Generally, consistent results were observed when assessing HF (921 cases in Table S2 ) and ASCVD (517 cases in Table S3 ) separately, although a borderline significant interaction was observed between hemoglobin status and ACR for ASCVD, where the association of high ACR with risk of ASCVD tended to be stronger among those with high hemoglobin compared with normal hemoglobin or anemia ( P ‐for‐interaction, 0.074; Table S3 ).
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The inverse of that was found in the present study with a borderline significant increase in PDCD1LG2 [PD-L2] between st-FL and nt-FL samples, as well as an even further increase in tFL samples.
No such significant or borderline significant correlations were found when studying the relationship to LBM (investigations in females and males made separately). 4 Discussion The study led to several observations of which three appeared of physiologic and practical importance.
Women with intermediate and intensive physical activity at work had an increased risk for KR compared to those with a sedentary activity level, whereas the risk in women with moderate physical activity was borderline significant (Table 4 ).
Therefore, it is imaginable that borderline significant difference would not be significant if the postoperative CT scan was added.
However, 1 study 34 detected only a borderline significant change in effect of the intervention on children's self‐efficacy related to barriers for PA.
For the serious mental illness outcome, the CI (0.47-0.97) is borderline significant, reflecting limited statistical precision due to the smaller number of events (n = 67) relative to the number of predictors, resulting in approximately seven events per predictor, below the commonly recommended guideline of 10 events per predictor.
ELISA confirmed a borderline significant rise in beta‐2‐microglobulin within two years of diagnosis in EPIC.
Moreover, the inverse association between food itching and urticaria (AOR: 0.54, 95% CI: 0.29-1.02), matter itching and urticaria (AOR: 0.54, 95% CI: 0.28-1.03), allergy to pets (AOR: 0.44, 95% CI: 0.18-1.05), seasonal cruise (AOR: 0.40, 95% CI: 0.21-0.76), and childhood colds (AOR: 0.56, 95% CI: 0.33-0.97) were borderline significant in multiple logistic regression.
For the VDR gene, the haplotype A-T-G in LD block 1 (rs11574143-TaqI-BsmI), which contained the borderline significant BsmI risk G allele from previous single SNP analysis, was associated with a reduced OS of rectal cancer in comparison to the most common haplotype (HR, 2.53; 95% CI, 1.20–5.34; block global P =0.027), although this association was no longer significant when Bonferroni’s correction was applied.
The trial showed a statistically significant decrease in the risk of hospitalization with an absolute risk reduction (ARR) of 11.7%, a borderline significant reduction in oxygen supplementation, a non-significant decrease in all causes of mortality, and no indication of harm associated with the treatment.
The likelihood ratio test revealed that hypertension and CHD may be potential effect modifiers for the FHR-mortality association, with borderline significant interaction effects ( Table 3 ; P -interaction for hypertension = 0.07, P -interaction for CHD = 0.08).
In a French nationwide healthcare database sample of 3853 breast cancer patients, radiotherapy-treated patients had 28 permanent pacemaker implantations compared with 13 expected cases, corresponding to a standardized incidence ratio of 2.18, although the direct comparison with non-irradiated breast cancer patients was only borderline significant [ 193 ].
Most users (75%) reported using non-flavored tobacco and had a borderline significant association with the risk of bladder cancer (OR = 1.62; 95% CI, 0.99–2.65).
Compared to the MHNAO reference group, the metabolically healthy abdominal obese (MHAO) phenotype was associated with a significantly enhanced risk of diabetes in women (adjusted HR 1.68, 95% CI 1.08 – 2.6) and a borderline significant increase in men (adjusted HR 1.5, 95% CI 1.0 – 2.36).
Highest (sex-specific) quartile of physical activity was associated with 14% lower risk (OR=0.86, 95% CI 0.77 to 0.95) of visual impairment than those in the bottom quartile group, although the linear relationship between the two was only borderline significant.
Also, when analysing the latitude, after the inclusion of 10 PCs, the slope is only borderline significant.
Anything above p = 0.003 but below p = 0.05 was considered borderline significant.
Furthermore, the dynamic study design led to variation in follow-up across participants, and although linear mixed-effects models were used to address missing data and confounding, the lack of correction for multiple comparisons raises the possibility of Type I errors, meaning some borderline significant findings should be viewed as exploratory and require confirmation in larger studies.
While overexpression of Cdkn1a and Pde7b resulted in increased glucagon release at 1 mM glucose compared to control transfected α-cells, Sept9 overexpression led to a borderline significant increase in glucagon secretion ( Figure S3D and Figure 4L ).
Borderline significant correlations were observed between years of specialization in pediatrics of the referents and the overall scores assigned in the items of “editorial independence” domain (r = 0.535; p = 0.09), and between the overall quality scores assigned to all CGs and the number of control visits carried out by each participating center in 2012 (r = 0.503; p = 0.11).
For the two studies that included both the total phenol content of the olive oil and hypertensive participants, an EVOO with a total phenol of 161 mg/kg [ 48 ] and one with 564 mg/kg [ 63 ] both lowered SBP, while DBP was lowered only with the 564 mg/kg total phenol olive oil and was borderline significant for the 161 mg/kg total phenols.
These two factors level the results between patients and controls and explain why their results were only borderline significant.
While no significant associations were found between GFAP or NfL levels and cognitive outcomes overall, in the SRC group, moderate GFAP levels at 26 weeks showed a borderline significant link to slower identification task (latency), while extreme and minimally elevated NfL levels at 26 weeks were significantly associated with slower identification task (latency), but moderate NfL levels were not. 104 The lack of consistent associations with moderate NfL levels suggests that this relationship may vary.
We observed that MAS98.12 xenografts display a borderline significant higher expression of MYC than MAS98.06 xenografts.