Group classification using the support vector machine (SVM) Overall, the set of 12 variables achieved good classification accuracy (81%), sensitivity (78%), and specificity (85%), and each of these were highly significant compared to chance simulations using permutation tests (accuracy P = 9.99 × 10 −5 ; sensitivity P = 9.99 × 10 −5 ; specificity P = 6.99 × 10 −4 ).
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The dissimilarity metrics, measured separately with Bray-Curtis, Jaccard, and Jensen-Shannon (JSD) indices with 10,000 permutations, were all highly significant (PERMANOVA, p = 9.999e-05), representative of the centroids being different between the two groups.
Beta diversity among sampling years was highly significant for all bird species ( n = 167, R = 0.175, P = 9.999e −05 ; Supplementary Fig. 8c ) and when subsetting by only sandhill cranes ( n = 122, R = 0.106, P = 9.999e −05 ), but not when subsetting for only non-crane bird species ( n = 45, R = −0.70, P = 0.905).
S3 and S5 gave highly significant increase in solubility with p < 0.0001 with no significant difference between them ( p = 0.6891, > 0.05), which means this method was more efficient in the complex formation.
As shown in Figure 3 , rEg.P29 alone did not induce a significant increase in specific IgG at 20 weeks post-immunization, whereas the formulation with Quil A adjuvant elicited a highly significant increase in rEg.P29-specific IgG ( P < 0.0001), confirming that Quil A is essential for inducing a robust IgG-dominant humoral immune response in sheep.
Although the linear effect of saponin concentration was not statistically significant (F = 3.39, p = 0.0814), the quadratic effect was highly significant (F = 117.50, p < 0.0001), confirming the curvature of the response.
Notwithstanding the smaller sample size at FP + 14, the platelet increase observed at FP + 14 was highly significant (p < 0.0001).
As expected, the co-precipitations of Cul4A and Cul4B with the viral accessory proteins showed a highly significant ( p < 0.0001) positive correlation (Figure S4C ).
Analysis of these data by Fisher’s exact test showed that protection was statistically significant in each individual study (group 1, p = 0.025; and group 2, p = 0.003), while the combined results were highly significant ( p < 0.0001), demonstrating the efficacy of Emulsigen as an adjuvant in this system.
In contrast, the relationship between the human and sloth SPDs is positive and highly significant ( r s = 0.35, P < 0.0001), suggesting those populations fluctuated together from extrinsic factors.
Nutrient addition effects on moss-associated N fixation Treatment and sampling time had a highly significant effect on N fixation (p < 0.0001, F = 23.7 and 74.7, respectively), and differences between forest successional stages were also observed (p = 0.017, F = 5.7).
According to Table 3 , the ANOVA for the response surface quadratic regression model showed that the model was highly significant ( p < 0.0001) with a very high F -value (211.56 and 253.50).
There was a highly significant decrease in the number of children requiring rescue analgesic ( P =0.0001) in group D [ Table 4 ].
A clear and highly significant decrease in the total number of B cells was observed within 4 weeks after treatment in the subjects receiving rituximab (p<0.0001), which was followed by a drop in serum levels of IgA-RF, IgM-RF and IgM, reaching the level of statistical significance (p=0.003, p<0.0001 and p=0.001, respectively) at all time points.
The regression and correlation analyses between gestational age and the studied parameters were highly significant ( p < 0.0001).
Effects of treatments on yield and yield components Nutrient treatments had a very highly significant effect on wheat grain yield and thousand-seed weight (p < 0.0001).
The flow cytometry and OpenCASA viability results were compared using Pearson’s correlation test, and a highly significant correlation (P<0.0001) was obtained for viable and non-viable spermatozoa ( Table 5 ).
Effect of location and concentration on susceptibility Larvae GLM revealed a highly significant effect of location (L) on the susceptibility of An . gambiae larvae to P . guineense (F 9, 177 = 2441.18 p < 0.0001) and E . aromatica (F 9, 177 = 614.88, p < 0.0001).
There was a highly significant difference between the South District and each of the five other districts (p < 0.0001) as follows: Jerusalem (IRR = 0.20, 95% CI: 0.14–0.29), North (IRR = 0.17, 95% CI: 0.12–0.22), Haifa (IRR = 0.18, 95% CI: 0.11–0.27), Center (IRR = 0.14, 95% CI: 0.07–0.23), and Tel Aviv (IRR = 0.11, 95% CI: 0.01–0.44).
The highest percentage of kidney pathology in PCR‐positive fish was detected in the 0+ fish age class (85%), this category shows a highly significant difference compared with age categories 1+, 2+ and 3+ ( p < 0.0001), whereas no significant differences were detected among the remaining groups (Table 1 ).
[ 23 ] identified human population density and total housing units as highly significant predictors of Ae. aegypti abundance (all p < 0.0001).
The value of glcH expression observed at 5 nM glucose was highly significant ( p < 0.0001).
For qPCR, the concordance correlation coefficients (CCC) for all pairs (A–B, A–C and B–C) exceeded 0.95, with highly significant Pearson correlations ( p < 0.0001), confirming strong concordance.
The repeated‐measures ANOVA revealed a highly significant difference among total, dominant, and nondominant mBF (F(2,334) = 136.30, p < 0.0001).
The multiple regression model was highly significant [ F ( F (2, 114) = 117.9, p < 0.0001] and the R squared was equal to 0.67.