“highly significant”

Three weeks post- Mtb challenge (week 11), the increase in body temperatures in unvaccinated animals was significant relative to BCG-vaccinated ( P <0.01) and highly significant relative to MtbΔ sigH -vaccinated animals ( P <0.0001; two-way ANOVA with Tukey's correction; Fig. 2b ).

The difference in spatial selectivity between the two brain areas was highly significant ( p < 0.0001).

However, the difference in the predicted probability between the intrinsic subtypes was still highly significant for both the primary and validation datasets ( P <0.0001) (Figure 4D , 4E ).

qRT-PCR again showed a reduction in PDS mRNA levels in plants infected with BSMV-BdPDS compared to BSMV-GFP 375 , the difference being highly significant ( p < 0.0001) (Figure 5B ).

Results of multivariate analyses showed highly significant effects of flow [Pillai’s V = 0.579; F(3,255) = 116.9, P<0.0001] and of speed [Pillai’s V = 0.367; F(12,771) = 8.95, P<0.0001].

Differences in weight losses between groups were highly significant ( P <0.0001) throughout all 4 years of follow-up.

The negative association between the minimal doubling time and the average number of prophages per host genome was highly significant in this much larger data set (Spearman's ρ =−0.36, P <10 −4 ), independently of host genome size ( Supplementary Figure S7 and Supplementary Table S2 ).

A highly significant difference in susceptibility between GM and WM was observed for both SC QSM approaches ( p < 0 . 0001 ), confirming that both methods preserve expected tissue contrast. 3.2 Application of SC QSM to MS Patients SC QSM was applied to a group of 20 people with MS.

Intriguingly, the sorted IFNβ + Tip-DCs also stimulated the naïve T cells to proliferate in a highly significant manner (p < 0.0001 as compared to macrophages) and more efficiently than the sorted IFNβ/YFP − bona fide Tip-DCs ( Figure 6 ).

During SMC differentiation of A404 cells, 72 (55.4%) of these genes showed significant differential regulation, pathway over-representation that was highly significant by Fisher's Exact Test (p<0.0001).

In males, the difference was highly significant (547.67 ± 19.77 vs. 449.35 ± 13.34, p < 0.0001), and a comparable trend was observed in females (352 ± 16.73 vs. 316.31 ± 11.22, p < 0.0001).

The t -test applied for ABIM versus NIM and ABMA versus NMA yielded highly significant result with P < 0.0001*.

Such a latitudinal trend was confirmed by the highly significant negative correlation observed between latitude and allelic richness (r = −0.57, P<0.0001); no significant correlation was found between longitude and allelic richness (r = 0.036, P = 0.892).

Of the protein peak clusters found to be differentially expressed between the two groups, apolipoprotein A-II was found to be highly significant ( p < 0.0001) and double-loop classification analysis of the differentially expressed protein clusters demonstrated a mean prediction accuracy and specificity of 88% in separating brain tumor patients from controls.

Results: A significant improvement was noticed in the somatic, urogenital, and psychological climacteric symptoms from baseline to 6 weeks ( P = 0.001) and a highly significant improvement after 12 weeks ( P = 0.0001) of treatment. 96.5% of patients were satisfied with the treatment outcome evaluated by the MS-TSQ.

The complement pathway consists of a cascade of protein activation, centered around C1q, the three components of which (C1qa, b, and c) are up-regulated at symptomatic and further at late-stages in our microarray of astrocytes with C1q and C4b showing the most highly significant differential expression ( p ≤ 0.0001) of all dysregulated genes at late stage disease.

While comparing between two groups a statistically highly significant difference found between the groups ( P < 0.0001) and group C maintains hemodynamics more steadily than group G.

Linear regression analysis revealed a highly significant positive correlation ( r = 0.2426, P < 0.0001).

Comparing methods, the improvement in correlation to logarithm concentration of ln C obs ( t ) and ln C Model ( t ) was highly significant ( p < 0.0001) for Tk-GV functions compared to the E1 functions using paired samples t -testing of the z -values from z = atanh( r ).

This difference in prevalence was highly significant ( P < .0001).

In cohort 2, the survival curves revealed a highly significant association between risk of both mortality endpoints in the follow-up period and all three biomarkers, with a p<0.0001, except for p CV = 0.00016 for PRO-C6 (Figure 3 ).

The overall effect test result is highly significant ( z = 4.17; p < 0.0001), underscoring a consistent and statistically significant difference favouring the group with disabilities.

The initial value of an index at age 40 (“ I n t e r c e p t 40−60 ”) is also a highly significant ( P < .0001) risk factor for mortality for HC and PP (i.e., higher values of respective index at age 40 correspond to higher risk of death compared to smaller values of this index), being nonsignificant for BG.

Statistical analysis revealed a highly significant positive correlation between serum vitamin D and calcium levels ( p <0.0001) ( Figure 1 ).

The results demonstrated that the model is highly significant ( P < 0.0001, F = 273.5) with a non-significant lack-of-fit ( P = 0.6251), confirming the adequacy and excellent fit of the model.