“highly significant”

A highly significant correlation of cytoplasmic survivin staining was observed with higher Gleason Scores and advanced pT stages (p < 0.0001 each, Table 1 ).

The difference of CRP between the groups was highly significant ( P < 0.0001).

A multivariate analysis of variance showed that while role had a highly significant effect ( p < 0.0001) on the content of the communications, neither gender nor the order in which roles were assumed had a significant influence.

The overall model was highly significant ( P < 0.0001) and showed substantial fit ( R 2 = 0.8684) ( Fig. 5E ).

Notably, in selenate-treated Tg animals, retention memory was restored to WT levels, resulting in a highly significant effect of treatment ( Figure 3 , post hoc Dunnett tests for vehicle-treated Tg compared to the other three groups p = 0.0001).

Intragroup comparisons were highly significant (P < 0.0001), confirming effective microbial control.

In fact, cosinor periodogram revealed that below 74 years the rhythm was not statistically significant neither for Clock and Per1 ( p > 0.17 and 0.37 respectively) although above 74 years it was highly significant for the three genes ( p < 0.0001).

The difference among the groups was highly significant ( P < .0001).

Furthermore, a highly significant reduction was noted in IL-17-expressing cells across all three probiotic groups (DCF0420 P < 0.0001; DCF0514 P = 0.0001; DCF0620 P < 0.0001) compared to untreated colitis controls.

For all interactions, the global null hypothesis test was highly significant ( P ‐value < .0001).

Upon analysis, it is found that the regression model for the 4-antinodes vibration mode frequency value y 1 is highly significant, with F-value = 97,959.40, p -value < 0.0001.

The difference between the two groups was highly significant (Mann–Whitney Rank Sum test p = 0.0001).

Heterogeneity testing was highly significant ( p < 0.0001).

truncatus consistently and reproducibly correlated with snails showing highly significant (up to P < 0.0001) decrease in soft tissue and hemolymph content of the monounsaturated fatty acid, oleic acid, and the polyunsaturated fatty acids, linoleic, and arachidonic acids as compared to naïve snails.

Main Effects of Stress Factors on MigraineID All three stress factors (CHA, RLE, FINANC) showed highly significant ( p < 0.0001) main effects on migraineID with more severe stress increasing the prevalence of migraineID.

The observed differences in survival were highly significant both for OS and PFS (Log-rank test; P <0.0001 each).

A highly significant linear correlation ( p < 0.0001) was observed between the mean CT numbers (HU) of each of the thirteen phantom tubes and the increasing concentrations of iodine ( Fig. 2 , Supplementary Table 1 ).

During the post-Ebola period, there was a highly significant reduction in case-fatality for the first three morbidities compared to the pre-Ebola period ( P <0.0001).

By this criterion, protection was highly significant (Fisher’s exact test, P < 10 −4 ) at any given threshold less than 10,000 CFUs (Extended Data Fig. 8b ), with the IV BCG group showing 90% protection (95% confidence interval: 60–98%) at a threshold as low as 50 CFUs.

The results revealed a highly significant positive correlation between chronotype assessed by both parameters (n = 3240; Pearson correlation coefficient r = 0.327; P < 0.0001) (Fig. 1a ), confirming relevance of data and methodology used to assess chronotype in this study.

Together, these results depicted that the obtained linear model was highly significant ( p -value < 0.0001) and a lack of fit showed no significance ( p -value > 0.05).

Additional association analyses of LCN2 and MMSE scores including all groups with cerebrovascular disease (SVDND, VCIND, and VaD) showed highly significant negative correlations in cohort 1 (cc = −0.55, p < 0.0001, Fig. 3c , Spearman correlation test) and cohort 4 (cc = −0.56, p = 0.008, Fig. 3d , Spearman correlation test).

The main effect of group was highly significant [ F (1, 83) = 174.84; p < 0.0001].

Results: A highly significant difference ( P < 0.0001) was found in the MMP-9 concentration between the Groups A (27.56 ± 2.87 ng/ml) and B (17.16 ± 1.74 ng/ml) and between Groups A and C (14.13 ± 2.87 ng/ml).

After adjustment for multiple factors, margin width was a more highly significant predictor of IBTR ( P < .0001). 22 The MP felt that, overall, the heterogeneity of the evidence between the above-reported studies did not allow for a definitive recommendation for margin widths greater than 2 mm in patients foregoing RT.