“borderline significant”

For the seed-based analyses, all results also remained significant or borderline significant, with the exception of the reduced connectivity between mPFC and insula (see Supplementary Data ).

found a borderline significant association between CIZ integrity and changes in postoperative vision [ 21 , 22 ].

An important novel finding from our data is that REG-family gene expression is significantly elevated in Fusobacterium-H CRCs with dramatic fold change increases detected; this includes REG1A , REG3A and REG1P , as well as a borderline significant expression for REG1B (FC = 12.2, FDR = 0.17).

Other cytokines/chemokines that showed a borderline significant increase in acute dengue compared with healthy ones were IP-10, MIP-1 β , and IL-7 ( Figure 3(c) ).

The countries that had BCG vaccination coverage had a statistically borderline significant less daily mortality count as compared with countries without BCG coverage in the national immunization program (IRR 0.43, 95% CI 0.19 to 1.00).

Although difficulty in emotion regulation did not have a statistically significant effect on family accommodation, it showed a borderline significant effect.

Specific organ system events also trended upward, including all-grade pneumonia (significantly higher), grade ≥ 3 neutropenia (borderline significant), all-grade thrombocytopenia and anemia (both non-significant overall, but all-grade anemia became significant after CHECKMATE-602 removal), and grade ≥ 3 rash (significantly higher); in contrast, diarrhea rates were unaffected.

Medians were slightly higher in informal urban areas, although only a borderline significant difference was found for women (Table 2 ).

Post hoc analyses for level of fatigue showed beneficial effects of exercise for the highly fatigued patients, on Wordlist Learning (B4.36, 95% CI 0.47; 8.25) and Reaction Time (B-26.7, 95% CI − 52.9; − 0.6), and a borderline significant improvement on Wordlist Recognition (B0.96, 95% CI − 0.06; 1.98) (Fig. 3 and Additional file 1 : Table S6).

BMI was borderline significant in the univariable model, and sex was not associated with attrition ( table 3 ).

Structural similarity searches of D1, conducted using the DALI, yielded borderline significant alignments (z-score less than 5.6).

ASM/Ht 2 showed borderline significant correlations with VFT and SFT.

In crude analyses the risk of disability pension was elevated, the association did however only remain borderline significant when adjusting for other malformations, and was just short of remaining significant when birth weight and gestational age was added to the model (adjusted OR 1.20, 95% CI 0.98–1.48).

Use of surfactant was associated with a non-significant decrease in duration of mechanical ventilation by 2.6 days and a borderline significant decrease in ICU length of stay by 3.3 days.

Interestingly, in the control treatment group a borderline significant increases of BP values were observed, leading to the difference in change of SBP of 11.1 mmHg (95% CI 6.5–15.8) and DBP of 8.3 mmHg (95% CI 3.98–12.6) between CPT and IPT groups ( Figure 2 A and B ).

Conversely, p -values for precision (0.333) suggest no statistically significant differences in this metric, reflecting similar performance among the classifiers and borderline significant differences for the F1 score (0.054).

In all tests, p-values were considered statistically significant if ≤ 0.05, except when studying interactions with gender in which p-values ≤ 0.10 were considered borderline significant and yield reporting of gender specific associations.

It showed a borderline significant association with TC in the Polish population. 6 rs1867277 was studied because it lies in the 5′ UTR of FOXE1 (or Thyroid Transcription Factor 2 ), a key gene involved in thyroid organogenesis. 7 rs1867277 and rs965513 are in moderate pairwise linkage disequilibrium (LD) in Europeans ( r 2 =0.39, D '=0.73, http://www.1000genomes.org/ ). rs1867277 was strongly associated with TC risk in Spanish and Italian cohorts. 5 None of the three candidate SNP associations has been replicated in independent studies.

Intriguingly, in a sensitivity analysis where we dropped seed participants and applied RDS-II weighting, we found a borderline significant impact of the programme aligned with the 40% reduction hypothesised.

A small, borderline significant effect of the BMI variable on the participants’ levels of adherence to the MD was observed.

A large prospective study with 409,885 participants from nine European countries (European Prospective Investigation Into Cancer and Nutrition) reports that although there is no clear association between the consumption of white fish or fatty fish and IHD risk, a borderline significant inverse association is observed in the substitution analyses [ 96 ].

In the Mickenautsh 2016 publication, the authors, based on 2 CTs, showed a borderline significant reduced probability of caries incidence when using high-viscosity GI compared to resin-based FS after 60 months of follow-up RR = 0.29 [95%CI: (0.09–0.95)].

Meta-analysis results PCa For cohort studies, the risk of PCa in patients with IBD were of borderline significant increase (SIR: 1.09; 95% CI: 0.95–1.22; I 2 =61.2%; Figure 2 ) when compared with the background population, as was the risk of subgroup of UC (SIR: 1.13; 95% CI: 0.93–1.33; I 2 =73.5%; Figure 2 ) and CD (SIR: 1.05; 95% CI: 0.90–1.21; I 2 =15.1%; Figure 2 ).

Also, rural municipalities showed a risk for cardiovascular diseases death 2.2% higher than urban or peri-urban ones, but in this case, the association was borderline significant (PP = 0.937).

Because the sample size was relatively small, the association only reached borderline significant (CG vs.