“borderline significant”

Although the association with ISUP grade was only borderline significant (r = –0.239, p = 0.053), the trend suggests a possible link with tumor aggressiveness that warrants further investigation in larger cohorts.

Mutation profiles of 578 cancer-relevant genes Numbers of mutations Somatic mutational analysis identified an average of 174 non-synonymous somatic mutations per Mb in dMMR LS-BCs, compared with 33/Mb in pMMR LS-BCs (non-significant difference) and 88/Mb in NC-BCs (borderline significant relative to dMMR LS-BC, p = 0.053) ( Table 2 ).

Serological evidence of prior infection with HSV‐1 was also associated with modestly increased odds of developing MS (OR: 1.54, 95% CI: 1.06–2.25, P ‐value = 0.025), while for the association with HSV‐2 was only borderline significant (OR: 1.54, 95% CI: 1.00–2.38, P ‐value = 0.053).

Of the observed differences, those between SLIM + BA and SLIM + OM reached statistical significance for T2D (adjusted p = 4.05E − 6) and were borderline significant for obesity-related cancer (adjusted p = 0.053) after correction for multiple testing.

Night-time declamping was associated with worse 1-year post-transplant patient and graft survival before (HR = 1.44(0.99–2.1); p = 0.058) and borderline significant after adjustment for other predictors (HR= 1.49 (0.99–2.22); p = 0.053), findings which were consistent with the analysis of the entire cohort. 4.

There was a dose‐dependent increase of pericardial effusion (Table 2 ), whereas there was a numerically modest, borderline significant increase in T2 ratio ( P =0.053).

NB displayed borderline significant 17q gain enrichment ( p = 0.053 by Fisher's exact test) (Figure S12 ).

[ 43 ] developed a CT-based radiomic model with an AUC of 0.61 and borderline significant Kaplan–Meier curve result in the validation dataset ( p = 0.053).

High PD-1 expression was significantly associated with a prolonged OS in gastric cancer ( p = 0.041), whereas a borderline significant association was observed between high PD-1 expression and a shorter OS ( p = 0.053) in esophageal cancer.

Compared to the untreated mgR/mgR Marfan aorta that did not have contact with adenovirus, the NI was significantly larger in Ad.hTIMP-1-treated (p<0.001) and borderline significant in Ad.β-Gal-treated mgR/mgR aorta (p = 0.053).

There was a borderline significant correlation of the degree of trunk flexion with age (ρ = 0.334; p = 0.053), but with none of the other demographics and disease characteristics. 3.2.

GHQ scores showed a borderline significant difference, with lost patients having numerically higher scores (median 8 vs. 6, p = 0.053).

There was a borderline significant difference in incidence of AGI between participants with blue collar jobs and with white collar jobs (0.28 vs 0.45 p = 0.053).

PA and PROMs in Cross-Sectional Analysis At baseline, patients performing high PA reported fewer occurrences of liquid/soft stools compared to those with low PA, with a borderline significant difference (median 0 [0–1] vs. 0 [0–2], p = 0.053).

We detected a borderline significant difference ( p = 0.053) in the expression of KIR2DL1 and KIR2DP1 among males with CVD (data not shown).

Among participants with elevated SIRI levels, a high OBS exhibited a borderline significant association with reduced mortality (HR = 0.59, 95% CI 0.34–1.01, P = .053).

The 14% difference in C-max between placebo and FDJ was significant ( p = 0.001), whereas the 6% difference between placebo and FD was borderline significant ( p = 0.053).

Free vaccination showed a borderline significant association with higher vaccination uptake rates in the elderly (correlation coefficient 0.43, p = 0.053).

There were no significant differences in ECG characteristics between the two groups, although there was a borderline significant association between presence of pathologic Q waves in patients with elevated cTnT vs. patients with normal cTnT (26% vs. 7%, P = 0.053).

Within-group longitudinal analyses across 2 time points (by the Wilcoxon signed-rank test) confirmed stable over time TNF-α levels in the evolocumab group (all p > 0.1), whereas in the control group a borderline significant increase was observed at 72 h vs. baseline ( p = 0.053) ( Supplementary Table S2 ).

The effect of condition was borderline significant ( F [1,11] = 4.72, η 2 = 0.30, p = 0.053), whereas the interaction between timing and condition did not reach significance ( F [1,11] = 3.70, η 2 = 0.25, p = 0.081).

After adjusting for the period effect, the difference in Stiffness Index between baseline and 2 h in the LFD and TP + FM arm remained borderline significant ( p = 0.053), as well as the difference between baseline and 3.5 h in the LFD-only + FM group ( p = 0.02).

Among HER2 positive patients, exploratory analysis of the NeoALTTO trial have demonstrated a borderline significant decreased pCR rate for overweight/obese patients with HR + /HER2+ breast cancer (OR = 0.55, P = 0.053), but not in HR-/HER2+ breast cancer (OR = 1.3, P = 0.331) 11 .

The GRS of lncRNAs was significantly associated with AL progression between 6 and 9 years, 9–13 years and AL/CR at 13 years and borderline significant with RE (FDR adjusted P = 0.053).

The difference was borderline significant between two groups ( P = 0.053).