Barely Significant
← all phrases

“borderline significant”

11,410 sentences · 11,410 papers · 14,072 search hits before verification · confirmed specimen

Sighted at

p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Studies on refined grain consumption have been less consistent and have in general shown no clear association 14 , 15 , 17 , 18 , 20 , 23 , however, a Chinese study reported an inverse association between intake of rice and risk of hypertension 23 , and another study reported a borderline significant inverse association with refined grains 17 and two other studies reported non-significant inverse associations 14 , 20 , but may have been underpowered to detect a clear association.
42 , 61 , 71 , 77 , 79 , 80 It was associated with higher risk of coronary heart disease, 80 heart failure, 77 myocardial infarction, 61 , 79 cardiomyopathy, 42 stroke (borderline significant), 80 and stroke mortality. 71 Of the 3 reviews that assessed the association between income and composite CVD mortality, 2 reported existence of association, 61 , 80 and the other one 76 found no association.
When comparing the two-year overall progression in our placebo group and 0.01% (0.57 mm and 0.47 mm, respectively), it translates to a moderate treatment effect of an 18% reduction in AL progression in the 0.01% group compared to placebo, which is clinically relevant and is in line with the borderline significant one-year treatment effect we found in the 0.01% group in our previous interim analysis [ 24 ].
A site-specific analysis showed that after this date there were significant reductions of 73% for fatal cancers of the respiratory and intrathoracic organs; 78% for lymphatic and haemopoetic cancer, 49% for genitourinary cancers, and a borderline significant reduction of 39% for digestive and peritoneal cancers.