“highly significant”

The difference between the two rates was statistically highly significant ( P <0.0001).

There is a highly significant increase in age, in positive BRCA1 group; compared to negative BRCA1 group (p < 0.0001) while a non-significant difference as regards all the remaining basic clinical data (history of breast cancer, laterality, presenting symptoms and CA125 level) (p > 0.05) was found.

However, important highly significant risk factors of oocyst shedding of calves was an age of less or equal than 20 days (OR = 7.4; 95% CI 95% = 3–16; P < 0.0001) and occurrence of diarrhea (OR = 5.5; 95% CI 95% = 2–11; P < 0.0001).

The correlation was highly significant (p < 0.0001) for both red cones (LWS) R 2 = 0.9934 (software count versus manual count y = 0.981x + 10.9, data range 527–1656) and green cones (MWS) R 2 = 0.9907 (software count versus manual count y = 0.986x + 27.7, data range 684–1689).

As displayed in Table 1 , results revealed that the fitted model was highly significant ( p < 0.0001), indicating that it could effectively explain the variation in the yields of YKP ( Wu et al., 2021 , Wu et al., 2022 ).

The ANOVA results indicate that the selected model was highly significant ( p < 0.0001), while the lack-of-fit term was not significant ( p > 0.05).

Subsequent analysis of TNFSF4 mRNA levels showed that oar-miR-125b overexpression led to a highly significant downregulation ( p < 0.0001), whereas its inhibition resulted in a significant upregulation ( p < 0.001), compared to the NC group ( Figure 3 B).

Overall, the results demonstrated a highly significant reduction (**** p < 0.0001) in nitrite production when macrophages were treated with L. pedunculata and T. mastichina .

The result was reported as highly significant with p < 0.0001 (statistical method not specified [ 33 ]).

The log‐rank tests were highly significant ( P <0.0001), and the graphs illustrate a trend for higher mortality and higher probability of the composite renal end point by increasing cfPWV quartile.

The study successfully captured significant longitudinal trends in both humoral and cellular immunity, including a highly significant decline in anti-spike IgG antibodies ( P <0.0001) and group-wise differences in IFN-γ levels ( P =0.0299), indicating the robustness of the cohort size and design.

LDL-C reductions within each treatment, either as absolute values or expressed as ratio of the initial value, were highly significant ( p < 0.0001).

Statistical Analysis All four ALC quadrants were shown to have a statistically significant improvement in visibility between alive and after life conditions ( Table 6 ), with a highly significant overall linear mixed effects model (overall P < 0.0001).

However, there was also a highly significant difference in mean age between the groups (Fig. 7B ; P < 0.0001, power 99%).

The exact G test for differentiation indicated that, on average, differences in allele frequency distribution among populations were highly significant (exact p value ≤0.0001).

The MANOVA test showed a highly significant fit [ F Wilks’ lamb d a (45,785.057) = 24.05, p < 0.0001, η 2 = 0.58].

70 The expression of pEGFR was investigated in recurrent NFPAs (n=47) and in non-recurrent NFPAs (n=55), and a highly significant difference was reported (p<0.0001). pEGFR positivity was greater in a higher number of recurrent NFPA and the H-scores were also higher in recurrent NFPA compared with non-recurrent (117 ± 6.0 versus 71.2 ± 3.7; p<0.0001). 17 The H-score is determined by adding the results of multiplication of the percentage of cells with staining intensity ordinal value (scored from 0 for 'no signal' to 3 for 'strong signal') with 300 possible values.

Although storage duration alone had no significant main effect, the effect of time was highly significant at both time points ( P < .0001), reflecting distinct recovery and clearance profiles over time ( Figure 5 E-F; supplemental Table 3 ).

Biological control of Sclerotium rolfsii causal agent of rot in pumpkin fruit in vitro For the three samples of the pathogen growth colonies, the mean values showed highly significant differences ( P < 0.0001 and P = 0.0042).

4(b )). Effects of age and polyphenol-rich extract from grape and blueberry-enriched diet on hippocampal neurogenesis A two-way ANOVA on the number of DCX-IR cells revealed a highly significant age effect ( F (1,34) = 340·491; P < 0·0001), but no diet effect ( F (1,34) = 1·167; P = 0·2876) or age × diet interaction ( F (1,34) = 0·760; P = 0·3896), indicating that, irrespective of diet, aged mice have fewer newly generated immature neurons than adult mice ( Fig. 5(a )).

A total of 220 patients completed this 24-week study, and highly significant differences in the total number of gadolinium-enhanced T1 lesions were observed in both ocrelizumab groups ( p < 0.0001) at weeks 12, 16, 20 and 24 when compared with the placebo group.

Highly significant (p < 0.0001) and close (Spearman r = -0.91) correlation between binding affinities determined by SPR and the mol% binding determined in the pull-down assays was observed for the interactions of both wild-type (closed symbols) and ΔH C loop-mutant (open symbols) H C B (triangles), H C DC (squares), and H C G (circles).

We found that full spectrum SEF95 showed highly significant differences between pre- and post- LOR ( p < 0.0001).

All factors were therefore taken forward into a multivariable model and again all factors were highly significant (all p < 0.0001) (Table S 7 ).

The CK19 analysis helped us to exclude adenocarcinomas versus tuberculosis, transudates, and parapneumonic effusions with a highly significant P value (Dunn's test, P < 0.0001), as shown in Table 2 .