This analysis showed a lower 12-month mortality rate for the early surgery cohort; however, this did not quite reach statistical significance (possibly due to lack of power).
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The decline of 10% in the faculty of law did not quite reach statistical significance, but the CI for the difference between the surveys was still compatible with a decline more than with no decline.
In line, the same trend was observed for IHC‐based protein expression of the seven markers in the validation cohort, although it did not quite reach statistical significance when tested as a negative survival predictor (HR (high) = 2.68 [0.88–8.14], P (HR) = 0.082) (Fig.
A similar trend was observed with NOTCH3 that did not quite reach statistical significance ( Figure 3 C).
Although this association did not quite reach statistical significance, our results support previous findings that have shown vitamin A to influence host response to influenza virus infection [ 43 ].
Several other polymorphisms showed quite a strong trend of association with extracolonic manifestations but these did not quite reach statistical significance ( Supplementary Table S3 ).
We detected a trend towards an increase in the number of granule neurons in Smad3 deficient mice (23.8%) compared with their control littermates (first 500 μm; Smad3 +/+ , 40986 ± 3406; Smad3 -/- , 50797 ± 2823; P = 0.059; Figure 4 F), although this strong trend did not quite reach statistical significance.
Table 2 shows that the ASD sample used fewer emotion words overall than the NT group, though this difference did not quite reach statistical significance and the effect size was small.
Consistent with the UCSF results, when all three NFκB and AP-1 upregulated genes were combined to produce four subsets within each dataset, the resulting Kaplan-Meier curves showed a rank order correlation between increasingly worse outcome and number of high expressing genes (HHH > HHL > HLL > LLL); although these outcome differences did not quite reach statistical significance by Log Rank analysis, in each dataset those cases showing high expression of all three NFκB and AP-1 upregulated genes (HHH) exhibited median times to metastatic recurrence ≤ 5 years (data not shown).
However, results did not quite reach statistical significance on the test set.
Several prior studies have associated bipolar disorder with altered concentrations of IL-1 receptor antagonist [ 18 , 35 , 43 , 44 ] and IL-6 [ 33 – 35 ], which in our results did not quite reach statistical significance in both cohorts when controlling for relevant covariates.
Notably, similar proportions of past 12-month cannabis use were found for those who never deployed and those who deployed without DRTEs, but a higher proportion for those who deployed with DRTEs although this OR did not quite reach statistical significance.
The change in waist circumference did not quite reach statistical significance.
Although increases in NHE activity were observed at all concentrations of ET-1 tested, with a greater than 2-fold increase in NHE activity at 10 nmol/L, the difference with 0.1 nmol/L ET-1 did not quite reach statistical significance.
This increase did not quite reach statistical significance but statistically significant increases in ubiquitination of liprin-α1 were observed in immunoprecipitates from cells transfected with the neuronal LNX1p70 isoform ( p < 0.05), which lacks the RING finger domain required for ubiquitination, and LNX2 ( p < 0.05), compared to the control vector ( Fig 3B , upper graph).
Similarly, a 2-fold decrease was seen for the numbers of esophageal CD8+ T cells/mm 2 among the responders, although this did not quite reach statistical significance, and the CD8+ T-cell numbers remained unchanged among the non-responders post-treatment ( Fig. 2B ).
The same trend was observed for both CD20 and CD68 infiltration, though these did not quite reach statistical significance (Figure 5E ).
In addition, 16‐month‐old WT mice had a tendency to have a higher SREBP1 mRNA level than younger counterparts, but this did not quite reach statistical significance.
29 Jia et al demonstrated a slightly higher recurrence risk for EAEBOTs, which, however, did not quite reach statistical significance. 1 But, to further evaluate possible differences between EAEBOTs and non-EAEBOTs, studies with large sample sizes are needed.
TMR/PRP patients had an increased mean EF compared to CABG alone (57.8% vs 54.1%, p = 0.24, Figure 5 ), though this did not quite reach statistical significance.
Although this did not quite reach statistical significance, this most likely reflects the limited number of non-failing samples in our study.
Although the Charnley stem is considered the more historic method of hip arthroplasty, we have demonstrated equal performance of the Charnley stem when we compared it to the use of the Exeter stem, with better performance across areas such as WOMAC score which did not quite reach statistical significance.
Among those who were unemployed, the two older groups were less likely to report unmet needs than the youngest group, but the results did not quite reach statistical significance.
For CO, we observed a trend across tertiles of exposure (1st tertile, 5.1%; 2nd tertile, 7.7%; 3rd tertile, 21.1%; p = 0.03) ( Table 4 ) and an increase in the odds of diagnosing FTV [adjusted odds ratio (aOR) = 2.5, 95% CI: 1.0, 6.4] with increasing ln-transformed CO exposure after covariate adjustment, although the latter did not quite reach statistical significance in adjusted or unadjusted models (see Table S2).
Considering all participants in whom 8‐oxo‐dG measurements were made ( n = 75), there was only a significant univariate relationship between 8‐oxo‐dG levels and BMI (standardized β 0.32, P = 0.005); although there were trends towards an association between 8‐oxo‐dG levels with FFMI ( P = 0.06), RV/TLC ( P = 0.08), and serum GDF‐15 ( P = 0.06), these relationships did not quite reach statistical significance.