For ultra-rare missense variants, a large cluster of MPO gene-sets was significant (FDR = 0.056) and two GO/pathways clusters were borderline significant (FDR < 25%).
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Interestingly, TMSB15A also showed a significant prognostic value in a second cohort (GSE 2034) with similar characteristics, and for CFL1, we observed a strong trend with a borderline significant value in this cohort.
In the univariate analysis, the risk of PFD for the entire cohort was significantly affected by age >46 years (P=0.02), female gender (P=0.03), pathological stages II (P=0.04) and IIIA (P<0.001), tumor size >2.0 cm (P=0.009), number of positive lymph nodes ≥1 (P<0.01), NG1 (P=0.03), and NG2 (P=0.04), whereas the Ki-67 PI was borderline significant ( Table 5 ).
However, in planned subgroup analyses we observed a borderline significant increased dementia risk in recurrent users of ACB3 anticholinergics, defined as those participants who reported anticholinergic use at both baseline and two-year follow-up, more likely to reflect a longer term or continuous anticholinergic load.
Concerning mental health disadvantage, we found no association to risk of eLGA when the mother had poor mental health (aRR 0.98, 95% CI 0.83; 1.12) but a borderline significant association for the father having poor mental health (aRR 0.82, 95% CI 0.64; 1.00).
The results of this analysis were borderline significant, possibly because the analysis was underpowered despite the fact that we used a quite long recruitment period.
This confirms the reduction in glial density in BD in sgACC, and also shows a borderline significant decrease in glial number, but no difference in sgACC volume (Fig. 1 ).
When data from these two studies of ICPP were pooled (heterogeneity test: Q = 0.08, df = 1, P = 0.77, I 2 = 0%), the overall analysis showed that the difference between FAHSDS and initial HSDS in the experimental cohorts was 0.4 SDS higher than in the control cohorts (95% CI = −0.01–0.81, Z = 1.94, P = 0.05), a borderline significant result ( Figure 4(c) ). 4.
An increase in number of SNPs in the window resulted in a decrease in the LRT especially for the HHM approach, leading to the mean LRT being borderline significant at the genome wide 5% level for the largest window (with 72 SNPs)(see Supplementary Tables S3 and S5 ).
For all statistical analyses, p -values < 0.05 were considered statistically significant; p-values between 0.05 and 0.1 were considered borderline significant.
Preoperative chronic anemia was associated with postoperative complications at a borderline significant level (Table 7 ).
The independent samples t -test showed that the gender difference in the positive emotion scores was borderline significant, with males (M = 33.00, SD = 7.05) having higher positive emotion scores than females (M = 31.90, SD = 6.36), while the gender differences in the scores of the remaining variables (including “lying flat” tendency, satisfaction of BPN, happiness index, and negative emotion) were not significant. 3.2.2.
In general, minimally/borderline significant results in relation to breed susceptibility should be viewed with caution.
Our results revealed that incidence and mortality of bladder cancer showed significant or borderline significant difference according to regional distribution.
Association between the research variables, intention to seek MHO help, and actually consulting an MHO The variables regarding differences between soldiers who actually consulted an MHO and those who did not (Table 4 ) that were found significant or borderline significant were inserted into GLMs together with the outcome variables of intention to seek help and actually seeking MHO help.
Besides, patients with HBV showed significantly worse performance in the language function than those in the SVR group (with a borderline significant difference compared with the HCV group).
[ 15 ] found a borderline significant protective effect for children aged 12–23 months compared to children aged less than 12 months, and Tran et al.
While we did not find this association when assessing language spoken at home, this association was borderline significant (potentially due to the small subgroup size with < 10% of our sample speaking languages other than English).
The important predictors in the linear model ( \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$p < 0.05$$\end{document} p < 0.05 ) are mother, father and mgm for all imputation methods, except PCA where the mgm is borderline significant.
Although its role as a moderator in the regression model was only borderline significant, it appeared as a potential moderating variable between maternal stress and child emotional and behavioral characteristics.
We observed significant association between self-reported thyroid disorders and ASVs in Model 1 (β = −8.6, 95% CI: −15.9, −1.3) and Model 2 (β = −9.2, 95% CI: −17.2, −1.2); however, when additionally adjusted for urinary iodine status and periodontitis, the association became borderline significant in Model 3 (β = −8.2, 95% CI: −17.2, 0.8).
Reduction in individual care activities was significantly different between groups for TCs and was borderline significant for general practitioner visits ( Table 2 ).
A borderline significant interaction was also observed for DM versus non-DM ( p for interaction = 0.06), with a higher risk of death seen in patients with DM (OR 2.61, 95% CI 0.98–6.98, p = 0.05).
In the single dose TNF study, the level of expression of Mip-2 was increased in the Tnf+/+ mice 1 day after exposure and borderline significant 2 days after exposure.
In combination with the low number of included studies for those factors, this might explain why we only found a borderline significant association for varus thrust with knee OA.