“borderline significant”

(I) Stromal score shows a borderline significant difference between high-risk and low-risk melanoma patients; Table S1: correlation analysis between SIT1 and markers of immune cells in SKCM of TIMER and GEPIA; Table S2: functions of the genes included in the prognostic signatures; Table S3: comparison of clinicopathological features between the low- and high-risk subgroups of the TCGA_SKCM dataset; Table S4: comparison of clinicopathological features between the low- and high-risk subgroups of the GSE69540 dataset.

Additionally, 4 genes exhibited borderline significant upregulation (fold change 1.8–2.0), such as Mx1 (1.95), Nfkbia (1.95), Tnf (1.94), and Stat3 (1.92), as shown in Table 2 .

Although the estimate size remains borderline significant, we observed a tendency showing a greater increase in HDL-C to have a more significant reduction of CAD risk (Table 4 ).

A borderline significant inverse association was found for pRCC per kg/m 2 increase (HR 0.91, 95% CI 0.82‐1.00).

Of note, due to the low number of primitive samples in the Oslo cohort, borderline significant microRNAs for tests with this subtype were included if significant in the LUSC cohort.

However, the effect becomes borderline significant when working with the top 50% objects and insignificant when working with 100% objects, probably because of the smaller number of keywords in those objects.

Interactions between aspirin/NSAIDs with TXNRD1 rs4964778 remained statistically significant for colon cancer after adjustment for multiple comparison; rs17745445 of TNXRD2 was borderline significant after adjustment for multiple comparison with the step-down Bonferroni correction.

In men, living alone was associated with a 59% higher odds of pre-diabetes (borderline significant), a 84% higher odds of newly diagnosed T2DM (borderline significant), and a 94% higher odds of previously diagnosed T2DM compared to NGM (Table 3 ).

Meanwhile, the visceral fat area of patients with excessive weight gain was also higher, which was borderline significant at baseline, and became significant at the euthyroid stage.

After adjusting for gender, age, BMI, smoking, job strain and usual level of leisure time physical activity, the relation between ambulatory BP and lifting heavy loads at work remained significant, while the association with the summary measure of occupational physical activity became borderline significant.

STIM1 also showed a modest borderline significant correlation with the vascular invasion status (OR = 1.4474, 95% CI = 0.99~2.15), but a significant threshold was not reached ( p = 0.0593).

However, there was a borderline significant effect for perinatal mortality in the first 2 pregnancies (RR = 0.73, 95% CI: 0.53–0.99).

Conclusion We found a correlation between the thickness of the choroid and the HRV-measured LF/HF ratio in patients with CSC and showed a borderline significant reduction in HRV measurements in patients with CSC.

Since a borderline significant correlation was detected in the MDD group, our speculation is that the relative small sample size may limit our ability to detect the statistical significance in current study.

36 The results from observational studies were inconsistent 41 ; however, the pooled estimate from a meta-analysis showed only a borderline significant reduction in hospital admission with metformin (odds ratio 0.73, 95% CI 0.53 to 1.00). 15 Similar to the findings from our systematic review, a meta-analysis of four observational studies with 1646 patients did not find any significant difference in hospital stay (mean difference 1.07, 95% CI −0.55 to 2.69). 12 Metformin's anti-inflammatory capabilities and function in modifying the immune response could explain the reported reduction in long covid.

At the eight-month follow-up, the between-group difference remained significant (mean difference of 4.59 points) on the MCS, whereas that on the CBS was borderline significant (mean change of −0.14 points).

We observed a borderline significant change in mean BF, although median values remained unchanged between light-off and light-on conditions (light-off median: 9.51 kHz, light-on median: 9.51 kHz; light-off mean: 7.61 kHz, light-on mean: 7.81 kHz; signed-rank test, P = 0.047; Fig. 4 C ).

However, conservatively treated patients reported fewer arm problems and a borderline significant benefit in body image.

In addition, there was no significant change in the lumbar bending total range of motion (ROM) in any exercise group, even though improvements in this parameter with 5.3% from 47.0° to 49.5° ( p = 0.053) and the 6 MWT with 3.4% from 553 m to 572 m ( p = 0.061;) were borderline significant in the QG group, see also Table 2 .

There was no significant effect of PFASs on immunity in youths but a significant effect of both PFOA and PFOS in adults, as well as a significant interaction of PFOA x sex and a borderline significant interaction of PFOS x sex.

2 , 3 In a study by Demissei et al, 2 high-sensitivity cTnT (hs-cTnT) greater than the upper reference limit at the end of anthracycline therapy had a borderline significant association with risk for CTRCD within 1 year after the completion of anthracycline therapy.

Overall, there was a borderline significant reduction in the primary end point of days lost to death or cardiovascular hospitalisation from 6.6% in the usual-care group to 4.9% in the RPM group (ratio 0.80, 95% confidence interval [CI] 0.65-1.00; P = 0.046) but no significant difference in mortality.

The association was borderline significant after adjusted for age, current smoking, alcohol consumption, hypertension, diabetes, BMI, high- sensitive CRP and LDL-cholesterol (OR = 2.25, 95% CI:0.97–5.24, p = 0.06).

One methodologic limitation was that this study did not adjust for multiple comparisons; therefore, borderline significant findings should be approached with caution, though in our dataset most gender differences were strongly significant.

Further analysis revealed borderline significant interactions of age with race/ethnicity and race/ethnicity with religion raised.