In the treatment group, the mean change in the primary endpoint (hours daily OFF time) from baseline to EoS was highly significant [−1.07 (SD 0.78) vs. + 0.09 (SD 0.35), p < 0.0001] ( Table 3 ).
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Quantitative analysis confirmed highly significant differences between NPM1wt and NPM1c+ cells in nucleolar rim intensity ( P =0.0001) ( Fig. 3B ) and nucleolar circularity ( P <0.0001) ( Fig. 3C ).
The mean age at death for animals unaffected was 614 days (SEM ± 20) compared to 741 days (SEM ± 18) for animals with pathology; a difference which is highly significant ( p < 0.0001, two-tailed unpaired t test).
However, there was a highly significant increase in DHE-positive cells in cells treated with 7KC and 7β-OH (62.5 μM) compared to the control, vehicles, α-tocopherol, and oils ( p <0.0001).
For values of ACAG below the turning point, the association with BMD was negative, with a β coefficient of −0.006 (95% CI: −0.009, −0.004) and a highly significant P value of <0.0001.
The equation developed through the regression is as follows: Percent cover of ISA = 0.0795 (radiance) + 0.00868 (population count) The regression had an r 2 squared of 0.59 and is highly significant p <.0001.
The deduced quadratic model was highly significant at p value <0.0001 ( F = 33.34, d f = 6) and non-significant lack of fit ( p = 0.9237) (Table 2 ).
In all three studies, the primary endpoint was achieved, with a highly significant reduction in PANSS total score from baseline to endpoint (p < 0.0001).
Among pictures SR enhancement to phobia-related material was highly significant F (1,87) = 28.21, p < 0.0001, η 2 = 0.25, unlike the comparison between noises ( p > 0.10).
Positive effects of favorable alleles have additive effects The study of the correlation between the number of QTLs with NPQTL and DI revealed that in five datasets, both showed a highly significant negative correlation (r = −0.48–0.71, p < 0.0001), with the mean dataset exhibiting the strongest correlation (r = −0.71; p < 0.0001) ( Supplementary Figure S3 ).
Transgenic animals treated with the high dose of galantamine showed a highly significant lower number of plaques in both areas compared to untreated control mice (p≤0.0001 according to ANOVA) ( Figure 6 , 7 ).
The findings demonstrated a substantial prevalence of dental fluorosis, with a highly significant difference observed between primary and permanent dentitions and BMI categories (p < 0.0001).
These two tests reveal a highly significant difference (P< 0.0001) between the values of wing-shaped Procrustes in the females of the three species ( Table 3 ).
FT wAUROC was also highly significant in 141 patients with diabetes 0.80 (0.78–0.82; P<0.0001).
Moreover, vaccine product and DMT class were highly significant predictors of antibody responses ( p ≤ 0.0001) for both assays and age was a significant predictor on Elecsys ( p = 0.0003) and MBI ( p = 0.026) assays.
Haplotype frequencies for each group and each highly significant block ( p < 0.0001) were calculated using a custom R script. 2.6.
Results Highly significant differences were found across all functional scores and range of motion among classification groups ( P < .0001).
A highly significant inter‐patient variation in annual progression rate was detected (variance of β r 0.893; p < 0.0001).
Lukenda et al [ 48 ] studied transient elastography (TE) in 52 KTRs and reported a highly significant negative correlation of kidney allograft stiffness on SWE with eGFR in 52 KTRs ( r = -0.640; P < 0.0001).
ART to a beep was very highly significant (p < .0001, d = 0.94) (Table 3), demonstrating a large effect size and highlighting a substantial impact of intervention on ART.
In our study there was a highly significant difference in METS of sedentary and non-sedentary individuals ( P < 0.0001).
However, there was still a positive and highly significant covariance between the male and female partner's in tGSH and GSSG ( n = 340, tGSH: F = 22.163, P < 0.0001; and GSSG: F = 5.955, P = 0.015).
The correlation of the DEC1-dependent signature was highly significant with the CD28-regulated gene list (P < 0.0001). 72% of the genes up-regulated by DEC1 were also up-regulated by CD28 co-stimulation, whereas 83% of the DEC1 down-regulated genes were again down-regulated by CD28 signaling ( Fig. 7, C and D , top).
Results We observed a highly significant correlation between the storage time of pRBC units and a drop in pH, as well as an increase in potassium and lactate of stored red cells ( p < 0.0001).
In subsequent visits up to the fifth visit, both chlorpromazine and risperidone showed a gradual decline in the mean score of the symptoms to the extent of 20 for chlorpromazine and 14 for risperidone, which were highly significant ( P =0.0001).