The difference of this value with the plateau of neutralizing activity of hospitalized individuals was highly significant (p < 10 –7 by Z-test, and p < 10 –4 by Wilcoxon test as described in methods; Fig. 2 B), and reflects the different distribution (p = 0.0003, Chi-square test) of individuals with undetectable (< 20), low (20–100), medium (100–1000) or high (> 1000) neutralization titers in the non-hospitalized and the hospitalized groups (Fig. 2 C).
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These QTLR presented among the most significant associations in the first scan, and still harbor highly significant associations (p < 1e−7 and 1e−8, respectively).
Selection treatment had no significant effect on the total number of fixed mutations (electronic supplementary material, appendix B figure S14A; ANOVA p = 0.788), but the effect of the ancestor was highly significant (electronic supplementary material, appendix B figure S14B; ANOVA p < 1 × 10 −7 ).
8 , highly significant effects were observed for the factors of eccentricity ( F (1,5) = 2458.257, p = 10 −7 ), and visual area ( F (1.574,7.871) = 107.981, p = 10 −5 , Greenhouse-Geisser corrected), and a significant interaction was found between these two factors ( F (3,15) = 85.102, p = 10 −8 ).
In a set of ubiquitously expressed housekeeping genes ( n =374), a highly significant positive correlation between expression and the mutational bias (B) (r=0.28; P <10−7) was reported 24 .
3 Discussion The first significant finding derived from this study is the clear and highly significant correlation between TD and response, with a response rate of only 9.1% for patients with TD <205 Gy against 89.7% for those with TD ≥205 Gy, P <10 −7 .
Ethnic Affiliation Related Pattern distributions differences in the various ethnic groups, which returned highly significant differences between the groups at the 5% level (χ 2 , p<0.0000001), have revealed that the Nilo-Saharan Berta manifested significantly higher Arch frequencies (18.68%), which is high both with respect to the other studied local ethnic groups (having arch frequencies less than 7%), as well as relative to other studied populations worldwide [ 3 , 4 ].
Further analysis of the gene set revealed a highly significant enrichment (p= 1.0 −7 ) for the upstream regulator hepatocyte nuclear factor 4 alpha (HNF4α), which regulates almost 200 genes (~ 15% of genes) in the list of differentially expressed genes between the two groups post-treatment ( Supplementary Table 1B ).
The final model (Predation = −66.2917 + 2.15625G − 0.8421X + 0.0106X 2 ) was highly significant (F 3,47 = 323.8478, p = 1 × 10 −7 ) and explained a large proportion of variation in predation (adjusted R 2 = 0.9537).
Only SNPs mapped to autosomes with CR > 0.98, minor allele frequencies (MAF) > 0.03, and not in highly significant deviation Hardy–Weinberg equilibrium (P > 10 −7 ) were considered in the analyses.
The correlation between fluorescence and bone vitality was highly significant ( p < 0.0000001).
The two features were highly significant by hypothesis testing of difference between type medians ( p < 10 −7 and p < 10 −6 , respectively; Figure 4D ), and to a lesser extent by testing of correlation with age ( p < 10 −4 and p < 10 −3 ) or body mass index ( p < 10 −2 and p < 5 × 10 −2 ).
Regarding the favorability hypothesis, the combined effect of political climate was highly significant when the covariates were controlled ( Z = 6.68, p <.0000001) and when the covariates were not controlled ( Z = 6.45, p <.0000001).
As shown in Figure 4 A, a one-way ANOVA with 10 levels of Dream-Age (1–10 years) as independent variable and current (log) nightmare recall as dependent variable revealed a highly significant main effect ( F 9,17004 = 6.08, p < 0.0000001) showing that earlier recalled dreams were associated with frequent current nightmares.
ANCOVA with post-intervention VASs as the dependent variable and baseline VASa as covariate showed that the group effect remained highly significant after adjustment (F = 40.36, p < 1 × 10 −7 , η 2 = 0.25), confirming that the intervention effect is not explained by baseline differences the same applied for VASs (F(1,46) = 22.45, p = 2.1 × 10 −5 , η 2 = 0.12).
Comparison of the cross‐sectional area of stems produced by the same plant in 2000 and in 2001 showed a highly significant effect of treatment ( F 1, 168 = 31.10, p < .0000001).
4 confirm that the association between folding intermediates and translational pause sites is highly significant (one-sided P < 10 − 7 at neutral-model P -value thresholds below 0.01; SI Appendix , Fig.
We found that for both RT and confidence, the fixed effect of conflict was highly significant across all levels of complexity (all p <.0000001).
Of the 45 pairwise differences between the modules, 32 were significant ( p < 0.05, of which 24 were highly significant, p < 1.00 × 10 − 7 ) and 13 were not ( p > 0.05).
Pearson correlations revealed low, but highly significant, positive correlations between DRF and DTD for the entire sample ( r 28888 = 0.282; p < 0.0000001) and for males ( r 5884 = 0.276; p < 0.0000001) and females ( r 23004 = 0.287; p < 0.0000001) considered separately.
While the p values for both the clinical TNM and the proposed TB model’s staging, for the aforementioned statistical tests, are highly significant (p < 1E-07), the proposed staging yields larger test statistics.
flexneri was very highly significant ( P < 0.0000001), but survival of alone-cultivated A. castellanii compared to that of cocultivated with plasmid-cured S. flexneri was not statistically significant ( P = 0.88).
The coefficient for study arm was −12 (SEM 4.1), and the inclusion of study arm to the model was highly significant ( P = 10 −7 ), demonstrating a strong influence of the intervention on salt intake.
We found very strong evidence of association of multiple SNPs at TTC12 and ANKK1 in two different populations, EAs and AAs (minimal P=0.0007 in AAs and minimal P=0.00009 in EAs), and highly significant association of a single haplotype (set of markers) spanning TTC12 and ANKK1 to ND in the pooled sample (P=0. 0000001).
The test showed highly significant correlations for all four locations (C6‐r: tau = 0.52, p < 10 −7 ; C6‐l: tau = 0.52, p < 10 −7 ; C5‐r: tau = 0.53, p < 10 −7 ; C5‐l: tau = 0.50, p < 10 −6 ), confirming a statistically significant increase in the diameter with age for all four locations.