However, it must be noted that in our meta-analysis the latter study was borderline significant ( p = 0.05).
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The multivariate analysis confirmed the effect of EGFR mutation and advanced nodal stage, which were strongly associated with brain metastases development, while age was borderline significant (p = 0.05).
A borderline significant difference in survival was observed for patients with localised cancer stage ( p = 0.05).
The difference for the 3 rd PDM gain of the ABP input was borderline significant ( p = 0.050), inviting some thoughts about its mechanism of origin (see Discussion). 4 Discussion The regulation of cerebral blood flow is achieved through intricate coordination of multiple homeostatic mechanisms driven by mechanical signaling (e.g., blood pressure variations) and/or chemical signaling (e.g., blood gas variations) occurring systemically throughout the cerebrovascular and autonomic nexus ( Willie et al., 2014 ).
Subgroup analysis indicated a borderline significant benefit for the FMR+ablative fractional laser (AFL) combination (OR: 2.76, 95% CI: 0.99-7.71, p=0.05) but not for FMR+non-ablative fractional laser (NAFL).
In chronic patients (7 trials, N = 194), the MD was 2.20 points (95% CI -0.01 to 4.40), an effect that was borderline significant ( p = 0.05), with no heterogeneity (I2 = 0%).
ITT Eradication Rates Meta‐analysis of 8 trials (2502 patients: 1318 tailored; 1184 concomitant) showed a borderline significant difference favoring tailored therapy (RR = 1.05; 95% CI: 1.00–1.10; p = 0.05; I 2 = 58%) (Figure 2 ).
At TP2, with less data available, we observed only a borderline significant difference with worse OS in patients with FCM-MRD ≥ 0.01% ( p = 0.050; Supplementary Figure 6 ).
While mortality between the cohorts remained unchanged, the combined stroke/TIA risk converged with the passage of time: at 2 years, the risk was borderline significant (11.2% vs. 6.5%, p = 0.05) [ 16 ], and at 5 years the risk was equivalent between the groups (15.9% vs. 14.7%, p = 0.35) [ 17 ].
Moreover, in a prospective randomized, double-blind, placebo-controlled trial enrolling 106 patients with both NAFLD and T2DM who were assigned to receive empagliflozin 10 mg ( n = 35), pioglitazone 30 mg ( n = 34), or placebo ( n = 37) for 24 weeks, only a borderline significant decrease in CAP score was observed with empagliflozin compared with placebo (−29.6 dB/m (−39.5 to −19.6) vs. −16.4 dB/m (−25.0 to −7.8), respectively; p = 0.05) [ 39 ].
However, educational level was found to be borderline significant ( p = 0.05).
The LRT of S3 exhibited a borderline significant increase (p = 0.05) in comparison to that of age and BMI.
Notably, the direct causal effect of PE on FEV1 was borderline significant (OR 0.921, 95% CI 0.848–1.000, P = 0.050), which was inconsistent with UVMR and should be interpreted with caution (Table 3 ).
In addition, while the AUC of DNI in patients with USG abnormalities was borderline significant ( P = 0.05) it was nearly comparable to that of CRP, both of which being much more significant than either the WBC count and ESR.
This study found that patients with CeD, younger-onset diabetes, MS, asthma, and SLE were at higher risk of ALS, and the rate ratio for UC was borderline significant ( P = 0.05), and no significant difference was found for RA, psoriasis and CD.
Secondary analyses to examine the dose–response relationship between cognitive function and IL-6 showed MoCA quintiles to be a borderline significant predictor of cortisol AUC responses after surgery ( β = −0.176, CI = −906.318–−0.370, p = 0.050) after controlling for covariates.
A borderline significant difference was observed among subgroups ( p = 0.05) ( Figure 6 ). 3.4.3.
Chehrehgosha et al [ 20 ] reported a marked within-group CAP reduction with empagliflozin (317.37 ± 28.46 to 287.80 ± 31.14 dB/m), though the between-group difference versus placebo was borderline significant (−29.6 vs. −16.4 dB/m, P = 0.05).
When grouped by the number of medications patients were on at the 20-year mark, there was a borderline significant difference between the groups on 0-1 (n=61), 2-4 (n=46) and ≥5 (n=39) different medications (10-year OS 93%, 93% and 76% respectively, p=0.05).
There was no significant difference between CD8 memory T-cell subsets ( Figure S3A ); however, for CD4 memory a significant lower level of Tem (CD45RA-CCR7-, p=0.02), and a borderline significant higher level of naïve (CD45RA+CCR7+, p=0.05) T-cells was detected in MACDZ compared to IGRA-HC ( Figure 2B ).
No other statistically significant differences in median WB Cr and WB Co levels were observed in relation to grade of atrophy in other muscle groups (all p > 0.05). There was a borderline significant (p = 0.05) but relatively small difference in the distribution of grade of atrophy in g. maximus across different PT findings ( Figure 4 ).
In a Cox-proportional hazard model where the cause-specific hazards were investigated ( Figure 1B ), eGFR was only borderline significant ( P = .05) for CV events.
VAS-based appetite ratings did not show significant changes in hunger, fullness, or desire to eat, but a borderline significant reduction was observed in prospective food consumption after pelemir-enriched bread ( p = 0.050).
However, there were significant differences ( p < 0.05) in age, education, and years of experience (work tenure), and a borderline significant difference in gender between groups ( p = 0.050).
A borderline significant ( p = 0.05) finding was that Medicaid patients had poorer overall survival compared to uninsured patients (HR = 1.14, p = 0.05).