“borderline significant”

The positive trend observed for the physical quality-of-life with slightly increasing median score from 52.6 at T0, 52.7 at T1, 54.0 at T6, and 55.6 at T12 and the borderline significant differences between T0 and T12 need to be further investigated in a larger sample size.

Discussion The main findings of this study were that TNFR2 was associated with higher mortality, but that TNFR1 showed borderline significant associations, and that neither TNFR1 nor TNFR2 was associated with eGFR decline in patients with CKD when adjusting also for baseline eGFR and urine-protein.

However, the small number of patients on long-term sick leave, a rather large (borderline significant) baseline difference, and the fact that the secondary outcome measuring level of sick leave did not show the same effect, warrant caution when interpreting these results.

Further exploration revealed that this position refinement was not specific to the map used in the analysis, as simulated QTL experiments as well as adding the additional QTL (that are borderline significant or only ‘suggestive’) to the HC1 and HC2 models yield similar effects (not shown).

One analysis reported a “borderline significant” 7% increase in overall cancer risk; however, the confidence interval (CI) included 1 [ 34 •].

Further, a transcriptome-wide association study (TWAS) from our group identified KLHL17 as a borderline significant gene in the pancreas and multi-tissue models (Z = −3.96, FDR = 0.052; FDR = 0.063, respectively) 28 .

As shown in Supplementary Table S10 only mutations in groups of miRNA genes coding for miR-509-3p show borderline significant association with a decrease of the miRNA level.

Incidence at ages 1–4 years was higher in wards classed as rural than in those classed as urban or mixed; the test for heterogeneity was borderline significant.

These subgroup findings reached a borderline significant interaction, implying that the severity of kidney disease could modulate the renal response to BP control.

In the adjusted model, a borderline significant association was found between religion and hypertension development among PLWH.

A significant increase in proteinuria following the stenting was found at 1 and at 12 months, while the increment in proteinuria observed at the other control times was only borderline significant.

This yielded a borderline significant increased risk of late AMD for persons homozygous for rs3793784 (OR 1.39, 95%CI 1.02–1.89).

The differences between the two estimates were relatively small for most of the indicators and the difference was borderline significant for only one indicator.

However, when we performed age-matched HLA association testing with 49 PBC with HCC patients and 49 PBC without HCC patients ( Supplementary Table 7 ), HLA-DRB1*09:01:02 , HLA-DQB1*03:03:02 , HLA-DRB1*09:01:02-HLA-DQB1*03:03:02 remained borderline significant after adjusting for multiple comparisons.

However, the univariate and multivariate meta-regression analyses did not detect a borderline significant association between PFS and pretrial EGFR test, or other characteristics 33 , 34 (Table 3 ).

In addition, the IMS score for interest and enjoyment and the total IMS score showed borderline significant differences between the groups.

Pooling of prospective cohorts with nested case-control studies of saturated fats resulted in a borderline significant association with CHD mortality but not total CHD or type 2 diabetes (appendix 4 eFigures 51-53).

The effects of MitoG228A on cataracts also appears independent from metabolic dysfunction; MitoG228A had no significant effect on metabolic markers, although hemoglobin A1C, HDL, and triglycerides were borderline significant.

We find borderline significant effects of BCG coverage as shown in Fig. 3 : higher BCG coverage seems to help slow down the growth in both COVID-19 related deaths.

Only the T87 KO2 10% decrease in post-treatment viability was borderline significant when compared to the NTC1 control, with a p -value of 0.06.

Overall, there was a borderline significant association between animal contact and odds of HEV IgG seropositivity (OR = 1.25, 95% CI [0.97, 1.62]).

Given the borderline significant (albeit high magnitude of point estimate) findings showing increasing UAS responsiveness of females versus males, we cannot exclude the possibility of post-menopausal status with increased age as a potential explanatory factor.

In clear emotional prosody, there was a significant correlation with the mIRI cognitive empathy subscale and a borderline significant correlation with the full mIRI (Fig. 2 ).

A P value <0.05 was considered as statistically significant, and P value <0.05 was considered as borderline significant for all the statistical procedures.

We found a borderline significant increase of OAMZL risk associated with exposure to one or more domestic animals, especially to dogs.