The results of the RCT carried on by Nadaraja and colleagues on 96 patients shown oncologic treatment allocation for frail older cancer patients based on G8 screening followed by CGA had no impact on treatment completion, OS or median progression-free survival (PFS) but resulted in a borderline significant lower incidence of grade III to IV toxicity in the intervention group compared with the control group [ 69 ].
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Discussion Our meta-analysis yielded borderline significant RRs of 1.3 and 1.4 between glyphosate use and risk of NHL and MM, respectively, and no significant association with risk of HL or leukemia.
No significant associations were observed for mushrooms (OR = 1.09; 95% CI: 0.94–1.27) and tea consumption shows a borderline significant association (OR = 1.13; 95% CI: 1.00–1.28).
When considering the variants burden and the risk of developing severe fluoropyrimidine toxicity ( Table 3 A), a borderline significant association was observed for very rare variants (including novel ones).
The Mini-Mental State Examination or similar test aimed to assess cognitive capacity were administered in the inclusion stage in 41 (51.2%) publications, namely in 3 (23.1%), 18 (64.3%), and 20 (51.3%) studies in year 2004, 2009, and 2014, respectively; this difference across the three years was borderline significant but had no linear-by-linear association (Table 3 ).
The association with anxiety disorder was borderline significant (OR 2.78; 95% CI 1.00 to 7.74).
PD-L1 expression was a strong indicator for worse overall survival (OS) but borderline significant in disease-free survival (DFS).
Although the coefficient for this expenditure is not statistically significant in this subsample, it is borderline significant in the full sample.
We found a positive association between red meat intake specifically and cancers of the esophagus and liver, and a borderline significant positive association for laryngeal cancer.
DISCUSSION Out of the 13 cytokine-related polymorphisms that were studied for susceptibility to or progression of CCC, only BAT1 −22 C>G (rs3853601) and IFNG +874 T>A (rs2430561) remained borderline significant for protection in the logistic regression analysis with adjustment for non-genetic covariates.
25OHD3 was also positively associated with creatinine, phosphate and calcium in all analyses, Tables 4 , 5 , and 6 ; although the association was borderline significant concerning phosphate in the adjusted dichotomised analysis, Table 6 .
Despite that, with a one‐sided test, the difference of 2.3 ml/min was borderline significant, and thus, if a difference is confirmed in an adequately powered study, it would be of major relevance since it would support ocular hypoperfusion in the NTG pathophysiology.
First, a borderline significant difference in mean age was found between the groups.
The finding, however, was borderline significant (95% CI 0.48–1.01).
A high malaria episode (IRR = 2.82; 95 % CI 1.0–7.9) was also observed among children under 5 years of age, though due to a greater variance this was only borderline significant.
The difference was statistically significant for the anterior location but was borderline significant for the lateral location.
As for the cancer to CVD transition, we found a borderline significant association for the lowest RII tertile, when considering the whole sample.
An inverse borderline significant association was found between leisure time physical activity and stroke among all participants in the multivariable adjusted model (HR: 0.86; 95% CI: 0.73–1.00; p for trend = 0.06) (Table 5 ).
The increase in birth weight was borderline significant with the risk of asthma [OR 0.81, 95% CI (0.67–1.01)] when birth weight was < 3.6, and no association was found when birth weight was ≥3.6 kg ( Figure 3 ).
The borderline significant difference in performance between Panzee and the humans favored Panzee when compared to the two younger groups of children (3 to 4 and 5 to 6-year-olds).
For example, the results of the subgroup analyses on the occupational environment and transmitters were borderline significant, while with a larger sample size, these results may have exhibited a greater statistical power.
However, replicon type exhibited a borderline significant association with fimH lineage: fimH1 isolates more frequently contained replicons other than FIB and FII (13/27 [48%]) than did fimH6 (8/41 [20%]) or fimH47 (5/15 [33%]) isolates ( P = 0.051).
Since the interactions between education and age group were only significant for balance, borderline significant for walking speed and non-significant for grip strength and chair stands, no ultimate conclusions can however be drawn on the age differences.
A prior meta-analysis of three RCTs (Hokusai VTE Cancer, SELECT-D, and ADAM VTE) assessed the efficacy and safety of DOACs in patients with CAT, and revealed borderline significant results for DOACs vs. dalteparin in terms of recurrent VTE (RR: 0.51, 95% CI: 0.25–1.03) and major bleeding (RR: 1.64, 95% CI: 1.00–2.69) ( 16 ).
After a multilevel pooled analysis, in which we added the inclusion site as a level in the model, tPA and IL-7-which were borderline significant before-became significant.