotted together, the control groups exhibited a highly significant within-animal correlation, but the VPAC2-Cre/ Ck1ε Tau/– group did not ( Fig. 2 D ; Pearson correlation, Controls: r = 0.923, p < 0.0001, VPAC2-Cre/ Ck1ε Tau/– : r = 0.598, p = 0.07).