Participants with mobile phone-related awakenings at BL and FUP had a significant increased risk to develop headache (OR M1 : 2.72 (CI: 1.01–7.36)) and a borderline significant risk to develop concentration problems (OR M1 : 2.67 (CI: 0.98–7.22)).
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In the literature
In the earliest study of intracoronary injection of AdFGF-4 (AGENT-2), delivery of active vector by subselective coronary catheterization of culprit arteries resulted in a borderline significant reduction in the size of the region of myocardium demonstrating stress hypoperfusion eight weeks post-delivery [ 145 ].
Demographics and patient characteristics were similar across the patient groups (ε2 carrier, ε3/ε3 and ε4 carrier), though presence of RF was borderline significant ( Table 2 ).
The median OS was associated with a borderline significant improvement in the oxaliplatin group (29.9 months, 95% CI 25.68–34.13) than in the irinotecan group (23.0 months, 95% CI 17.83–28.17; HR = 0.75, 95% CI 0.57–0.99; p = 0.043) ( Figure 2A ).
Recurrence is significant before adjustment for GA in the MVM broad category and borderline significant even after adjustment.
In univariate analysis, the risk of the composite endpoint was significantly higher in Qt-1 ( p = 0.030) and in Qt-5 ( p = 0.043) as compared to the Qt-3 reference, whereas both Qt-2 ( p = 0.055) and Qt-4 ( p = 0.071) demonstrated a borderline significant increase.
The criteria for statistical significance were set as follows: a p -value < 0.05 indicated a statistically significant difference, and a p -value between 0.05 and 0.1 was regarded as a borderline significant difference.
However, stratified analyses showed that paternal HCC was associated with a borderline significant lower total energy intake and significantly lower protein intake, but only among daughters (adjusted β: -42 kcal/day [95% CI: -85, 0] and -2.6 g/day [95% CI: -4.4, -0.8] per 100 pg/mg HCC, respectively).
This variable remained a borderline significant predictor for the development of high BP (hazard ratio = 1.21, 95% CI 1.00–1.46).
However, when adjusting for all factors in the multivariable analysis, only age (OR 1.05 per year, 95% CI 1.02–1.08) and physical inactivity (OR 2.48, 95% CI 1.40–4.38) remained significantly associated with an increased odds of death and ADL dependency at 3 months, while low education (OR 1.74, 95% CI 1.00–3.00) remained borderline significant ( Table 2 ).
Compared to EORTC reference values for colorectal (CRC) cancer patients, our cohort had borderline significant lower cognitive functioning and reported higher financial problems.
Even in healthy individuals of SHIP (replication sample II), extreme groups were still borderline significant regarding BDI and the highly inter-correlated ( r =0.77) TICS 21 ( Figure 4h ).
The findings of this study included (i) higher resting nitrite levels in diabetics than controls; (ii) a borderline significant decrease among control subjects in resting nitrite following the unfiltered car ride as compared to resting nitrites after the filtered ride; (iii) increased nitrites in controls but not diabetics during reactive hyperemia prior to exposure and abolition of this increase following acute TRAP exposure.
We found that differences existed in total work hours between urban and rural physicians who were employed by hospitals with basic emergency care responsibility in clinical specialty clusters 1 (borderline significant), 2, and 4.
In the physical domain, however, the lower motivation in the HD group relative to controls was weaker and only borderline significant when controlling for the capacity of participants to perform the task.
For total iron there was a borderline significant interaction detected ( P 0.05, Table 4 ); among former smokers, an inverse association with lung cancer risk was detected (HR per 1 SD 0.90, 95% CI 0.83 – 0.97).
Another meta-analysis, on which the NIH Consensus Statement was based, found a borderline significant effect from 14 RCTs for the combined outcome of death or BPD (RR 0.93, 95% CI 0.86–0.99, n = 3129) [ 129 , 130 ].
Moreover, each 10°proclination of the lower incisors resulted in a borderline significant average change in point B of 0.3 mm in the horizontal plane.
We also observed this effect in our broader review, although it was smaller and borderline significant, which may be due to greater heterogeneity in the included populations [ 55 ].
In addition, the borderline significant association of SLCO1B3 polymorphisms with anemia indicates a nuanced role in MTX-related hematological toxicity, thus requiring further investigation.
Even though the bootstrap analysis gave similar results, and in three cases borderline significant findings even became significant, we decided to keep a more conservative approach to prevent overstating the results.
In the current post hoc analysis of the GOLD study, patients randomized to CGM were approximately gaining a half kilogram in weight (borderline significant).
Due to the small numbers of patients with breast cancer in our cohort, this finding was only borderline significant in multivariable analysis (Table 3 ).
All prognostic variables found to be significant or borderline significant in univariate analysis were included in multivariate analysis using the Cox proportional hazards regression model.
Adjustment for CVD risk factors, including systolic blood pressure, HDL-cholesterol, BMI and diabetes status caused the association between C20:0 and all-cause mortality to become insignificant, while the association between C24:0 and all-cause mortality became borderline significant.